A:Cancer viruses/SV-40

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Cancer Viruses

SV-40, a pro-cancer virus in vaccines

In 1955, Jonas Salk performed a medical miracle when he discovered how to

mass produce polio vaccine by growing it on the kidneys of rhesus monkeys.

While there is no question that thousands were saved from the ravages of

polio by the Salk vaccine, by 1960 a problem had surfaced -- researchers had

isolated a viral contaminate in the vaccine, Simian (monkey) Virus # 40. It

seems that when the live polio virus grown on monkey tissues was extracted

for vaccine production this SV-40 virus was extracted as well.

When SV-40 was injected into research animals it produced brain cancer. It

appears our government didn't wish to create a public panic or discredit the

public health service, because instead of recalling the tainted vaccines, it

quietly ordered the manufacturers to find a monkey free of SV-40 and continue

production. As of 1963, the rhesus monkey had been replaced with the African

green monkey for production of a safer polio vaccine, but between the years

of 1955 and 1963 as many as 98 million Americans had received doses of live

polio virus vaccines tainted with SV-40.

Nowadays SV-40 has appeared in 61% of all new cancer patients -- patients too

young to have received the contaminated vaccine being administered forty

years ago who are now believed to have been infected by human to human

transmission. Being a blood born organism, it is also suspected that SV-40 is

transmissible from mother to child during pregnancy. The more this matter is

researched the more startling the evidence. Senior epidemiologist at the

National Institutes of Health, Dr. Strickler, has plotted a geographic

pattern to the cancers associated with SV-40 helping to confirm its link to

the tainted vaccine. People who lived in Massachusetts and Illinois who

received identified lot numbers of the contaminated vaccine administered in

the 1950s are now demonstrating ten times the rate of the osteosarcoma bone

tumors as those who received vaccine free of the SV-40 contaminate in other

parts of the country.

DNA Polyoma Viruses

In 1964, studies were conducted on a polyoma virus (a tumor-producing DNA

virus). It was discovered that the persistent genetic DNA material in the

polyoma virus brought about malignant transformations in hamster embryo cell

cultures. This was reported in the November 23, 1964 issue of the Journal of

the American Medical Association.

SV-40 is one example of a DNA polyoma virus. Polyoma (many tumor-causing)

viruses cause prolonged infection where tissue is destroyed, integrate into

the hosts genetic material, are capable of mutating a cell, may reproduce

after coming into contact with a 'helper' virus, enable the separate

replication of the viral genome, can generate immune responses, and they can

induce malignancy. Scientists are amazed at how little genetic information

these viruses carry in proportion to the damage they can cause.

The 'D' in DNA and the 'R' in RNA have characteristics which are dependent on

the kind of sugar molecule associated with it. DNA exists predominantly in

the nucleus, but is also represented in the cytoplasm and in the

mitochondria. RNA is also present in the cytoplasm. When viral RNA or DNA

combines with the genetic material in the cell itself, the viral genetic

material can become part of the host cell genetic code, altering the genetic

structure of the cell. When the altered cell duplicates, the encoded viral

genetic material may affect cellular processes in such a way as to produce

abnormal cells, which sometimes become malignant or cancerous.

Cancer-Causing RNA Viruses and DNA proviruses

The discovery in 1975 that viruses causing cancer in animals had a special

enzyme called reverse transcriptase makes the problem even more interesting.

These kind of viruses are called RNA viruses. When an RNA virus has the

reverse transcriptase enzyme within its structure, it allows the virus to

actually form strands of DNA which easily integrate with the DNA of the host

cell which it infects. Studies by Dr. Simpson of Rutgers University

indicate that RNA viruses which do not cause cancer can also form DNA, even

without the presence of reverse transcriptase. DNA formed in this way from an

RNA virus is called a provirus. It is known that some non-cancerous viruses

have a tendency to exist as proviruses for long periods of time in cells

without causing any apparent disease. In other words, they remain latent.

Some examples of common RNA viruses that do not cause cancer, per se, but

have the capacity to form proviruses are influenza, measles, mumps and polio

viruses.

