Guest guest Posted February 21, 2010 Report Share Posted February 21, 2010 Hi Mike, You shall have no problems with flax seed, guarantied. With kind regards, Slavek. them4 wrote: > > > > Hi all, > > i'm just wondering if anyone here has used flax seedin there diet > while doing the beck protocol? or taken Vit C? > > I'm eliminating all other supplements but am wondering if it would be > ok to have these dietary supplments taken while doing the protocol? > > any suggestions would be most appreciated, t > > thankyou for your time > > mike > them4@... > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 21, 2010 Report Share Posted February 21, 2010 HI slavek. Yes i was just wondering because the video with eliazar ben joseph was saying not to have garlic as i guess it is a blood thinner. i'm not sure about flax seed because it might lower your cholesterol. certainly it is just a dietary supplment. How often do you use the complete beck protocol for? do you do it as bob beck suggests and do it for 4 weeks at least once or twice a year. ? best regards Mike them4@... Re: FLAX SEED-VIT C Hi Mike,You shall have no problems with flax seed, guarantied.With kind regards, Slavek.them4 wrote:> > > > Hi all,> > i'm just wondering if anyone here has used flax seedin there diet> while doing the beck protocol? or taken Vit C?> > I'm eliminating all other supplements but am wondering if it would be> ok to have these dietary supplments taken while doing the protocol?> > any suggestions would be most appreciated, t> > thankyou for your time> > mike> them4telus (DOT) net> > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 21, 2010 Report Share Posted February 21, 2010 I had flax seed oil every morning on my cereal during the protocol. Why? I didnt have vit C. I think that was recommended not to take. Multivits are recommended after magnetic pulsing Nick > > Hi all, > > i'm just wondering if anyone here has used flax seedin there diet while doing the beck protocol? or taken Vit C? > > I'm eliminating all other supplements but am wondering if it would be ok to have these dietary supplments taken while doing the protocol? > > any suggestions would be most appreciated, t > > thankyou for your time > > mike > them4@... > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 21, 2010 Report Share Posted February 21, 2010 Hi Mike, Contrary to some purists here, I am a dirty old man and such tell the truth and nothing but truth and the whole truth whatever it may be worth to anyone. I have stared Beck protocol on 9 Jan 2010. Never heard of it before mid December 2009 with Sota instrument equipment, i.e. silver pulsar and magnetic pulsar. I do blood electrification as specified near full blast religiously twice a day for between 70-80 minutes per session. I use the magnetic pulsar concurrently on two spots of my body and use it as a rough timer for my electrification sessions. When I am through two mag. pulsar time-outs, each 30 mins, I push silver pulsar fair bit longer. I brew silver tea with the silver pulsar in one liter batches stored in dark whiskey bottles. I do not drink ozonated water, but diluted 35% hydrogen peroxide, averaging 30 drops of peroxide a day, but going up still. I do not shy away from garlic, or any other spices although I do not use as much as I used to, which is more due to my diet changes than my conscious limiting of it. Same goes for onions. I am also a smoker and smoke some 12-16 cigarettes a day. I am also a coffee addict and drink some two coffees a day, used to be much more, but I do not have sex all that often G. I slap magnesium chloride on my upper torso every day to build up magnesium level in me and I have been doing that since september 2009. I use MMS1 / DMSO on my lower legs and on my scalp about 1-2 a week to keep fungi away. I have actually done a number on it in the summer with MMS, but the damaged toenails get reinfected when I stop for more than 2 weeks. I slap it on my head to do the same, keep fungi away. I also swallow about 65 mg of iodine in form of Lugol about every other week with two pills of selenium, just to keep tabs on these wide spread deficiencies. I have severely cut down on intake of starches in my diet and I have cut out milk products almost entirely and processed vegetable oils absolutely. I eat meat much less then before June 2009 when I decided to be my own doctor, but I do not stick to any superstitions about beef and pork, even though I usually go for a fish. So far, Beck protocol has not addressed my major issue, that is a chronic abdominal pain, which does not originate in the digestive tract, or any specific internal organs. It appears to be something in the peritoneal cavity among all these organs. It started as an apparent infection some 6 years ago and has been with me ever since. Drs. are lost. My second pressing problem was and still is a bit what is turning out to be uric acid deposits in my hamstrings, with occasional flare up of inflammation in toes. This is actually where coffee comes into the picture. I am increasing my intake as of today since I found out two days ago that coffee is the best dietary control for this crap. So, I am going to be on around 4 cups [more like mugs] of coffee now. The tow problem actually started last July, when I dropped my coffee intake from some 8 coffees a day to 1. My third