Guest guest Posted September 5, 1998 Report Share Posted September 5, 1998 Thanks . That was very interesting info. But what is he referring to when he mentions " alcohol fractionation process " and " solvent-detergent method " ? Are these treatments for tetanus? Kate At 07:33 PM 9/5/98 PDT, you wrote: >From: " G " <mom2q@...> > > >I found this in some old archives I have from e-mails. I found it >interesting. It was written by a doctor keep in mind. > > > > >><<Subject: Re: Tetanus immune globulin >> >><<< What I'm asking is if you could compare what you know about both >and some >>of the reasoning behind your personal decision that the vaccine is much >>safer.>>> >> >><<<But what types of things do you think the alcohol fractionation >process >>misses in the plasma donated by what you consider less-than-desirable >donors? >>>>> >> >>The risk of serious reactions to tetanus vaccine is exceedingly rare >(although >>I have personally witnessed/treated an anaphylactic response to tetanus >toxoid >>-- see my previous post on this). The risk of adverse reaction >increases with >>each additional vaccination/booster given. It is quite common to have >local >>discomfort, and perhaps even swelling and some redness, after a >vaccination. >>It is possible, but much less common, to have >>general " creepy " symptoms for a day or two, even up to a week in rare >cases. >>But serious reactions with or without long-term sequelae are far lower >for >>tetanus toxoid than for any other vaccine. The effectiveness of the >vaccine >>is also the highest of all commercially-available vaccines. >> >>The organism that causes tetanus (Clostridium tetani) is widely >distributed in >>soil almost everywhere, especially in climates with abundant rain. >Although >>the common myth is that " stepping on a rusty nail " is the source of >infection, >>actually any puncture wound, however minor, can carry the offending >organism >>into the body. The organism can only grow in the absence of oxygen, so >some >>type of puncture wound or other relatively deep, narrow >>wound is typical. Many ordinary wounds fall into this category, >however, the >>most common being in people who encounter an unexpected thorn while >>gardening..... although the wound itself may seem quite trivial, the >>possibility of C. tetani infection is very real. >> >>Most physicians have never seen a case of tetanus, and are unlikely to >even >>include it in an initial differential diagnosis when evaluating a >patient with >>appropriate symptoms. The offending wound may have been so minor that >the >>patient will not recall it, even in the most detailed of medical >histories. >>So it is not reasonable to assume that the need for TIG in an >unvaccinated >>person will be recognized at an appropriate time, because the illness >>may not be diagnosed at all. The question of availability of >non-expired TIG >>is another valid issue. >> >>The alcohol-fractionation method is highly effective against HIV (which >is >>actually a fairly fragile virus), but the research that I have read has >left >>me with many doubts regarding its effectiveness against Hepatitis B and >>Hepatitis C. Hep B, especially, is an incredibly durable virus.... it >can >>survive and remain infectious at room temperatue on a hard surface for >at >>least a week, even after the surface being washed down with >>alcohol!! (This is why my children are all immunized against Hep >It can >>also survive extremes in temperature. >> >>The solvent-detergent method is better, but still not 100%. >Solvent-detergent >>plus heat-treating, followed by alcohol-fractionation appears to be >very, very >>safe, but this sequence of treatments is quite expensive, and not FDA >>required. Alpha Therapeutic Corporation does both solvent-detergent >and heat- >>treatment procedures -- I don't know for sure about other >manufacturers. But >>God forbid you should be in need of TIG and be at a small community >>hospital and their TIG is from a company that you don't know anything >about! >> >>Food for thought..... >> >>Dr. Mari >> >> >> >> >> >> >> >> >> >> >> >> >> >> > > >------------------------------------------------------------------------ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 5, 1998 Report Share Posted September 5, 1998 Good point Lana. I really think this doctor is going WAY overboard when he said this. All the research I have read has never mentioned this. Its main routes of spread are through sexual contact, through contaminated blood transfusions and through sharing equipment used for injecting illegal drugs. However it is " POSSIBLE " to get it through other body fluids though no where in the search I did stated that it can live at least a week on a hard surface. I think he is full of it personally!! Since this was an old e-mail I had archived I don't know exactly where it came from but I think we are right on this one. Re: Tetanus immune globulin >>> >>><<< What I'm asking is if you could compare what you know about both >>and some >>>of the reasoning behind your personal decision that the vaccine is much >>>safer.