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Bromelain

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Ken, my Naturopath prescribed Bromelain for digestive problems. He calls it

an " ulcer medication " .

I am starting at 500 mg. daily, though he prescribed taking 2 500 mg. 3x

daily. He never remembers how sensitive I am to meds and supplements.

Even at 500 mg. I feel as though my heart is beating more quickly, then a

couple of hours later, I tend to fall into a dead sleep.

Any comments? I am not taking any antibiotics right now.

Kathy

Re: Bromelain

> Definitely bromelain potentates antibiotics -- I stopped herxing

> after 3 weeks with just antibiotics, but when bromelain was added ..

> the herx continued for months...

>

> see http://www.folkarts.com/idef/recovery1.htm for details.

>

> Wife had the same experience.

>

>

> This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

>

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My eldest daughter cannot take bromelain because she is very

sensistive to salcycilates (thus she cannot take aspirin, grape seed

extract, olive leaf extract etc...) - this salcycilate sensistivity

does happen with CFIDS for some people...

You did not mention taking antibiotics with it, so I am assuming that

is NOT the case... then that type of reaction is an area of concern..

one possibility is salcycilate sensistivity. Another is that people

who are sensistive to bee stings (allergic reaction) may react to

bromelain.

I would suggest stopping for the moment. See if other salcycilates

(for example, aspirin) cause a reaction. If they do... you are in the

same boat as my eldest daughter... which reduces your options for non-

prescription treatment.

AS ALWAYS - not medical advise.

> Ken,

> Even at 500 mg. I feel as though my heart is beating more quickly,

then a

> couple of hours later, I tend to fall into a dead sleep.

>

> Any comments? I am not taking any antibiotics right now.

>

> Kathy

>

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  • 8 months later...

cures for cancer <cures for cancer >

From: Harvey Maltz <harvmal@...>

Date sent: Thu, 04 Oct 2001 22:57:31 -0400

Send reply to: cures for cancer

Subject: Bromelain

>BromelainHere's everything you ever wanted to know about

>bromelain,moonbeam,and even things you didn't want to know.One of the most

>interesting things to me is its potentiation of many drugs and its potent

>anti-inflammatory effect. harvey Bromelain: A Literature Review and

>discussion of its Therapeutic Applications S. , N.D.

Hi Harvey,

What a great article on Bromelain. Maybe it was the home

made,

pineapple juice derived Bromelain, in Protocol 1 that caused my neighbour to

recover from

her stage 4 lung cancer in just 5 months. Or maybe it was the combination of

things in

Protocol 1.

Good one, Harvey.

moonbeam

Bromelain ......Antitumor...

The first documented use of oral bromelain on cancer patients was in 1972.

Twelve patients with ovarian and breast tumors were given 600 mg of

bromelain daily for from 6 months to several years, with reported

resolution of some of the cancerous masses and a decrease in metastasis.19

Bromelain in doses of over 1000 mg daily has been combined with

chemotherapeutic agents such as 5-FU and vincristine, and has been

reported to result in tumor regression.19,20

Bromelain has also decreased lung metastasis of lung cancer cells

implanted in mice in a dose-dependent manner. This antimetastatic

potential was demonstrated by both the active and inactive bromelain, with

or without proteolytic and anticoagulant properties.21,22

--------------------------------------------------------------------------

------

Cytokine Induction

The successful initiation of an immune response depends on T cells and

macrophages, along with the polypeptide factors they produce, called

cytokines, which play a key role in communication during normal

immunological response as well as infectious, inflammatory, and neoplastic

disease states. Table 3 lists cytokines and their activities.

Bromelain, papain, and amylase have all been demonstrated to induce

cytokine production in human peripheral blood mononuclear cells. Treatment

leads to the production of tumor necrosis factor-alpha (TNF-alpha),

interleukin-1-beta (IL-1 beta), and interleukin-6 (IL-6) in a time and

dose-dependent manner. Interferon-alpha (IFN-alpha) and interferon-gamma

(IFN-gamma), which had no effect alone, synergistically increased

TNF-alpha production when applied together with the enzymes.23,24 The

tryptic but not the autolytic fractions of papain and bromelain have a

higher (10- to 40-fold) inducing capacity for TNF production than the

untreated enzyme.25 Trypsin alone had only a small inducing effect.

