At last some test results but what do they mean?

[Guest guest]

My wife Gill has been Hypo with Hashimotos for 15 years and has been prescribed

Levothyroxine for all this time, though the dose has been changed. It is now

87.5mcg daily. It was decreased from 100mcg on 10th June after T4 was last

tested at 20.1 (9.0-19.0pmol/L) in May this year.

Gill has multiple symptoms including visual problems and some symptoms of Ocular

Myasthenia, and a confirmed diagnosis of Fibromyalgia.

Gill has the following antibodies:

ANA 320 >160

Anti DNA Native 192 >55

Anti ENA 2.8 ?

TgAb 180 >80

Gill has never had her T3 tested and Dr refused so she has obtained private

results:

Free T4 16.3 12.0-22.0pmol/L

Free T3 3.4 3.0-6.2pmol/L

TSH 5.2 0.4-4.0mIU/L

Oestradiol 18 up to 145pmol/L

Progesterone 1 not given for post menopause

Prior to this test her TSH has always been around 1 +/- 0.3

Does anyone know what is the cause of the high TSH and what next action should

be