Guest guest Posted May 16, 2005 Report Share Posted May 16, 2005 shhhh..... JR -----Original Message----- From: [mailto: ]On Behalf Of Rodney Sent: Monday, May 16, 2005 11:53 AM Subject: [ ] Statins vs Cancer Hi folks: " ........... those taking statins had rates of breast, prostate and lung cancer that were 51 percent, 54 percent and 48 percent lower, respectively, than those who hadn't taken such drugs " . http://www.foxnews.com/story/0,2933,156646,00.html So. Should we all be taking statins of some kind? Rodney. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 16, 2005 Report Share Posted May 16, 2005 Sorry for the cryptic answer... We have seen these kinds of results before. Of course the drug companies want to merchandise statins for over the counter sales and have people pop them like vitamins. Just like aspirin is beneficial to people who have already had a heart attack, statins (also anti-inflammatory) surely have some general benefit to people who already have bad diet and lifestyle. There is such a thing as too low inflammation level, blood that is too thin, etc. The etiology of cancer is complex and multi-facetted. Energy restriction seems to be generally beneficial. Perhaps if a study of statin use in energy restricted mammals showed a benefit I would reconsider. JR -----Original Message----- From: [mailto: ]On Behalf Of Sent: Monday, May 16, 2005 12:13 PM Subject: RE: [ ] Statins vs Cancer shhhh..... JR -----Original Message----- From: [mailto: ]On Behalf Of Rodney Sent: Monday, May 16, 2005 11:53 AM Subject: [ ] Statins vs Cancer Hi folks: " ........... those taking statins had rates of breast, prostate and lung cancer that were 51 percent, 54 percent and 48 percent lower, respectively, than those who hadn't taken such drugs " . http://www.foxnews.com/story/0,2933,156646,00.html So. Should we all be taking statins of some kind? Rodney. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 16, 2005 Report Share Posted May 16, 2005 Not to argue the doubt in testing, but when do we accept the results on statins? I doubt we will see life extension testing that shows statins are better in non-sick people. Most of the test results - we have to infer a benefit, like inferring CR works in humans. Some believe in supps, fervently - take lotsa supps already. What's the diff? (rhet) Admittedly, I can't be sure anyone knows much about cancer. I doubt I'll get my doc to write a presc for a statin for cancer protection. Still the best guess I have is lotsa different fruits and veggies. Regards. ----- Original Message ----- From: Sent: Monday, May 16, 2005 1:04 PM Subject: RE: [ ] Statins vs Cancer Sorry for the cryptic answer... We have seen these kinds of results before. Ofcourse the drug companies want to merchandise statins for over the counter salesand have people pop them like vitamins.Just like aspirin is beneficial to people who have already had a heart attack, statins(also anti-inflammatory) surely have some general benefit to people who already havebad diet and lifestyle.There is such a thing as too low inflammation level, blood that is too thin, etc.The etiology of cancer is complex and multi-facetted. Energy restriction seems tobe generally beneficial. Perhaps if a study of statin use in energy restricted mammalsshowed a benefit I would reconsider.JR -----Original Message-----From: [mailto: ]On Behalf Of Sent: Monday, May 16, 2005 12:13 PM Subject: RE: [ ] Statins vs Cancer Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 16, 2005 Report Share Posted May 16, 2005 You might actually get yer doc ta write such a prescription (statins for prevention of cancer). Also, there's also those offshore vendors if you are truly motivated. On 5/16/05, jwwright <jwwright@...> wrote: Not to argue the doubt in testing, but when do we accept the results on statins? I doubt we will see life extension testing that shows statins are better in non-sick people. Most of the test results - we have to infer a benefit, like inferring CR works in humans. Some believe in supps, fervently - take lotsa supps already. What's the diff? (rhet) Admittedly, I can't be sure anyone knows much about cancer. I doubt I'll get my doc to write a presc for a statin for cancer protection. Still the best guess I have is lotsa different fruits and veggies. Regards. ----- Original Message ----- From: Sent: Monday, May 16, 2005 1:04 PM Subject: RE: [ ] Statins vs Cancer Sorry for the