Time to test CLL p53 function

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BlankTime to test CLL p53 function

Clive S. Zent

MAYO CLINIC

Chronic lymphocytic leukemia (CLL) patients with p53 pathway dysfunction have

poor responses to conventional chemoimmunotherapy and short survival. This small

but important cohort of CLL patients would benefit from early identification and

appropriate management. The challenge is to develop clinically useful tests of

p53 pathway function.

Full text

http://bloodjournal.hematologylibrary.org/cgi/content/full/115/21/4154?ct=ct

or http://bit.ly/9C7TbE