Guest guest Posted April 14, 2010 Report Share Posted April 14, 2010 Dear members,Nifedipine Mechanism of action:- • Calcium channels within the cell membranes of sperm. • Affects sperm function rather than production. • Produces a normal amount of sperm, and the sperm appear functional when viewed through a microscope. But in vitro tests show that these sperm cannot fertilize an egg.• Low levels of mannose lectin on the sperm cell membranes. • Physically prevent mannose lectins from moving to the surface of the cell membrane by stiffening the membrane with excess cholesterol  RegardsDr Sanjay Yallappa ChoudhariJR2,Dept of PharmacologyGMC, Nagpur Quote Link to comment Share on other sites More sharing options...
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