Anti-Thyroid Peroxidase Antibodies - from NHS pathology

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Anti-Thyroid Peroxidase Antibodies

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Container:

Serum - Red top

Reference Range:

Thyroid Peroxidase (TPO) < 100 IU/ml

Turnaround Time:

7 Working Days

Comments:

N/A

Clinical Information:

Anti-thyroid peroxidase antibodies at high titre are found in patients with Hashimoto's thyroiditis (95%); primary myxoedema (90%); Graves' disease (18%). (Anti-thyroglobulin antibodies also occur in these diseases, but are less sensitive and specific and are rarely measured).

Low titre anti-thyroid antibodies may occur in colloidal goitre, thyroid carcinoma, transiently in De Quervain's thyroiditis, in other organ-specific autoimmune diseases e.g. pernicious anaemia, 's disease & , rarely, in normal people.

Anti-thyroid antibodies may be predictive of future thyroid disease, therefore clinical and biochemical follow-up is advised.http://www.nhspathologyplus.fph.nhs.uk/Default/Immunology/Immunology_Tests_v1.0/Tests_A/Anti-Thyroid_Peroxidase_Antibodies.aspx