cryptic answer... We have seen these kinds of results before. Ofcourse the drug companies want to merchandise statins for over the counter salesand have people pop them like vitamins. Just like aspirin is beneficial to people who have already had a heart attack, statins(also anti-inflammatory) surely have some general benefit to people who already havebad diet and lifestyle.There is such a thing as too low inflammation level, blood that is too thin, etc. The etiology of cancer is complex and multi-facetted. Energy restriction seems tobe generally beneficial. Perhaps if a study of statin use in energy restricted mammalsshowed a benefit I would reconsider. JR -----Original Message-----From: [mailto: ]On Behalf Of Sent: Monday, May 16, 2005 12:13 PM Subject: RE: [ ] Statins vs Cancer Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 17, 2005 Report Share Posted May 17, 2005 --- Al Pater <old542000@...> wrote: > --- Rodney <perspect1111@...> wrote: > > Hi folks: > > > > " ........... those taking statins had rates of breast, prostate and > > lung cancer that were 51 percent, 54 percent and 48 percent lower, > > respectively, than those who hadn't taken such drugs " . > > > > http://www.foxnews.com/story/0,2933,156646,00.html > > > > So. Should we all be taking statins of some kind? > > Hi All, > > Maybe not. See the below introduction to another aspect of lowering prostate > cancer > via lower sex hormones on cognition. It and the accompanying article referred to > in > the above are pdf-available papers. Sex hormones decrease with CR often, also. Hi All, Sorry am I , here it is: Salminen EK, Portin RI, Koskinen AI, Helenius HY, Nurmi MJ. Estradiol and cognition during androgen deprivation in men with prostate carcinoma. Cancer. 2005 Apr 1;103(7):1381-7. PMID: 15717315 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\ ct & list_uids=15717315 Prostate carcinoma has become the most common male treatment target in radiation oncology. To improve the outcome, androgen deprivation (AD) is increasingly used as neoadjuvant treatment. Recognition of adverse effects caused by hormonal manipulation in prostate carcinoma is important, because castration levels of testosterone are known to affect several organ systems, and the quality of life may significantly deteriorate during AD.[1][2] Significant associations between serum estradiol and cognition have been suggested to exist among men, although the associations appear weaker when compared with women.[3] Estradiol regulates the neuronal structure and synaptic connectivity in the adult as well as the developing brain,[4] and, of the sex hormones, estradiol may be the critical factor affecting some cognitive domains, as androgenic steroids are aromatized to estrogens locally in the brain.[5][6] Estrogen receptors are found in several brain areas, including the hypothalamus, the preoptic area, the anterior pituitary, and the CA1 region of the hippocampus.[4] They are colocalized with testosterone receptors in the areas essential for learning and memory.[7] The functions of estrogen in the brain include modulation of neurotransmitters, reorganization of synapses, or prolonged survival of neurons, as well as prevention of cerebral ischemia, and alterations in lipoproteins.[8] A protective role of estradiol for verbal memory has been suggested in several studies,[3][9][10] but also contradictory links have been reported.[11][12] The hypothalamus and anterior pituitary areas are targets of therapeutic manipulation with luteinizing hormone releasing hormone (LHRH) analogs in prostate carcinoma, the aim being to induce androgen deprivation by interrupting hormonal regulation and testicular testosterone production. Earlier studies have suggested associations between testosterone decline and some cognitive performances, such as cognitive slowing, attention, and memory.[1][13][14] The connection with estradiol decline is less well established. The authors of the current study hypothesized that AD therapy induces estradiol decline, with an impact on cognitive performances, and, therefore, the authors conducted a prospective study with newly diagnosed prostate carcinoma patients. Al Pater, PhD; email: old542000@... Stay connected, organized, and protected. Take the tour: http://tour.mail./mailtour.html Quote Link to comment Share on other sites More sharing options...
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