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pharmacoeconomic methods

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Dear members

Key issues in conducting cost of illness studies:

Generalisability: The key question is: is the study generalisable to the situation of interest? It is important to pay careful attention to any inclusion or exclusion criteria used in such studies. The smaller the proportion of eligible patients who are included in the study and its analysis, the more concerned about the study’s representatives of its own parent population.

A commonly occurring situation is that patients from one or several clinics or hospitals are included in a study; often these are more research active centres, such as those affiliated with universities. But patients in such centres might be more severely ill than patients treated in smaller local centres because of selective referral of more severe cases.

Tarun Wadhwa

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