Viruses as Catalysts for Cancer

An article in the January 6, 1962 Science Newsletter indicated that 'common

human viruses act as carriers in causing cancer by interacting with

cancer-causing chemicals; this has been indicated by experiments which show

that cancer-causing substances that are present in too small a quantity by

itself will become active and create tumors when combined with single doses

of virus. Malignant tumors appeared in five type of injected mice.' The

viruses mentioned were ECHO9, B-4, sackie, and Polio virus 2. The article

further indicated that 'viruses may also activate other cancer causing

substances besides chemicals in the environment, such as DMBA, AF, and DBA.'

Even common non-tumor viruses, including those in smallpox vaccine and polio

virus 2, can act as carcinogens. It was reported in Science on December 15,

1961 that these common viruses acted as catalysts in producing cancer when

given to mice in combination with known organic carcinogens in amounts too

small to induce tumors themselves. This means that some vaccinations will

induce cancer, when combined with the growing problem of environmental

pollution from toxic by-products of agriculture (pesticides on and in food)

and industry.

A Listing of Cancer Causing Microbes

The July 14th 1997 issue of Business Week has an article in it about how many

cancers are being linked to various viruses, and bacteria ,and parasites.

Among the organisms now linked to cancer are as follows

Microbe Type of Cancer

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Hepatitis B Virus Liver Cancer

Human Papiloma Virus ( HPV ) Cervical Cancer

Heliobacter Pylori Stomach Cancer

HTLV-1 A type of Leukemia in Japan

Epstein- Barr virus (EBV) Burketts Lymphoma, naso pharyngeal

cancer

Kaposi's Sarcoma Herpes Virus (KSHV) Kaposi's Sarcoma, and 100 % of

Myeloma cases.

Schistosomiasis Bladder Cancer

Liver Flukes Liver and biliary cancer

Helicobacter hepaticus Liver cancer

Hepatitis C Virus Liver cancer

Papillomaviruses (HPV-5,HPV-8,HPV-17) Skin cancer

Polyomavirus (BK and JC) Neural tumors? and insulinomas?

Retrovirus (HTLV-2) Hairy-cell leukemia

Lyme Disease bacteria B. Burgdorferi Skin and Breast cancer

Epstein-Barr Virus Majority of Non-Hogkins lymphoma (sp)

Granuloma type Virus Skin Cancer (Not confirmed)

References

Fisher, B. L. (1997). Workshop on Simian Virus 40: A Possible Human

Polyomavirus. National Vaccine Information Center, January 27, On-line at

http://www.909shot.com/polio197.html

Carbone, M., et al. (1996). SV-40 Like Sequences in Human Bone Tumors.

Oncogene, 13(3), 527-535.

Elswood, B. F., & Stricker, R. B. (1995). Polio Vaccines and the Origin of

AIDS. Medical Hypotheses, 42(6), 347-354.

Krieg, P., Amtmann E, Jonas, D., Fischer, H., Zang, K., & Sauer G. (1981).

Episomal Simian Virus 40 Genomes in Human Brain Tumors. Proceedings of the

National Academy of Sciences of the United States of America, 78(10),

6446-6450.

Lednicky, J. A., Garcea, R. L., Bergsagel, D. J., & Butel, J. S. (1995).

Natural Simian Virus 40 Strains are Present in Human choroid Plexus and

Ependymoma tumors. Virology, 212(2), 710-717.

i, F., et al. (1995). Human Brain Tumors and Simian Virus 40. Journal

of the National Cancer Institute, 87(17), 1331.

i, F., et al. (1996). SV-40 Early Region and Large T Antigen in Human

Brain Tumors, Peripheral Blood Cells, and Sperm Fluids From Healthy

Individuals. Cancer Research, 56(20), 4820-4825.

Pass, H. I., Kennedy, R. C., & Carbone, M. (1996). Evidence for and

Implications of SV-40 Like Sequences in Human Mesotheliomas. Important

Advances in Oncology, 89-108.

Rock, A. (1996). The Lethal Dangers of the Billion Dollar Vaccine Business.

Money, December, pages 148-163.

Tognon, M., et al. (1996). Large T Antigen Coding Sequences of Two DNA Tumor

Viruses, BK and SV-40, and Nonrandom Chromosome Changes in Two Glioblastoma

Cell Lines. Cancer Genetics and Cytogenics, 90(1), 17-23.

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