Re: Acvances in nasal and pulmonary medicine delivery-CONCLUSION

[Guest guest]

Dear Members,

I am extremely thankful to Dr. Vijay sir for giving me an opportunity to

moderate this discussion on the NetRUM. I am especially thankful to Dr.

Surendra, Amit Panchal for their important contribution and also all NetRUM

members who took efforts to read all the posts of the discussion.

Various medicines are under investigation using nasal/pulmonary routes of

administration. These include small molecules, protein/ peptides, and genes,

etc. Pulmonary/ nasal medicine delivery offers great potential for both local

targeting for the treatment of respiratory diseases and systemic targeting for

the treatment of diabetes mellitus or thrombosis, tuberculosis, epilepsy, etc

and also for effective vaccination. Patients planning to use such delivery

methods, practical issues, such as the time needed for medicine delivery and the

size of the device will be most important to them. Cost is also an important

parameter since newer devices appear to cost more than the previous ones.

However, equally important parameters as cost are compliance with treatment and

quality of life. The less time these, mainly young, patients spend using a

nebulizer along with the ability to carry their medicine delivery system easily

makes their life as close to normal as

possible. This may counterbalance the increased cost paid for their treatment.

But this is not the case with poor patients in the developing economies. We

recognize the importance of quality of life, but the cost of the delivery system

must not be an obstacle to the treatment of patients, especially if clinical

effectiveness does not differ. It is a further object of the invention to

provide low cost and easy-to-use, maintenance free and more sophisticated

medicine delivery devices.

Regards,

Dr. Mangesh,

Nagpur.

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