[Bilateral papilledema secondary to chronic lymphocytic leukaemia.]

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[bilateral papilledema secondary to chronic lymphocytic leukaemia.]

F Saenz-Frances, C Calvo-, J Reche-Frutos, J Donate-, E

Huelga-Zapico, J -, and J -Feijoo

Arch Soc Esp Oftalmol, May 1, 2007; 82(5): 303-6.

Servicio de Oftalmología, Hospital Clínico Universitario San , Madrid,

España.

CASE REPORT: We present the case of a 65-year-old man who was seen in the

casualty department complaining of bilateral visual loss. His past medical

history was unremarkable except for chronic lymphocytic leukaemia diagnosed two

years previously: he was no longer receiving treatment for this disorder. His

visual acuity was 20/200 in the right eye and 20/63 in the left eye and he had a

bilateral papilledema. Computed tomography and magnetic resonance imaging of the

brain and orbit were performed and showed an infiltrative mass in the orbit with

extension to the ethmoid bone and both optic nerves. Biopsy of the mass was

compatible with chronic lymphocytic leukaemia. DISCUSSION: Leukaemic

infiltration of the optic nerve and central nervous system is a rare

complication of chronic lymphocytic leukaemia, although it is common in the

acute forms of this disease. Optic nerve infiltration is the most important

ophthalmologic manifestation of leukaemia because it threatens vision and it is

treatable (Arch Soc Esp Oftalmol 2007; 82: 303-306).

PMID: 17516268