pressing problem is a ridiculous creepy crawly twitchy feeling in my calves and feet, which abated on a long water fast last fall for about 5 weeks, but came beck and is still with me. Whatever that is. I also have what I call bankers blood [that is when your red blood cells stack up like coins, rather than being dispersed through the plasma] full of fungi and bacteria. At least that was the ugly picture still on 22 December 2009. Next check is just at the beginning of March, so I shall see what happened there. My fourth pressing problem is a ceramic gall bladder. The thing is somewhat shrunk, its walls thickened and calcified, which is most likely not a subject to be addressed by the blood electrification. My fifth problem is my wife, but I do not expect the Beck protocol to sort that one out either. The above list of problems is actually much shorter than it was in June 2009 and I will in due time get rid of it entirely, or die doing it :-) Anyway. So far on the positive side: It appears more and more that I am growing hair on my head where there was none 2 months ago. Nothing spectacular, but it is there. Magnetic pulsar is a definite help relieving almost constant discomfort in my gall bladder area. A pet wart of mine on my finger is slowly, but steadily shrinking. My abdominal pains may be abating, but not quite sure as they were never quite steady. Will that do? With kind regards, Slavek. P.S. I was about to drop Beck silver pulsar in favor of Godzila, but I have realized that I better have a thorough look to see that I know what I am going into and do it right. So, I am still on Beck as of today and probably tomorrow. Then we shall see, as I am getting Godzila sorted out right now to my satisfaction. them4 wrote: > > > > HI slavek. > > Yes i was just wondering because the video with eliazar ben joseph was > saying not to have garlic as i guess it is a blood thinner. i'm not > sure about flax seed because it might lower your cholesterol. > certainly it is just a dietary supplment. > > How often do you use the complete beck protocol for? do you do it as > bob beck suggests and do it for 4 weeks at least once or twice a year. > ? > > best regards > > Mike > them4@... > > > > > > > Re: FLAX SEED-VIT C > > > > Hi Mike, > > You shall have no problems with flax seed, guarantied. > > With kind regards, Slavek. > > them4 wrote: > > > > > > > > Hi all, > > > > i'm just wondering if anyone here has used flax seedin > there diet > > while doing the beck protocol? or taken Vit C? > > > > I'm eliminating all other supplements but am wondering if > it would be > > ok to have these dietary supplments taken while doing the > protocol? > > > > any suggestions would be most appreciated, t > > > > thankyou for your time > > > > mike > > them4@... > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2010 Report Share Posted February 22, 2010 I take 1 Table spoon of Brown Flax Seed a day All Ground up and blend it with 2 oz Wheat grass juice, water, Ice and a Banana & sometimes also Blueberry. Great smoothie and it dropped my Cholesterol count 125 points! Hey BG! Great info! The Off topic comment of the Healthy Type are alway welcome to me. Ron nixatnite wrote: I had flax seed oil every morning on my cereal during the protocol. Why? I didnt have vit C. I think that was recommended not to take. Multivits are recommended after magnetic pulsing Nick > > Hi all, > > i'm just wondering if anyone here has used flax seedin there diet while doing the beck protocol? or taken Vit C? > > I'm eliminating all other supplements but am wondering if it would be ok to have these dietary supplments taken while doing the protocol? > > any suggestions would be most appreciated, t > > thankyou for your time > > mike > them4@... > No virus found in this outgoing messageChecked by PC Tools AntiVirus (6.1.0.25 - 6.14390).http://www.pctools.com/free-antivirus/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2010 Report Share Posted February 22, 2010 how is that wheat grass juice , how does it taste? I take 2tablespoons ground up flax in my cereal lately in the morning ,I heard 2 tbsp was the recommended dose. but if 1 works save your money and take one.It sure gets the bowels working good wich might help in the elimintation of all the waste from zapping. ??? i'm only guessing. mike Re: Re: FLAX SEED-VIT C I take 1 Table spoon of Brown Flax Seed a day All Ground up and blend it with 2 oz Wheat grass juice, water, Ice and a Banana & sometimes also Blueberry. Great smoothie and it dropped my Cholesterol count 125 points! Hey BG!Great info! The Off topic comment of the Healthy Type are alway welcome to me.Ronnixatnite wrote: I had flax seed oil every morning on my cereal during the protocol. Why? I didnt have vit C. I think that was recommended not to take.Multivits are recommended after magnetic pulsing Nick>> Hi all, > > i'm just wondering if anyone here has used flax seedin there diet while doing the beck protocol? or taken Vit C?> > I'm eliminating all other supplements but am wondering if it would be ok to have these dietary supplments taken while doing the protocol? > > any suggestions would be most appreciated, t> > thankyou for your time> > mike> them4@...