Reversible renal insufficiency secondary to extrinsic splenic compression of the kidney in a patient with chronic lymphocytic leukemia

[Guest guest]

Blank Reversible renal insufficiency secondary to extrinsic splenic compression

of the kidney in a patient with chronic lymphocytic leukemia.

M Hadj-Moussa and JA Brown

ScientificWorldJournal, January 1, 2010; 10: 796-8.

Medical College of Georgia, Augusta, GA, USA. mhadjmou@...

While increased renal venous and direct renal parenchymal pressure may

cause renal insufficiency, there are no prior reports of hypersplenism secondary

to chronic lymphocytic leukemia (CLL) doing so. This first report of massive

splenomegaly leading to marked compression of the left kidney associated with

renal insufficiency that resolved after splenectomy illustrates that profound

extrinsic renal compression from splenomegaly may significantly compromise left

renal function and splenectomy should be considered in this situation.

PMID: 20454760