Long-term calorie restriction is highly effective in reducing the risk for ather

[Guest guest]

Let us not lose focus!

" Serum total cholesterol (Tchol), low-density lipoprotein cholesterol,

ratio of Tchol to high-density lipoprotein cholesterol (HDL-C),

triglycerides, fasting glucose, fasting insulin, CRP, PDFG-AB, and

systolic and diastolic BP were all markedly lower, whereas HDL-C was

higher, in the CR than in the American diet group. Medical records

indicated that the CR group had serum lipid-lipoprotein and BP levels

in the usual range for individuals on typical American diets, and

similar to those of the comparison group, before they began CR.

Carotid artery IMT was & #8776;40% less in the CR group than in the

comparison group. Based on a range of risk factors, it appears that

long-term CR has a powerful protective effect against atherosclerosis.

This interpretation is supported by the finding of a low carotid

artery IMT. "

http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed & pubmedid=1509658\

1

[Guest guest]

It would be nice to know how much is directly related to CR and how much just due to weight loss that might occur with any diet.

The comparison group was 20 kg heavier. I wonder if they used a group where the weight was the same would there be the same diff?

Although it wouldn't be easy finding 50 yo's weighing 132 # in my county.

Regards.

Anthropometric characteristics

Characteristic

CR (n = 18)

Controls (n = 18)

P value

Age, years

50.3 ± 10

50.3 ± 11

0.988

Height, m

1.7 ± 0.1

1.8 ± 0.1

0.562

Weight, kg

59.5 ± 5.5

80.9 ± 8.8

0.0001

BMI, kg/m2 (men)

19.6 ± 1.9

25.9 ± 2.7

0.0001

Total body fat, % (men)

6.7 ± 4

22.4 ± 7

0.0001

Trunk fat, % (men)

3.4 ± 4

23.7 ± 9.2

0.0001

Lean mass, % (men)

93.3 ± 4

76.8 ± 7

0.0001

Regards

----- Original Message -----

From: drsusanforshey

Sent: Monday, June 20, 2005 5:15 PM

Subject: [ ] Long-term calorie restriction is highly effective in reducing the risk for ather

Let us not lose focus!"Serum total cholesterol (Tchol), low-density lipoprotein cholesterol,ratio of Tchol to high-density lipoprotein cholesterol (HDL-C),triglycerides, fasting glucose, fasting insulin, CRP, PDFG-AB, andsystolic and diastolic BP were all markedly lower, whereas HDL-C washigher, in the CR than in the American diet group. Medical recordsindicated that the CR group had serum lipid-lipoprotein and BP levelsin the usual range for individuals on typical American diets, andsimilar to those of the comparison group, before they began CR.Carotid artery IMT was & #8776;40% less in the CR group than in thecomparison group. Based on a range of risk factors, it appears thatlong-term CR has a powerful protective effect against atherosclerosis.This interpretation is supported by the finding of a low carotidartery IMT."http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed & pubmedid=15096581