>No virus found in this outgoing messageChecked by PC Tools AntiVirus (6.1.0.25 - 6.14390).http://www.pctools.com/free-antivirus/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2010 Report Share Posted February 22, 2010 The wheat grass Juice itself is a Bit Strong & sweet to the taste. Some do it a Shot but I prefer it in a smoothie with all the other goodies for Breakfast. Ron them4 wrote: how is that wheat grass juice , how does it taste? I take 2tablespoons ground up flax in my cereal lately in the morning ,I heard 2 tbsp was the recommended dose. but if 1 works save your money and take one.It sure gets the bowels working good wich might help in the elimintation of all the waste from zapping. ??? i'm only guessing. mike ----- Original Message ----- From: Ron To: Sent: Monday, February 22, 2010 6:42 AM Subject: Re: Re: FLAX SEED-VIT C I take 1 Table spoon of Brown Flax Seed a day All Ground up and blend it with 2 oz Wheat grass juice, water, Ice and a Banana & sometimes also Blueberry. Great smoothie and it dropped my Cholesterol count 125 points! Hey BG! Great info! The Off topic comment of the Healthy Type are alway welcome to me. Ron nixatnite wrote: I had flax seed oil every morning on my cereal during the protocol. Why? I didnt have vit C. I think that was recommended not to take. Multivits are recommended after magnetic pulsing Nick > > Hi all, > > i'm just wondering if anyone here has used flax seedin there diet while doing the beck protocol? or taken Vit C? > > I'm eliminating all other supplements but am wondering if it would be ok to have these dietary supplments taken while doing the protocol? > > any suggestions would be most appreciated, t > > thankyou for your time > > mike > them4@... > No virus found in this outgoing message Checked by PC Tools AntiVirus (6.1.0.25 - 6.14390). http://www.pctools.com/free-antivirus/ No virus found in this outgoing messageChecked by PC Tools AntiVirus (6.1.0.25 - 6.14410).http://www.pctools.com/free-antivirus/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2010 Report Share Posted February 22, 2010 thanks for the iput slavek, i'll respond throughout your message with @@@ Re: FLAX SEED-VIT C> > > > Hi Mike,> > You shall have no problems with flax seed, guarantied.> > With kind regards, Slavek.> > them4 wrote:> >> >> >> > Hi all,> >> > i'm just wondering if anyone here has used flax seedin> there diet> > while doing the beck protocol? or taken Vit C?> >> > I'm eliminating all other supplements but am wondering if> it would be> > ok to have these dietary supplments taken while doing the> protocol?> >> > any suggestions would be most appreciated, t> >> > thankyou for your time> >> > mike> > them4telus (DOT) net> >> >> >> >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2010 Report Share Posted February 22, 2010 Hi Mike, I will snip and go in between as well. them4 wrote: > @@@ why do you see yourself as being dirty??? Because I am no purist in anything :-) > @@@ i have had all the equipment for almost 2yrs and have > only really used the protocol fully once for about 2weeks. > So i'm quite a newby as well to this. I personally do not endorse an idea that a specific duration of any treatment is applicable to all across the board. This is something one has to sort out for him/herself. There are infections which may take a long time, because they are hidden away where it takes a long time for any remedy to get, if at all. Then keeping the rest of the body clean at all times is the process allowing the own immune system to do the actual cleaning of such hideaways. > @@@ i heard to do the magpulsing before blood > electrification was good as the mag pulser dumps toxic > matter into the blood stream. Oh well. It probably is the case, but I see no reason to not do both at the same time, especially since I over stretch the silver pulsar over the mag pulsar. > how much do you ingest of the colloidal silver daily? Nowadays ~ 0.4 l = about 0.42 US quart > @@@wow, how is the hydrogen peroxide for you? that is potent > stuff. I have absolutely no ill effects from my 18 drops (35%) per glass of water, 2 glasses a day as of now. I am still going up though. > @@@I guess the whole idea with garlic is that it thins your > blood out, and to further zap i guess thins it out more and > as the zappping and electroporietion may amplify the > strength of the garlic 5x more First of all, electroporation is not really the cause of the conflicts while on Beck. What comes into the picture is electropotentiation of the substances as well as of the blood cells. It changes the " electron " reactivities. I have no idea where Bob Beck got his take on Garlic, but I have not found any reference which would corroborate it and my personal experience does not confirm it. This is not to say that such may not happen to others. > @@@how did you discover you were deficient in magnesium, > were you tense all the time?generally magnesium is to help > relax. and tons of other stuff. I had a fairly pronounced issues with cramping, " restless leg " and muscle twitching all over. Done some homework, found out this was a deficiency right across North America, Marcus Sircus stands out on that, and bought my first bottle of the magnesium oil. > @@@i have discovered that pork you have to cook it really > well if you are going to eat it as it carries worms. but i > guess so do other meats. That would be something my mama has pressed on me when I was a kid. The Czech kitchen is actually