The ability to induce cytokine production may explain the antitumor

effects observed after oral administration of polyenzyme preparations.

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  • 9 months later...
Guest guest

Interesting anecdote to relate to the list here -- about 4 months ago when I

started ramping up my cardio (hiking/climbing training) for climbing season,

I started to take dried pineapple chunks with me as a trail snack. I'd been

suffering from plantar fascitis since about March, and including a lot of

icing/foot massage in between 2- and 3-day climbs. When I learned (merely a

month ago) about the anti-inflammatory properties of bromelain, found in

pineapple, I had to marvel at the body's natural tendencies to crave what it

most needs... and to be effective in telling me precisely what that was!!

Wish those signals were as strong for everyone out there -- we might have a

much healthier population if people knew how to read their own body's

signals!

Anyone know whether juice, dried (sugary - yum!) or canned chunks would be

better sources, or are they all roughly the same? It doesn't appear as

though bromelain is something that will ever be listed on food labels...

Courtenay Schurman, CSCS

Seattle, WA

Body Results

www.bodyresults.com

court@...

Bromelain

Dr Siff,

I'm interested to know which brand of bromelain you take. In Australia,

bromelain is only available in tablet form in very insignificant potencies.

I would like to find high potency bromelain capsules that I can purchase

over the net. Do you have any suggestions?

[i shop around at the local " Health " stores for the best deals and these

sometimes

offer some good specials. For some reason bromelain tends to be quiet

expensive,

but, paradoxically one can find it in tablets mixed with papain at a

fraction of

the price for the bromelain product on its own . The usual does in these

combined

tablets is 450-500mg of bromelain and at least 250mg of papain. Vitamin

Cottage,

Walgreens and Rite Aid are a few of the stores where I buy these products.

Others may

have better sources. Incidentally, I take bromelain (at least 1500mg a day)

because

some research has reported on its value in managing certain cardiac disease

and

cholesterol levels. You may have other reasons for taking it. Sometimes I

just buy

plenty of (very cheap) natural pineapple juice because I am sure that a few

glasses a day

of that offers plenty of bromelain for most uses. Mel Siff]

Thanks,

Shanahan,

Melbourne

Australia.

Modify or cancel your subscription here:

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wish them to be published!

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Guest guest

Interesting anecdote to relate to the list here -- about 4 months ago when I

started ramping up my cardio (hiking/climbing training) for climbing season,

I started to take dried pineapple chunks with me as a trail snack. I'd been

suffering from plantar fascitis since about March, and including a lot of

icing/foot massage in between 2- and 3-day climbs. When I learned (merely a

month ago) about the anti-inflammatory properties of bromelain, found in

pineapple, I had to marvel at the body's natural tendencies to crave what it

most needs... and to be effective in telling me precisely what that was!!

Wish those signals were as strong for everyone out there -- we might have a

much healthier population if people knew how to read their own body's

signals!

Anyone know whether juice, dried (sugary - yum!) or canned chunks would be

better sources, or are they all roughly the same? It doesn't appear as

though bromelain is something that will ever be listed on food labels...

Courtenay Schurman, CSCS

Seattle, WA

Body Results

www.bodyresults.com

court@...

Bromelain

Dr Siff,

I'm interested to know which brand of bromelain you take. In Australia,

bromelain is only available in tablet form in very insignificant potencies.

I would like to find high potency bromelain capsules that I can purchase

over the net. Do you have any suggestions?

[i shop around at the local " Health " stores for the best deals and these

sometimes

offer some good specials. For some reason bromelain tends to be quiet

expensive,

but, paradoxically one can find it in tablets mixed with papain at a

fraction of

the price for the bromelain product on its own . The usual does in these

combined

tablets is 450-500mg of bromelain and at least 250mg of papain. Vitamin

Cottage,

Walgreens and Rite Aid are a few of the stores where I buy these products.

Others may

have better sources. Incidentally, I take bromelain (at least 1500mg a day)

because

some research has reported on its value in managing certain cardiac disease

and

cholesterol levels. You may have other reasons for taking it. Sometimes I

just buy

plenty of (very cheap) natural pineapple juice because I am sure that a few

glasses a day

of that offers plenty of bromelain for most uses. Mel Siff]

Thanks,

Shanahan,

Melbourne

Australia.

