Acid suppressive therapy increases risk of pneumonia

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" Our results suggest that acid-suppressive drugs such as H2RAs and PPIs

are associated with an increased risk of community-acquired pneumonia,

probably because of reduction of gastric acid secretion, facilitating

oral infections, " the authors write. " To avoid the calculated excess

pneumonia, patients with asthma or chronic obstructive lung disease,

immunocompromised persons, children, and elderly persons should be

treated with acid-suppressive drugs only when necessary and with the

lowest possible dose. "

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http://www.medscape.com/viewarticle/492096