oriented on well cooked meats, with the exception of beef. But that one may be tricky in today's world as well due to the chemical content. I would have to do a huge research and eating even beef well cooked is means less hassle. > @@@ Have you ever tried castor oil packs on your abdomen, > that would help you heal the unhealable. I actually do not try much. I collect information, check it, make my decision and do it. So far so good. I am aware of the packs, but I prefer to stick to as few procedures concurrently as much as I can, to help me to sort out what does, or does not do. > @@@ coffee is very acid forming in the body, it could be > that when you lowered your intake your body was trying to > get rid of all the acid, I doubt that. I have missed to bookmark this. It is probably copyrighted, but the source is included, so be it. -------- High uric acid levels in the blood are a precursor of gout, the most common inflammatory arthritis in adult men. It is believed that coffee and tea consumption may affect uric acid levels but only one study has been conducted to date. A new large-scale study published in the June 2007 issue of Arthritis Care & Research examined the relationship between coffee, tea, caffeine intake, and uric acid levels and found that coffee consumption is associated with lower uric acid levels but that this appears to be due to components other than caffeine. Coffee is one of the most widely consumed beverages in the world; more than 50 percent of Americans drink it at the average rate of 2 cups per day. Because of this widespread consumption, its potential effects have important implications for public and individual health. Led by Hyon K. Choi, of the University of British Columbia in Vancouver, Canada, the current study was based on the U.S. Third National Health and Nutrition Examination Survey, conducted between 1988 and 1994. It included over 14,000 men and women at least 20 years old who consented to a medical exam in which blood and urine specimens were obtained. Coffee and tea consumption were determined based on responses to a food questionnaire that assessed intake over the previous month. Researchers estimated the amount of caffeine per cup of coffee or tea using data from the U.S. Department of Agriculture. The results showed that levels of uric acid in the blood significantly decreased with increasing coffee intake, but not with tea intake. In addition, there was no association between total caffeine intake from beverages and uric acid levels. These results were similar to those found in the only previous study on the topic, which was conducted in Japan. Interestingly, there was an association between decaffeinated coffee consumption and uric acid levels. " These findings suggest that components of coffee other than caffeine contribute to the observed inverse association between coffee intake and uric acid levels, " the researchers state. A recent study found that coffee was associated lower C peptide levels (a marker of insulin levels). The researchers in the current study suggest that because there is a strong relationship between insulin resistance and elevated uric acid levels, the decreased insulin levels associated with coffee consumption may lead to lower uric acid levels. Coffee is also a major source of chlorogenic acid, a strong antioxidant, which may improve insulin sensitivity. Chlorogenic acid also helps inhibit glucose absorption in the intestine; in another study decaffeinated coffee seemed to delay intestinal absorption of glucose and increase concentrations of glucagon-like peptide 1, which is well known for its beneficial effects on insulin secretion and action. The researchers note further that their results could be due to an effect of non-caffeine components found in coffee, which would also explain why coffee affected uric acid levels but tea did not. Notes: Article: " Coffee, Tea, and Caffeine Consumption and Serum Uric Acid Level: The Third National Health and Nutrition Examination Survey, " Hyon K. Choi, Curhan, Arthritis Care & Research, June 2007; 57:5; (DOI: 10.1002/art.22762). Contact: Amy Molnar Wiley & Sons, Inc. -------- > have you tried taking apple cider > vinegar daily that is pretty good to heal alot of interall > issues. apparently.balancing your ph. 2tsp in a glass of > water with honey 1-2 times aday. I actually alkalize with baking soda when pressed hard. > @@@that is funny you mention this , i have this same problem > in my calves, i can actually look at them and sometimes see > them twitch. i believe it is parasites or worms. need to get > on some parasite cleanses internally, > > zapping won't take care of all the internal things alone, > you need herbs i believe. take black walnut > ,cloves,wormwood, combo. Well Mike, if it is parasitic, as I suspect it is, Godzila is more than likely to get it, when I get to it. Why would I want to throw my good money into trying this and that, probably for insufficient period of time, as most folks do, rather than find the best, universal treatment and do it quite thoroughly? But I do keep these in my back pocket. Black walnut is common here and the season is approaching to get my own, fresh and free and I am aware of its properties as per Hulda information. > @@@ Look into Grapefruit Seed Extract for the fungal issues, > it has helped me. is a good