Guest guest Posted January 9, 2009 Report Share Posted January 9, 2009 what do you all think ??go look at www.HopeMD.com and read rest of his articles this is so interesting. My Dr thinks it came from my two wrecks I had in 1994 and in 1999. heidi The question of what causes fibromyalgia is foremost in many of our minds. But the answer is fairly simple: WE DO NOT KNOW. It does seem that fibro begins with some trauma to the system. This can be physical-many people can trace the onset of their illness to an auto accident, fall, or other physical trauma. It can be infectious-the flu, mono, Lyme's disease, etc. And it may be psychological-loss of a loved one, divorce, verbal (and certainly physical) abuse. It is as if a significant trauma starts a vicious circle. We respond with a fight or flight response. This, and the pain we experience, affects our balance of neurotransmitters-the chemicals that transmit nerve impulses in the nervous system. Substance P, a pain modulator, increases in the central nervous system. However, rather than going back to normal as the trauma subsides it stays elevated. Other neurotransmitters (NTs), such as serotonin, norepinephrine and dopamine, may be affected as well. This imbalance makes us extra- sensitive to pain. Thus the vicious circle. Trauma/pain –> NT imbalance –> increased sensitivity to pain –> further NT imbalance –> more pain and so on. So while we have ideas about what happens biochemically in fibro, CFS, and chronic pain we still have not answered the question…what causes it to begin with? For many of us who suffer from fibro and, in fact, many of the other " invisible illnesses " this is very frustrating. We believe that if we can find the cause then we can find the cure. This is not really true. Western medicine does not really have answers to this question for most chronic illnesses. So what do we do? We treat the symptoms. If you have pain we treat you with pain medications. If you cannot sleep we give you a medication for that. We try to bring the neurotransmitters back into balance. Thus anti-depressants to boost serotonin and norepinephrine (Cymbalta being the latest-Elavil- amitryptalline-being one of the first and still very useful). We try to regulate substance P and other pain modulators (Lyrica may work in this area-we are not entirely sure of it's mechanism). Therefore, if we could answer the question " What cause fibromyalgia (and for that matter the other invisible illnesses) how would we benefit? How would it change our treatment? Could it help us get well again? Quote Link to comment Share on other sites More sharing options...
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