Animal Toxicity Studies

[Guest guest]

Respected members,

Good morning. I am beginning my discussion on the topic ‘Animal Toxicity Studies’.

Animal Toxicity Studies may be defined as the tests of newer drugs done on animals to ensure their safety in human beings.

These include discovery of any unknown side effect, which in future may hamper the use of drug in humans.

This topic will be covered under following headings.

1. Need for toxicity tests

2. Requirements for undertaking toxicity tests

3. Types of toxicity tests

a. Systemic toxicity studies

b. Single dose

c. Repeated dose studies

d. Fertility tests

e. Teratogenecity

f. Local toxicity

g. Ocular toxicity

h. Inhalational toxicity

i. Genotoxicity

j. Carcinogenecity

4. Recent advances

Dr Somesh RayasamJR,Pharmacology dept,GMCH, Nagpur.