safe natural antibiotic. Again, I prefer to do one thingie. As far as I can tell, electrification beats anything else right across the board, as long as it is done right and for peanuts. But it requires education and dedication. > @@@try the casto oil packs daily for a month on your liver > gall bladder area, have you done a liver flush before??? I have done no liver flash, because of the ceramic gall bladder. I have not found any info yet, which would deal with this combination. If, by any chance, there is a big stone in that pouch, hidden from ultrasound by the thick and calcified walls of the gall bladder, I might be in for a nasty surprise. No, thank you. > @@@Have you tried EFT, emotional freedom technique, look > into it people are talking about this one. Hehehe. Cheer up. Actually, if anything, I'd go for TF (total freedom) if anything, without trying. > @@@People like you usually get better, Just have to keep on > keeping on. Best of health to you, Mike, I have to. I have lot of things I still want to do in my life. One of them is to get at least few people to get hold of their own affairs as well, health being the most important one. > appreciate your comments. As I do yours. > may god bless. With kind regards, Slavek. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2010 Report Share Posted March 7, 2010 Int J Med Sci 2010; 7:29-35 ©Ivyspring International Publisher Research Paper Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action Bok Y. Lee1 ✉, Noori AL-Waili2, Dean Stubbs3, Wendell4, Glenn 5, Thia AL-Waili6, Ali AL-Waili7 1. Professor, Department of Surgery, New York Medical College, Valhalla, New York and Research Director, Life Support Technology Group, Mount Vernon Hospital, Sound Shore Health System, Mount Vernon, New York;2. Clinical Research Director, Life Support Technology Group, Mount Vernon Hospital, Sound Shore Health System, Mount Vernon, New York;3. Medical Director, BodiHealth Technology, North Tamborine QLD, Australia;4. CEO and Director, American Institute of Regeneration, Simi Valley, California, Mt. Tamborine QLD, Australia;5. CEO and Research Coordinator, Life Support Technology Group, Mount Vernon Hospital, Sound Shore Health System, Mount Vernon, New York;6. American Global University of Medical School, Belize;7. York College, Queens, New York. How to cite this article:Lee BY, AL-Waili N, Stubbs D, Wendell K, G, AL-Waili T, AL-Waili A. Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action. Int J Med Sci 2010; 7:29-35. Available from http://www.medsci.org/v07p0029.htm Abstract Oxidative stress plays a major role in the pathogenesis of both types of diabetes mellitus and cardiovascular diseases including hypertension. The low levels of antioxidants accompanied by raised levels of markers of free radical damage play a major role in delaying wound healing. Ultra-low microcurrent presumably has an antioxidant effect, and it was shown to accelerate wound healing. The purpose of the study is to investigate the efficacy of ultra-low microcurrent delivered by the Electro Pressure Regeneration Therapy (EPRT) device (EPRT Technologies-USA, Simi Valley, CA) in the management of diabetes, hypertension and chronic wounds. The EPRT device is an electrical device that sends a pulsating stream of electrons in a relatively low concentration throughout the body. The device is noninvasive and delivers electrical currents that mimic the endogenous electric energy of the human body. It is a rechargeable battery-operated device that delivers a direct current (maximum of 3 milliAmperes) of one polarity for 11.5 minutes, which then switched to the opposite polarity for another 11.5 minutes. The resulting cycle time is approximately 23min or 0.000732 Hz and delivers a square wave bipolar current with a voltage ranging from 5V up to a maximum of 40 V. The device produces a current range of 3 mA down to 100 nA. Twelve patients with long standing diabetes, hypertension and unhealed wounds were treated with EPRT. The patients were treated approximately for 3.5 h/day/5 days a week. Assessment of ulcer was based on scale used by National Pressure Ulcer Advisory Panel Consensus Development Conference. Patients were followed-up with daily measurement of blood pressure and blood glucose level, and their requirement for medications was recorded. Treatment continued from 2-4 months according to their response. Results showed that diabetes mellitus and hypertension were well controlled after using this device, and their wounds were markedly healed (30-100%). The patients either reduced their medication or completely stopped after the course of treatment. No side effects were reported. The mechanism of action was discussed. Keywords: Diabetes mellitus, hypertension, wound, ultra-low microcurrent Introduction Top IntroductionPatients and methodsDiscussionReferences Diabetes mellitus and cardiovascular diseases are challenging medical and social problems. Patients with diabetes mellitus are at a higher risk of developing vascular dysfunction and hypertension. The real etiology of these diseases is not well understood. However, cumulative evidence suggests that oxidative stress may play a key role in the development of diseases. It has been found that oxidative stress is associated with several cardiovascular diseases, including atherosclerosis, hypertension, heart