Modify or cancel your subscription here:

http://groups.yahoo.com/mygroups

Don't forget to sign all letters with full name and city of residence if you

wish them to be published!

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Guest guest

Interesting anecdote to relate to the list here -- about 4 months ago when I

started ramping up my cardio (hiking/climbing training) for climbing season,

I started to take dried pineapple chunks with me as a trail snack. I'd been

suffering from plantar fascitis since about March, and including a lot of

icing/foot massage in between 2- and 3-day climbs. When I learned (merely a

month ago) about the anti-inflammatory properties of bromelain, found in

pineapple, I had to marvel at the body's natural tendencies to crave what it

most needs... and to be effective in telling me precisely what that was!!

Wish those signals were as strong for everyone out there -- we might have a

much healthier population if people knew how to read their own body's

signals!

Anyone know whether juice, dried (sugary - yum!) or canned chunks would be

better sources, or are they all roughly the same? It doesn't appear as

though bromelain is something that will ever be listed on food labels...

Courtenay Schurman, CSCS

Seattle, WA

Body Results

www.bodyresults.com

court@...

Bromelain

Dr Siff,

I'm interested to know which brand of bromelain you take. In Australia,

bromelain is only available in tablet form in very insignificant potencies.

I would like to find high potency bromelain capsules that I can purchase

over the net. Do you have any suggestions?

[i shop around at the local " Health " stores for the best deals and these

sometimes

offer some good specials. For some reason bromelain tends to be quiet

expensive,

but, paradoxically one can find it in tablets mixed with papain at a

fraction of

the price for the bromelain product on its own . The usual does in these

combined

tablets is 450-500mg of bromelain and at least 250mg of papain. Vitamin

Cottage,

Walgreens and Rite Aid are a few of the stores where I buy these products.

Others may

have better sources. Incidentally, I take bromelain (at least 1500mg a day)

because

some research has reported on its value in managing certain cardiac disease

and

cholesterol levels. You may have other reasons for taking it. Sometimes I

just buy

plenty of (very cheap) natural pineapple juice because I am sure that a few

glasses a day

of that offers plenty of bromelain for most uses. Mel Siff]

Thanks,

Shanahan,

Melbourne

Australia.

Modify or cancel your subscription here:

http://groups.yahoo.com/mygroups

Don't forget to sign all letters with full name and city of residence if you

wish them to be published!

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Guest guest

, logic dictates that fresh pineapple would have the most bromelain

and any means of processing would reduce the potency. Try getting some

pineapples and slicing them and putting in a baggie for the trips. They

would provide the sugar(fructose), bromelain, and liquid (but would be

messy!).

Or you could get a small sealed container and make a fruit/nut salad-apples,

raisins, pineapples, almonds, walnuts, etc.--sort of like a healthy gorp.

Charlie Newkerk, C.S.C.S.

Rockledge, Fl

----- Original Message -----

> Interesting anecdote to relate to the list here -- about 4 months ago when I

> started ramping up my cardio (hiking/climbing training) for climbing season,

> I started to take dried pineapple chunks with me as a trail snack. I'd been

> suffering from plantar fascitis since about March, and including a lot of

> icing/foot massage in between 2- and 3-day climbs. When I learned (merely a

> month ago) about the anti-inflammatory properties of bromelain, found in

> pineapple, I had to marvel at the body's natural tendencies to crave what it

> most needs... and to be effective in telling me precisely what that was!!

> Wish those signals were as strong for everyone out there -- we might have a

> much healthier population if people knew how to read their own body's

> signals!

>

> Anyone know whether juice, dried (sugary - yum!) or canned chunks would be

> better sources, or are they all roughly the same? It doesn't appear as

> though bromelain is something that will ever be listed on food labels...

>

> Courtenay Schurman, CSCS

* Don't forget to sign all letters with full name and city of residence if

you wish them to be published!

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  • 1 year later...