>>> >>> >>><<<But what types of things do you think the alcohol fractionation >>process >>>misses in the plasma donated by what you consider less-than-desirable >>donors? >>>>>> >>> >>>The risk of serious reactions to tetanus vaccine is exceedingly rare >>(although >>>I have personally witnessed/treated an anaphylactic response to tetanus >>toxoid >>>-- see my previous post on this). The risk of adverse reaction >>increases with >>>each additional vaccination/booster given. It is quite common to have >>local >>>discomfort, and perhaps even swelling and some redness, after a >>vaccination. >>>It is possible, but much less common, to have >>>general " creepy " symptoms for a day or two, even up to a week in rare >>cases. >>>But serious reactions with or without long-term sequelae are far lower >>for >>>tetanus toxoid than for any other vaccine. The effectiveness of the >>vaccine >>>is also the highest of all commercially-available vaccines. >>> >>>The organism that causes tetanus (Clostridium tetani) is widely >>distributed in >>>soil almost everywhere, especially in climates with abundant rain. >>Although >>>the common myth is that " stepping on a rusty nail " is the source of >>infection, >>>actually any puncture wound, however minor, can carry the offending >>organism >>>into the body. The organism can only grow in the absence of oxygen, so >>some >>>type of puncture wound or other relatively deep, narrow >>>wound is typical. Many ordinary wounds fall into this category, >>however, the >>>most common being in people who encounter an unexpected thorn while >>>gardening..... although the wound itself may seem quite trivial, the >>>possibility of C. tetani infection is very real. >>> >>>Most physicians have never seen a case of tetanus, and are unlikely to >>even >>>include it in an initial differential diagnosis when evaluating a >>patient with >>>appropriate symptoms. The offending wound may have been so minor that >>the >>>patient will not recall it, even in the most detailed of medical >>histories. >>>So it is not reasonable to assume that the need for TIG in an >>unvaccinated >>>person will be recognized at an appropriate time, because the illness >>>may not be diagnosed at all. The question of availability of >>non-expired TIG >>>is another valid issue. >>> >>>The alcohol-fractionation method is highly effective against HIV (which >>is >>>actually a fairly fragile virus), but the research that I have read has >>left >>>me with many doubts regarding its effectiveness against Hepatitis B and >>>Hepatitis C. Hep B, especially, is an incredibly durable virus.... it >>can >>>survive and remain infectious at room temperatue on a hard surface for >>at >>>least a week, even after the surface being washed down with >>>alcohol!! (This is why my children are all immunized against Hep >>It can >>>also survive extremes in temperature. >>> >>>The solvent-detergent method is better, but still not 100%. >>Solvent-detergent >>>plus heat-treating, followed by alcohol-fractionation appears to be >>very, very >>>safe, but this sequence of treatments is quite expensive, and not FDA >>>required. Alpha Therapeutic Corporation does both solvent-detergent >>and heat- >>>treatment procedures -- I don't know for sure about other >>manufacturers. But >>>God forbid you should be in need of TIG and be at a small community >>>hospital and their TIG is from a company that you don't know anything >>about! >>> >>>Food for thought..... >>> >>>Dr. Mari >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >> >> >>------------------------------------------------------------------------ >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 6, 1998 Report Share Posted September 6, 1998 >>The is highly effective against HIV (which >is >>actually a fairly fragile virus), but the research that I have read has >left >>me with many doubts regarding its effectiveness against Hepatitis B and >>Hepatitis C. Hep B, especially, is an incredibly durable virus.... it >can >>survive and remain infectious at room temperatue on a hard surface for >at >>least a week, even after the surface being washed down with >>alcohol!! (This is why my children are all immunized against Hep I think that it was referring to the alcohol-fractionation method (other words cleaning) to kill Hepatitus which further confuses me!!! It was my understanding that only sexually active, needlesharers, or health care workers were at risk for Hep B... Am I missing something??..or did this just say that Hep B can live at room temp on hard surfaces--which would mean that it was an airborne virus... confused, Lana At 10:45 PM 9/5/98 -0400, you wrote: >From: mkpeters@... > >Thanks . That was very interesting info. But what is he referring >to when he mentions " alcohol fractionation process " and " solvent-detergent >method " ? Are these treatments for tetanus? > >Kate > > >At 07:33 PM 9/5/98 PDT, you wrote: >>From: " G " <mom2q@...