failure, stroke, and diabetes, and plays a fundamental role in endothelial dysfunction associated with these diseases (1-6). Further, oxidative stress plays a major role in the pathogenesis of both types of diabetes mellitus. High levels of free radicals and the decline of antioxidant defense mechanisms lead to damage of cellular organelles and enzymes, increased lipid peroxidation, and development of insulin resistance (7). The vascular and systemic complications in diabetes are associated with hyperglycemia-induced overproduction of reactive oxygen species (8,9). Other studies showed that overproduction of reactive oxygen and nitrogen species, lowered antioxidant defense and alterations of enzymatic pathways in humans with poorly controlled diabetes mellitus can contribute to endothelial, vascular and neurovascular dysfunction (10). Insulin resistance is associated with reduced intracellular antioxidant defense, and therefore diabetic patients may have a defective intracellular antioxidant response that causes diabetic complications (11-13). The combination of the low levels of antioxidants and raised levels of free radical play a major role in delaying wound healing in aged rate and diabetic rats (14). It has been found that chronic leg ulcers contain localized oxidative stress (15). The recent finding revealed that insulin resistance is associated in humans with reduced intracellular antioxidant (11). Interestingly, antioxidants improve insulin sensitivity and help in wound healing (16,17). Along with others, the investigators have used microcurrent for treatment of chronic wounds and ulcers (18-20). In an earlier work, The Electro Pressure Regeneration Therapy (EPRT) device which produces a current range of 3 mA down to 100 nA, was used for treatment of chronic wounds and ulcers associated with chronic disease (21). The device used in the experiment was supposed to deliver electrons to tissues and then saturated free radicals with required electrons. The actual tissue regeneration, along with concomitant improvement noted in the general condition of the patient, points to a highly potent antioxidant effect on local tissues, as well as on tissues in general. This reduces free radicals and might facilitate tissue repair. This device is used as a model to deliver electrons to the body, including mitochondria and presumably working as an antioxidatant device. It was thought reasonable to use on patients with diabetes mellitus, hypertension and chronic wounds, to test whether delivering electrons to the body might help eliminate underlying oxidative stress, stabilize mitochondria and prevent further formation of excess free radicals. Patients and methods Top IntroductionPatients and methodsDiscussionReferences Electro Pressure Regeneration Therapy Device The EPRT device is an electrical device that sends a pulsating stream of electrons in a relatively low concentration throughout the body. The device is noninvasive and delivers electrical currents that mimic the endogenous electric energy of the human body. It is a rechargeable battery-operated device that delivers a direct current (maximum of 3 milliAmperes) of one polarity for 11.5 minutes, which then switched to the opposite polarity for another 11.5 minutes. The device was designed to switch the direction of current flow halfway through the cycle. The resulting cycle time is approximately 23min or 0.000732 Hz and delivers a square wave bipolar current with a voltage ranging from 5V up to a maximum of 40 V. The device produces a current range of 3 mA down to 100 nA. Electrodes are applied in 2 layers, and tap water is used as the conducting medium. The wraps cover a large surface area, thus reducing resistance and allowing an optimum number of electrons to flow freely into tissues. Patients and treatments Case 1: The first patient was a 74 year old female with poorly controlled non-insulin- dependent diabetes, hypertension, and hypercholesterolemia. She was seen with vomiting, diarrhea and gangrene of second toe on left foot. Two weeks prior to admission, the patient had sustained fall in the bathroom resulting in a left ankle fracture with vomiting and diarrhea for seven days. The patient was treated with metformin and augmentin. Upon examination, the patient was afebrile with stable vital signs, and femoral pulses were present bilaterally. Popliteal and pedal pulses were absent bilaterally with poor capillary refill. The left foot was red and inflamed up to and including the medial malleolus. The lateral aspect of the great toe and second toe turned black. Laboratory investigation revealed elevated blood glucose (17.9 mmol/L) and hyponatremia (Na+ 128 mEg/L). The patient underwent a medial forefoot amputation as part of her management. Within 28 days after surgery, the 4th and 5th toes become discolored, dusky purple and black. The patient also developed a large blood blister over her heel. Vascular opinion was for a below knee amputation. The patient was self- discharged against medical advice. The patient was started on treatment by Electro Pressure Regeneration Therapy device (EPRT) while she was in hospital. She continued daily treatments on the EPRT device at home, along with a diabetic diet. The left foot continued to improve and heal, and her remaining gangrenous toes eventually fell off. Her