Yes, Bromelain is an anti-inflamatory.

http://www.findarticles.com/cf_dls/m3741/11_47/57943516/p1/article.jh

tml

and for a long list of MEDLINE articles see:

http://www.bromelain.net/herbal-remedies/bromelain/research-on-

bromelain

We use it especially when taking antibiotics because it allows far

greater penetration into tissue of the antibiotics. We often have

taken up to 4000 GDU/DAY

Clinical Indications

Antitumor: Several studies, both animal and human, indicate

bromelain might have some antimetastatic ability.8-10 In doses of

over 1000 mg daily, bromelain has been combined with

chemotherapeutic agents such as 5-FU and vincristine, resulting in

tumor regression.8,11

Immune Modulation: Bromelain can induce cytokine production in human

peripheral blood mononuclear cells. Treatment leads to the

production of tumor necrosis factor-alpha, interleukin-1-beta, and

interleukin-6 in a time- and dose-dependent manner.12,13 Bromelain

has also been shown to remove T-cell CD44 molecules from lymphocytes

and to affect T-cell activation.14

Potentiation of Antibiotics: Antibiotic potentiation is one of the

primary uses of bromelain in several foreign countries. In humans,

some undetermined activity of bromelain has been documented to

increase blood and urine levels of antibiotics.17-19

Combined bromelain and antibiotic therapy has been shown to be more

effective than antibiotics alone in a variety of conditions

including pneumonia, bronchitis, cutaneous staphylococcus infection,

thrombophlebitis, cellulitis, pyelonephritis, perirectal and rectal

abscesses,20 and sinusitis.21

11. Nieper HA. A program for the treatment of cancer. Krebs

1974;6:124-127.

14. Munzig E, Eckert K, Harrach T, et al. Bromelain protease F9

reduces the CD44 mediated adhesion of human peripheral blood

lymphocytes to human umbilical vein endothelial cells. FEBS Lett

1995;351:215-218.

15. Klaue P, Dilbert G, Hinke G, et al. Tier-experimentelle

untersuchungen zur enzymatischen lokalbehandlung subdermaler

verbrennungen mit bromelain. Therapiewoche 1979;29:796-799.

16. Houck JC, Chang CM, Klein G. Isolation of an effective debriding

agent from the stems of pineapple plants. Int J Tissue React

1983;5:125-134.

17. Tinozzi S, Venegoni A. Effect of bromelain on serum and tissue

levels of Amoxycillin. Drugs Exptl Clin Res 1978;4:39-44.

18. Luerti M, Vignali ML. Influence of bromelain on penetration of

antibiotics in uterus, salpinx and ovary. Drugs Exp Clin Res

1978;4:45-48.

19. Renzinni G, Varengo M. The absorption of tetracycline in

combination with bromelain by oral application. Arzneim-Forsch

1972;22:410-412.

20. Neubauer RA. A plant protease for potentiation of and possible

replacement of antibiotics. Exp Med Surg 1961;19:143-160.

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  • 3 years later...
Guest guest

this sounds interesting, will have to check into it more and seewhat I can find. I am like you Ed will have to see about addingthis to hubby's list as well as mine.... thanks for the articleJudyinMO BromelainBromelain by E. Meinig, DDS, FACD http://www.price-pottenger.org/Articles/Bromelain.htm Bromelain was first introduced in 1957. Since then it has proved an important aid to so many diseases that more than 600 research articles are now found in the scientific literature about this product. It is a proteolytic enzyme, one that decomposes protein in the body. One of its first noted benefits was as a digestant. Bromelain is derived from the stem of the pineapple plant. This enzyme is effective not only in the acid present in the stomach, but also in the alkaline environment of the intestine It is considered a substitute for the digestants pepsin and tryptin. When I first became acquainted with it as a digestant, it didn't appear to be too effective. Since then, I have learned that patients were using too low a dosage. What will surprise you is the long list of diseases for which bromelain has proved helpful besides MSAL-digestion. Some of these are: angina, heart disease, rheumatoid arthritis, cellulitis, thrombophlebitis, surgical trauma, sports injuries, ecchymosis (black and blue areas), edema, pneumonia, scleroderma, sinusitis, shortens labor, and reduces appetite. Dr. Hans Nieper, world renowned physician, has had fabulous success in treating heart cases with bromelain, magnesium oratate, and potassium oratate. He reported this therapy was 95 percent successful in preventing heart attacks. Dr. Gordon in Sacramento, California, using the same regime, had 85 percent success. Nieper's mortality rate in the treatment of strokes and heart attacks is only 2 percent, while that of the Cleveland clinic in Ohio, using conventional therapies, was 21 percent, and that of a Rotterdam Holland clinic, 19 percent. Dr. Nieper also reported bromelain was slowly and steadily effective in lowering blood pressure and was "one of the most effective anti-arthritics" (ANAVIT-F3). It stops platelet aggregation --the stickiness of blood cells. His clinic since 1975 has found its ability to break up fibrin has reduced leg amputation cases of diabetics and cardiovascular disease patients to zero. Dentists who are familiar with these studies have been having wonderful success in reducing the swelling that occurs from wisdom tooth extractions and other oral surgical operations. There are many companies that have bromelain supplements on the market. The one used by Dr. Hans Nieper is called ANAVIT-F3. It is also the one used by most of the researchers. Originally only Hawaiian pineapple was used, but today it is also manufactured in Taiwan, Brazil and Puerto Rico. Naturally, some of these products vary in their constituents and action. Upon testing, many are found to have low stability and activity. Incidentally, most bromelain products contain only 100 to 125 mg. while ANAVIT-F3 capsules contain 230 mg. If one uses the usual recommended dose for ANAVIT-F3 of one capsule 4 X a day, it would be necessary to double that amount for most other products. Most producers of bromelain do not tell you that it becomes inactivated by heat. If kept in the refrigerator it will keep for 10 years.

