Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 Hi Vicky, Do you mean more Bowel movements or less?...abdominal side effects are usually due to the latter but t3 itself dosent cause this! have you looked at the adrenals? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 Hi I meant slowed down bowel movements - sorry I should have specified. However, I will look at the adrenals info as my Daughter is also having Prednisolone for adrenal insufficiency. many thanks for your reply > > Hi Vicky, > > Do you mean more Bowel movements or less?...abdominal side effects are usually due to the latter but t3 itself dosent cause this! > > have you looked at the adrenals? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 Hi Vickyanne, Did your daughter's doctor consider using hydrocortisone for your daughter to maintain aspects of the ultradian rhythm (cortisol cycling). Prednisolone 'flattens' the steroid output profile. (recent paper by Lightman's group) best wishes Bob > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 http://www.nature.com/ncb/journal/v11/n9/abs/ncb1922.html this is it Jane, Bob > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 Jane, Just to clarify, your bowel movements have slowed due to the introduction of t3?what dose are you taking?are you taking this with any other thyroid meds?do you have any recent labs to show your free Ts on? Has your daughter been diagnosed with an adrenal problem? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 Most definitely Vicky and for the better. When I am on T4 alone I get constipation for several days then diarrhoea, then constipation, then diarrhoea and it stresses me out. As soon as I have some T3 my bowels are 100% normal. This I KNOW because it started happening when I started to go downhill on T4 alone. Nobody put it down to thyroid. I had all kinds of tests. Then because I was so ill with other thyroid symptoms, I went to private doctor who gave me T3. Didn't realise the bowels were back to normal until 5 years later doctor put me on T4 only again, and it all started again. Now I am back on some T3 (very small) it has been normal again. That is more than a co-incidence in my eyes. Lilian Has anybody ever experienced bowel/abdominal side effects whilst taking T3? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 Hi Lillian Many thanks for your input which I found very interesting and informative. Glad to hear that you had a good result with it. My Daughter has not been diagnosed with underactive thyroid as yet, she has to go back for another blood test for her thyroid in November. Although her TSH has been 8.62 last year (2008) and 7.88 (this year) endo is still not convinced it is her thyroid. She has practically all the symptoms of hypo. I must say that since she has been on cortisol replacement her TSH has gone down to 0.9. The endo said that sometimes when the adrenals are addressed then this can happen. I am still not convinced though and for this reason we have sought the help of Dr Peatfield and are awaiting results for the 24 hour thyroid test and candida. At this moment in time she taking 12.5 of T3 under the advice of Dr P and the first 2 days she couldn't believe how well she felt. Once again many thanks for your reply. Vickyanne > > Most definitely Vicky and for the better. > > When I am on T4 alone I get constipation for several days then diarrhoea, then constipation, then diarrhoea and it stresses me out. > > As soon as I have some T3 my bowels are 100% normal. > > This I KNOW because it started happening when I started to go downhill on T4 alone. Nobody put it down to thyroid. I had all kinds of tests. Then because I was so ill with other thyroid symptoms, I went to private doctor who gave me T3. Didn't realise the bowels were back to normal until 5 years later doctor put me on T4 only again, and it all started again. > > Now I am back on some T3 (very small) it has been normal again. > > That is more than a co-incidence in my eyes. > > Lilian > > Has anybody ever experienced bowel/abdominal side effects whilst taking T3? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 Hi Vickyanne, An ultradian rhythm is shorter than a day, in this case about two hourly rhythms. So-say, 'pulsatile' release of cortisol controls the transcription of other genes....so shorter term changes in the body can be accommodated. Prednisolone will cause continuous or a disturbed reaction(s) to what ought to be pulsatile release of those other proteins arising from cortisol-controlled processes. best wishes Bob > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2009 Report Share Posted October 21, 2009 hi Bob, Could you tell me more about Prednisolone. My daughter is prescribed this. I wonder if HC would be better for her. If I have the info then I can ask her doctor. Judy > > > Quote Link to comment Share on other sites More sharing options...
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