Zygomycosis Successfully Treated in CLL Patient

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Acta Biomed. 2006;77 Suppl 4:13-8.

Rhinoorbital and pulmonary zygomycosis post pulmonary aspergilloma

in a patient with chronic lymphocytic leukaemia.

Barr A, Nolan M, Grant W, Costello C, Petrou MA.

Department of Haematology, Chelsea and Westminster Hospital, London,

UK.

A patient with an 18-year history of chronic lymphocytic leukaemia

developed zygomycosis of the orbit, sinuses and nasal bones together

with pulmonary fungal nodes due to Absidia corymbifera while on high

dose steroids and four months after successful treatment of

pulmonary aspergilloma with liposomal amphotericin B followed by

oral voriconazole.

He was treated successfully with extensive surgical debridement,

intravenous liposomal amphotericin B and intravenous itraconazole.

PMID: 17370565 [PubMed - in process]