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Gilberts Syndrome/ high bilirubin levels

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You wrote:

>

> Mine is quite the opposite.

>

> Hypo on 150mcg thyroxine bilirubin was <2, euthyroid on 200mcg thyroxine

> bilirubin was 4.

If these are in umol/L rather than mg/DL, then the difference is not

significant. Total bilirubin normally ranges up to 17. Since it is

broken down by light, the difference could simply be the result of how

much time you spent outside that day.

Bilirubin is an excretory product from the break down of hemoglobin.

Consequently, a high level is not necessarily protective but an

indication that breakdown of heme is happening faster than excretion

through the bile and kidneys. It does seem to have anti-oxidant effects,

so there may be some benefit to slightly sluggish elimination. HypoT

would slow down both elimination channels.

Chuck

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Hi Chuck

Yes they are in umol/L.

Chris

/

>

>

> If these are in umol/L rather than mg/DL, then the difference is not

> significant. Total bilirubin normally ranges up to 17. Since it is

> broken down by light, the difference could simply be the result of how

> much time you spent outside that day.

> Chuck

>

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Chuck,

I have always wondered what happens to the T3 after getting into the cells.

With the constant creation of T3, it must go somewhere, some how. If that were

known, perhaps we could get a handle upon the usage of T3 rather than its

availability.

Have a great day,

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Hi

Prof Tom Scanlon (UCLA) did some work showing that 3-iodothyronamine

( a degradation product of T4/T3 ) can precisely reverse the effects of T3,

leading to an alternative (to RT3) explanation of the apparent inability of some

people to use either T4 or T3. It took some refined analytical techniques ( mass

spec ) to find this potent material.

Search on 'Scanlon T' for more recent work.

best wishes

Bob

>

> Chuck,

>

> I have always wondered what happens to the T3 after getting into the cells.

With the constant creation of T3, it must go somewhere, some how. If that were

known, perhaps we could get a handle upon the usage of T3 rather than its

availability.

>

> Have a great day,

>

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Bob,

You wrote:

> Prof Tom Scanlon (UCLA) did some work showing that 3-iodothyronamine

> ( a degradation product of T4/T3 ) can precisely reverse the effects of

> T3,...

Very interesting. Evidently the compound was discovered before 2001, but

Scanlon showed that the activity was in blocking T3. The short hand for

it is T1AM. There is also a T0AM. Note that the 3 refers to a ring

position, and not to the number of iodine atoms. It only has 1.

Chuck

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Didn't

you put this research in the FILES of this forum Bob. Can you point us to it

again?

Luv -

Sheila

Hi

Prof Tom Scanlon (UCLA) did some work showing that 3-iodothyronamine

( a degradation product of T4/T3 ) can precisely reverse the effects of T3,

leading to an alternative (to RT3) explanation of the apparent inability of

some people to use either T4 or T3. It took some refined analytical techniques

( mass spec ) to find this potent material.

Search on 'Scanlon T' for more recent work.

best wishes

Bob

>

> Chuck,

>

> I have always wondered what happens to the T3 after getting into the

cells. With the constant creation of T3, it must go somewhere, some how. If

that were known, perhaps we could get a handle upon the usage of T3 rather than

its availability.

>

> Have a great day,

>

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Link A Scanlan T1,T2 search.txtScanlan's papers T2,T1,T1AM, etc, on Pubmed

>> Didn't you put this research in the FILES of this forum Bob. Can you point> us to it again?> > > > Luv - Sheila> > Hi > > Prof Tom Scanlon (UCLA) did some work showing that 3-iodothyronamine > ( a degradation product of T4/T3 ) can precisely reverse the effects of T3,> leading to an alternative (to RT3) explanation of the apparent inability of> some people to use either T4 or T3. It took some refined analytical> techniques ( mass spec ) to find this potent material.> > Search on 'Scanlon T' for more recent work.> > best wishes> Bob

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Hi Bob,

This may go towards explaining why I need so much T3 to feel

well- most is being wasted!

Hi

Prof Tom Scanlon (UCLA) did some work showing that 3-iodothyronamine

( a degradation product of T4/T3 ) can precisely reverse the effects of

T3, leading to an alternative (to RT3) explanation of the apparent

inability of some people to use either T4 or T3.

best wishes

Bob

------------------------------------

TPA is not medically qualified. Consult with a qualified medical

practitioner before changing medication.

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