> >> >> >>I found this in some old archives I have from e-mails. I found it >>interesting. It was written by a doctor keep in mind. >> >> >> >> >>><<Subject: Re: Tetanus immune globulin >>> >>><<< What I'm asking is if you could compare what you know about both >>and some >>>of the reasoning behind your personal decision that the vaccine is much >>>safer.>>> >>> >>><<<But what types of things do you think the alcohol fractionation >>process >>>misses in the plasma donated by what you consider less-than-desirable >>donors? >>>>>> >>> >>>The risk of serious reactions to tetanus vaccine is exceedingly rare >>(although >>>I have personally witnessed/treated an anaphylactic response to tetanus >>toxoid >>>-- see my previous post on this). The risk of adverse reaction >>increases with >>>each additional vaccination/booster given. It is quite common to have >>local >>>discomfort, and perhaps even swelling and some redness, after a >>vaccination. >>>It is possible, but much less common, to have >>>general " creepy " symptoms for a day or two, even up to a week in rare >>cases. >>>But serious reactions with or without long-term sequelae are far lower >>for >>>tetanus toxoid than for any other vaccine. The effectiveness of the >>vaccine >>>is also the highest of all commercially-available vaccines. >>> >>>The organism that causes tetanus (Clostridium tetani) is widely >>distributed in >>>soil almost everywhere, especially in climates with abundant rain. >>Although >>>the common myth is that " stepping on a rusty nail " is the source of >>infection, >>>actually any puncture wound, however minor, can carry the offending >>organism >>>into the body. The organism can only grow in the absence of oxygen, so >>some >>>type of puncture wound or other relatively deep, narrow >>>wound is typical. Many ordinary wounds fall into this category, >>however, the >>>most common being in people who encounter an unexpected thorn while >>>gardening..... although the wound itself may seem quite trivial, the >>>possibility of C. tetani infection is very real. >>> >>>Most physicians have never seen a case of tetanus, and are unlikely to >>even >>>include it in an initial differential diagnosis when evaluating a >>patient with >>>appropriate symptoms. The offending wound may have been so minor that >>the >>>patient will not recall it, even in the most detailed of medical >>histories. >>>So it is not reasonable to assume that the need for TIG in an >>unvaccinated >>>person will be recognized at an appropriate time, because the illness >>>may not be diagnosed at all. The question of availability of >>non-expired TIG >>>is another valid issue. >>> >>>The alcohol-fractionation method is highly effective against HIV (which >>is >>>actually a fairly fragile virus), but the research that I have read has >>left >>>me with many doubts regarding its effectiveness against Hepatitis B and >>>Hepatitis C. Hep B, especially, is an incredibly durable virus.... it >>can >>>survive and remain infectious at room temperatue on a hard surface for >>at >>>least a week, even after the surface being washed down with >>>alcohol!! (This is why my children are all immunized against Hep >>It can >>>also survive extremes in temperature. >>> >>>The solvent-detergent method is better, but still not 100%. >>Solvent-detergent >>>plus heat-treating, followed by alcohol-fractionation appears to be >>very, very >>>safe, but this sequence of treatments is quite expensive, and not FDA >>>required. Alpha Therapeutic Corporation does both solvent-detergent >>and heat- >>>treatment procedures -- I don't know for sure about other >>manufacturers. But >>>God forbid you should be in need of TIG and be at a small community >>>hospital and their TIG is from a company that you don't know anything >>about! >>> >>>Food for thought..... >>> >>>Dr. Mari >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >>> >> >> >>------------------------------------------------------------------------ >> Quote Link to comment Share on other sites More sharing options...
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