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RE: Androstenedione level

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Hi - I expect by now your GP will have told you about low

Androstenedione. There is quite a lot on the Internet but very mostly very

technical. However, here is one possible explanation.

http://www.bmj.com/cgi/content/abstract/2/6096/1177

" Plasma androstenedione and oestrone concentrations were

measured in 72 postmenopasual women. The women included some who had

undergone oophorectomy, some with osteoporosis, and normal controls;

they were matched for years since menopause. Both hormone concentrations

were significantly reduced in the women with osteoporosis. The women

who had undergone oophorectomy had hormone concentrations intermediate

between the normal and osteoporotic values. Oestrogen deficiency

secondary to low androstenedione levels is a major risk factor in

postmenopausal osteoporosis, and may be caused by failure of ovarian

stromal androgen secretion or some abnormality in the

pituitary-adrenal axis. "

Luv - Sheila

Hi, I have received the list of tests from my

endo and there is one I have never heard of Androstenedione and my level 1.8

and reference range is 4.0 - 102 nmol/L so mine is very low anyone else had

this and had an explaination. I have my GP appointment today so will ask her

and am going to try and get a referral to see Dr. Shotliffe at Chelsea and

Westminster.

Thanks

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