blood pressure at admission was 166/53 with use of Lisinopril, which was dropped and eventually ceased as her BP continued to drop; 146/68, 129/64, 144/67 in second, third and fourth weeks after treatment, and to 128/66 during 6th to 8th weeks post-treatment while the patient was on no medication. Her blood sugar was improved and HbA1c was dropped from 9.8 before treatment to 7.6, 6.5, 5.9 and 5.5 during 9 months after commencement of treatment. The patient eventually stopped diabetic and hypertensive medications. To date her HbA1c remains below 6 on diet alone. Case 2: The second patient was a 65 year old male with a long history of non insulin dependent diabetes and hypertension. Diabetic neuropathy had affected his feet and he could not feel the shoe rubbing. A small superficial ulcer developed on his 5th toe which became infected and subsequently, the 5th toe was amputated. His condition rapidly deteriorated and he developed necrotizing fasciitis and osteomyelitis. Consequently, he had surgery removing tendons, skin and the capsular linings of joints from his right foot. The patient was discharged after ten weeks in hospital with a large, infected, open wound requiring community nurses to do wound management. The patient was treated by the Electro Pressure Regeneration Therapy device; the wound was healed completely without further management and the diabetes was well controlled. HbA1c dropped from 7.3 to 6.6 after treatment. His blood pressure was 202/99 before the treatment, which was dropped to 155/73 after two weeks. His blood pressure continued within normal range with the use of the Electro Pressure Regeneration Therapy device 2-3 times weekly. Case 3: A 70 year old female was diagnosed with hypertension, epilepsy osteoarthritis and rheumatoid arthritis. Her blood pressure was 147/84 which was dropped to 138/72 three weeks after the treatment with the Electro Pressure Regeneration Therapy device. She continued using the EPRT device twice weekly and her blood pressure was under control without the use of antihypertensive medications. Case 4: A 77 year old female with hypertension, hypercholesterolemia, hypothyroidism, and type 2 diabetes (NIDDM) was treated with the Electro Pressure Regeneration Therapy device. Her blood pressure before treatment was 158/81 which was dropped to 125/65 after 1 week. Her blood pressure continued to be normal with use of the EPRT device despite discontinuation of antihypertensive medications. HbA1c was 7.8 before treatment which decreased to 6.9 and continued to be low during one year follow-up. Case 5: A 67 year old female with hypertension and osteoarthritis was treated with the Electro Pressure Regeneration Therapy device. Her blood pressure was 157/91 which dropped to 149/86 after 3 weeks. Case 6: A 70 year old female with hypertension, fibromyalgia, hepatitis, hypercholesterolemia, tuberculosis and a stroke was treated with the Electro Pressure Regeneration Therapy device for her hypertension. Her blood pressure was 134/84 before treatment which was dropped to 117/73 within 4 weeks after treatment despite discontinuation of her antihypertensive medication. Case 7: A 75 year old female with hypertension and benign postural vertigo was treated with the Electro Pressure Regeneration Therapy device. Her blood pressure was 157/86 before treatment, which was dropped to 138/76 and continued within normal limits while receiving one treatment per week. Case 8: A 53 year old female with type 1 diabetes (IDDM) from the age of 12, suffered renal failure as a result of her diabetes and underwent a kidney and pancreatic transplant in 1994. She also has hypercholesterolemia, left ventricular failure, renal failure and a history of a coronary artery bypass graft. She then started treatment with the Electro Pressure Regeneration Therapy device. While she is not considered to currently have diabetes her HbA1c dropped over the time period she was receiving treatments from 5.4 to 5.1. This was matched by her Blood Sugar Level (BSL) which also stabilized while she was receiving treatment over this period of time. Case 9: A 32 year old female with type 1 diabetes (IDDM) and no other concurrent health problems was treated with the Electro Pressure Regeneration Therapy device. She received 8 treatments over a two week period. HbA1c before treatment was 8.1 and was dropped to 7.1 after treatment. Her insulin requirement was also reduced. Case 10: A 59 year old female with type 2 diabetes (NIDDM), hypertension, fibromyalgia, chronic active hepatitis, and Bowens disease was treated with the Electro Pressure Regeneration Therapy device. Her blood sugar was normalized and HbA1c dropped from 7.2 to 6.3 after the treatment. Her HbA1c showed a slight increase to 6.4 within three months after therapy was discontinued. Case 11: A 70 year old female with type 2 diabetes (NIDDM), osteoarthritis, chronic pain and multiple operations was treated with the Electro Pressure Regeneration Therapy device. Her average Blood Sugar Level (BSL) before treatment was 9.8, and dropped to 7.4 and 7.1 after three and six months of treatment. She was treated twice weekly with the EPRT device. Case 12: A 68 year old male with type 2 diabetes (NIDDM), hypertension, stroke, chronic pain and polio was treated with the Electro Pressure Regeneration Therapy device. HbA1c