video on how HDAC inhibitors are thought to modify gene expression

[Guest guest]

A pretty good educational video on how HDAC inhibitors are thought to modify

gene expression of tumor cells.

http://www.pharmacyclics.com/wt/page/hdac

There are many such agents under investigation, and I think two that have

won recent approval for t-cell lymphomas.

As expected, the video has a promotional feel - featuring the company's

candidate drug. As always, results from clinical testing is what counts.

Even so-called targeted drugs will have affects on normal cells, leading to

side effects.

All the best,

~ Karl