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Guest guest

It is not just good for heart attacks; that in only one of the things it is good for. Many people seem to get 'sticky blood' - it is also sometimes called Disease. It causes strokes among other things. Bromelain is good for circulation by clearing the viens etc. This is good for those with pheripheral neuropathy, among others. I suspect it would also help with damaged muscled - they need as much oxygen and nutrients as possible in order to rebuild themselves.

blessings

Shan

PS Systemic Enzymes have been used for over 50 years in Europe to treat many conditions. I understand that there are over 300 papers on them.

Re: Bromelain

Posted by: "LARRY FOSTER" jaf11@...   judyinmo2000

Sun May 6, 2007 7:06 am (PST) this sounds interesting, will have to check into it more and see

what I can find. I am like you Ed will have to see about adding

this to hubby's list as well as mine.... thanks for the article

JudyinMO

Bromelain

Bromelain

by E. Meinig, DDS, FACD

http://www.price-pottenger.org/Articles/Bromelain.htm<http://www.price-pottenger.org/Articles/Bromelain.htm>

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Guest guest

Bromelian had been used for years. Here is what I know about it: 1) Should be taken on an empty stomach (It is a protein digesting enzyme) 2) Can be found active if one juices fresh COLD pineapple, canned pineapple juice has been pasteurized and the activity of the enzyme is ZERO. 3) Use to be available by prescription and was called ANANASE. Was removed due to suppose side effects. The biggest one being low profit to the drug companies. 4) If one has heart disease, this enzyme needs to be taken more than once a day. It prevents heart attacks and blood from clotting INSIDE a person. 5) If you can find it, get enteric coated tablets. AND KEEP IN FRIDGE

Ahhh...imagining that irresistible "new car" smell? Check out

new cars at Autos.

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Guest guest

I just called my local vitamin store and they carry this and

he said he always has it in stock for it is a HUGE seller.

This is the same store where I buy my Serrapeptase and the

owner of the store is very helpful telling me information on

anything I ask him about when I visit.

The price for the best on the market that he carries is $14.00

for a bottle of 60 count.

I asked what the customers are buying it for and they tell him

that it is excellent for digestive issues as well reduction of

inflammation. I told him about how it is being talked about on

this group site and he said that it makes sense that it would

be good for those with heart disease due to its ability to fight

inflammation.

I am definitely going to be buying some of this stuff.

Ed

>

> Bromelian had been used for years. Here is what I know about it:

>

> 1) Should be taken on an empty stomach (It is a protein digesting

enzyme)

>

> 2) Can be found active if one juices fresh COLD pineapple, canned

pineapple juice has been pasteurized and the activity of the enzyme is

ZERO.

>

> 3) Use to be available by prescription and was called ANANASE. Was

removed due to suppose side effects. The biggest one being low profit

to the drug companies.

