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pharmacoeconomic methods

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Dear members

Cost minimization analysis:

Example:

In a multicentric, pragmatic, randomized controlled trial, cerivastatin, a third generation statin, was compared with branded pravastatin for the treatment of adults with primary hypercholesterolemia, 5% of whom had a history of previous coronary artery disease that had failed to respond to a dietary intervention.

Primary care doctors involved in the study were told to prescribe doses and titration schedules according to their normal practice. The study randomized 417 patients to one of the two treatment options and followed them for one year, measuring for efficacy, safety and cost outcomes.

Tarun Wadhwa

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