Re: Results of published studies

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Dear Friends,I'm astonished why this valuable debate has cropped up after long years of use of mercury containing dental amalgam.Thanks and regards Professor (Dr.) Ranabir Pal, M.D., D.C.H., M.B.A., FAIMER FELLOW Professor,Community Medicine Sikkim Manipal Institute of Medical Sciences (SMIMS) & Central Referral Hospital (CRH) Chairman, Board of Studies and Member, Research Advisory Committee 5thMile,Tadong, Gangtok, Sikkim, India – 737 102 Ph.No.+91- 3592- 270534/270294/231137, ext Residence) 335, (Hospital) 150 Fax:+91-3592-231496/231147/231162 Mobile: +91-9433247676 e-mail:ranabirmon@... From: smita sontakke <smitaavanti@...>Subject: Results of published studiesnetrum Date: Tuesday, 23 March, 2010, 10:43 PM

Friends,

Here are results of some studies which have tried to investigate the relationship between dental amalgam and health effects. WHO reports that "there may be no level of mercury at which some adverse effects do not occur" (WHO (2005) Mercury in Health Care)

.. A study conducted by measuring the intraoral vapor levels over a 24-hour period in patients with at least nine amalgam restorations showed the average daily dose of inhaled mercury vapor was 1.7 µg (range from 0.4 to 4.4 µg), which is approximately only 1% of the threshold limit value of 300 to 500 µg/day established by the WHO, based on a maximum allowable environmental level of 50 µg/day in the workplace. (Berglund, A (1990). "Estimation by

a 24-hour study of the daily dose of intra-oral mercury vapor inhaled after release from dental amalgam.". Journal of dental research 69 (10): 1646–51.) A Swedish study of autopsies examined the mercury levels in brains and kidneys and found a strong correlation with the number of amalgam fillings. A German study found that mercury urinary excretion was significantly higher in those with dental amalgam fillings. The NIDR Amalgam Study, performed on a cohort of an adult military population of 1127 healthy males, found that based on their cross-sectional data, it is estimated that, on average, each ten-surface increase in amalgam exposure is associated with an increase of 1 ug/L mercury in urine concentration. Peer-reviewed scientific studies have come to opposite conclusions on whether the mercury exposure from amalgam fillings causes health problems. A 2004 systematic review conducted by the Life Sciences Research Office, whose clients include the FDA and NIH, concluded that "the

current data are insufficient to support an association between mercury release from dental amalgam and the various complaints that have been attributed to this restoration material". Another review published in 2005 by the Freiburg University Institute for Environmental Medicine found that "mercury from dental amalgam may lead to nephrotoxicity,

neurobehavioural changes, autoimmunity, oxidative stress, autism, skin and mucosa alterations or non-specific symptoms and complaints", that "Alzheimer's

disease or multiple sclerosis has also been linked to low-dose mercury exposure", and that "removal of dental amalgam leads to permanent improvement of various chronic complaints in a relevant number of patients in various trials." In a smaller group of 85 patients who suffered from symptoms resembling Chronic Fatigue Syndrome and had their amalgams replaced with composites and metal-free ceramics, "over 78 percent reported improvement in health status as compared to the period prior to metal removal." Dr. Smita

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