>

> 4) If one has heart disease, this enzyme needs to be taken more

than once a day. It prevents heart attacks and blood from clotting

INSIDE a person.

>

> 5) If you can find it, get enteric coated tablets. AND KEEP IN FRIDGE

>

>

> ---------------------------------

> Ahhh...imagining that irresistible " new car " smell?

> Check outnew cars at Autos.

>

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Guest guest

Ed and group, I am going out tomorrow and get some as well.what I have read it sounds good. JudyinMO Re: BromelainI just called my local vitamin store and they carry this and he said he always has it in stock for it is a HUGE seller.This is the same store where I buy my Serrapeptase and theowner of the store is very helpful telling me information onanything I ask him about when I visit.The price for the best on the market that he carries is $14.00for a bottle of 60 count.I asked what the customers are buying it for and they tell himthat it is excellent for digestive issues as well reduction ofinflammation. I told him about how it is being talked about onthis group site and he said that it makes sense that it wouldbe good for those with heart disease due to its ability to fightinflammationI am definitely going to be buying some of this stuffEd>> Bromelian had been used for years. Here is what I know about it:> > 1) Should be taken on an empty stomach (It is a protein digestingenzyme)> > 2) Can be found active if one juices fresh COLD pineapple, cannedpineapple juice has been pasteurized and the activity of the enzyme isZERO.> > 3) Use to be available by prescription and was called ANANASE. Wasremoved due to suppose side effects. The biggest one being low profitto the drug companies.> > 4) If one has heart disease, this enzyme needs to be taken morethan once a day. It prevents heart attacks and blood from clottingINSIDE a person.> > 5) If you can find it, get enteric coated tablets. AND KEEP IN FRIDGE> > > ---------------------------------> Ahhh...imagining that irresistible "new car" smell?> Check outnew cars at Autos.>

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Guest guest

Hi Ed -- How much are you going to take a day? Do you take it between

meals or with meals? I think there is some interaction with aspirin and

some other things if taken at high doses. What does the bottle suggest per

day?

Noreen

Bromelain

I bought my first bottle of Bromelain today and just took

my first capsule.

The brand is NOW and is the highest potency there is with

2400 GDU - 500 mg.

If there are any side effects I will be sure and let you

know since I very insusceptible in noticing side effects.

Ed

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Guest guest

Ed, please do let us know.. I was reading some ofthe side effects... JudyinMO BromelainI bought my first bottle of Bromelain today and just took my first capsule.The brand is NOW and is the highest potency there is with2400 GDU - 500 mg.If there are any side effects I will be sure and let youknow since I very insusceptible in noticing side effects.Ed

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Guest guest

It is supposed to be taken on an empty stomach. I will get back

to the group and tell of any side effects next Wednesday (1 wk)

and let everyone know how I feel.

I am taking 1 capsule a day as directed on the label.

>

> Ed, please do let us know.. I was reading some of

> the side effects...

> JudyinMO

> Bromelain

>

>

> I bought my first bottle of Bromelain today and just took

> my first capsule.

>

> The brand is NOW and is the highest potency there is with

> 2400 GDU - 500 mg.

>

> If there are any side effects I will be sure and let you

> know since I very insusceptible in noticing side effects.

>

> Ed

>

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  • 2 years later...

Hi all, read a post on here today about the benefits of Bromelain for Carpet

Tunnel and Plantar Fasciitis - I have really bad PF - have had for years and

NEVER considered that it COULD be associated with thyroid issues!!

Therefore, I am very interested in peeps experience of this as a supplement to

help these conditions, can anyone tell me the brand names of Bromelain so I can

look out for it here in Thailand...

Incidentally, with having really bad PF in both heels I have now come across

'FitFlops' sandals which are just like flip flops but have a special sole that

relives the symptoms of PF and other things and they are my life saver and I can

now walk upright and straight and without pain - until I take them off - the

pain is still there but at least I can live a 'normal' life - I have two pairs

so far, one for indoors and the other pair for outdoors. They have just

launched their winter range of styles too. (I have no connection with this

company - just a VERY satisfied customer)

If anyone wants to explore FitFlops further see... http://www.fitflop.com

Meanwhile any info re the Bromelain would be SO appreciated... Many thanks -

Carol x

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