before treatment was 7.8, which was dropped to 6.6 during treatment. He was treated three times per week most weeks during a six month period. Upon discontinuation of therapy HbA1c increased to 7.8. Discussion Top IntroductionPatients and methodsDiscussionReferences The results of this preliminary trial showed that ultra-low microcurrent has apparent therapeutic effects on diabetes, hypertension and wound healing. Presumably, one of mechanisms of action is its antioxidant activity. The action of EPRT is to produce electrical pressure rather than an electrical jolt as produced by a Transcutaneous Electrical Nerve Stimulator. Whereas Transcutaneous Electrical Nerve Stimulator device can produce a current varying from 1uA to 100 mA, the EPRT ranges from 100 nA to 3 mA. Moreover, Transcutaneous Electrical Nerve Stimulator frequency range is from 0.5 to 40,000 Hz with a range of cycle times from 2 seconds to 0.025 milliseconds. The EPRT has a frequency of approximately 0.000732Hz which gives a frequency time of 22.77 minutes. Namely, Transcutaneous Electrical Nerve Stimulator with power of 10 mA and a frequency of 1 Hz is delivering approximately 6x10 (14) electrons per cycle. As the cycle is 1 second all these electrons were delivered in that period as a jolt. The EPRT at a setting of 100 nA is delivering 8.129x10 (14) per cycle. But as this amount is being delivered over a 23 minute period (at rate of 6x10 (11) electrons per second) this behaves as a pressure instead of a jolt. This steady stream of electrons is what makes the EPRT a super antioxidant and not only does this correct malalignments in the cells electrical system but it also eliminates free radicals and then stimulates the mitochondria to produce ATP. Microcurrent has been successfully used to enhance soft tissue healing and to treat fracture nonunion (22,23). Microcurrent relieves myocontracture and can enhance conventional rehabilitation programs for children with cerebral palsy (24). Studies from the 1980s suggest that microcurrent therapy is effective at relieving the side effects of radiation therapy (25). The investigators have found that direct electrical therapy was effective in healing gum abscess and accelerated wound healing (20). Substances that increase electrical field, such as prostaglandin E2, enhance the wound healing rate and increase cell division (26-28). Electrical fields stimulate secretion of growth factor (28). Low mA current stimulates adenosine triphosphate production (26). It is discovered in another study that microcurrent stimulates dermal fibroblasts and U937 cells to secrete transforming growth factor-β1, a major regulator of cell-mediated inflammation and tissue regeneration (29). Insulin resistance plays a major role in the development of several metabolic abnormalities and diseases such as type 2 diabetes mellitus, obesity and the metabolic syndrome (30). In these conditions there is an elevation of both glucose and free fatty acid levels in the blood and an increase in oxidative stress (30,31). The high degree of oxidative stress might have an important role in decreasing insulin responsiveness (31-33). Many studies have suggested that ß-cell dysfunction results from prolonged exposure to high glucose and elevated free fatty levels (33). High glucose concentrations induce mitochondrial reactive oxygen species, which suppresses the first phase of glucose-induced insulin secretion (34). ß-cells are particularly sensitive to reactive oxygen species because they are low in antioxidant enzymes such as catalase, glutathione peroxidase, and superoxide dismutase (35). Therefore, the oxidative stress might damage mitochondria and markedly blunt insulin secretion (34). Recent studies suggested that ß-cell lipotoxicity is enhanced by concurrent hyperglycemia and that oxidative stress may be the mediator (36,37). An increase in insulin, free fatty acid, and/or glucose levels can increase reactive oxygen species production and oxidative stress, as well as activate stress-sensitive pathways (33). Many studies show that postprandial hyperglycemia is associated with oxidative stress generation (38). Repeated exposure to hyperglycemia and increased levels of free fatty acid can lead to ß-cell dysfunction that may become irreversible over time. It has been suggested that oxidative stress might be the mediator of damage to cellular components of insulin production (33,39). A major source of cellular reactive oxygen species is mitochondria, whose dysfunction contributes to pathological conditions such as vascular complications of diabetes, neurodegenerative diseases and cellular senescence (40-45). Source of reactive oxygen species in insulin secreting pancreatic β-cells and cells that are targets for insulin action is considered to be the mitochondrial electron transport chain. Hyperglycemia and lipotoxicity in obesity and related disorders are associated with mitochondrial dysfunction and oxidative stress (46,47). Oxidative stress-induced activation of NF-κB signaling might be associated with the pathogenesis of insulin resistance and type 2 diabetes (48-51). In obesity and type 2 diabetes it has been reported that antioxidants and IKK-B inhibitors protect against insulin resistance (52,53). Data show that increased lipid peroxidation in NIDDM has implications for vascular disease in diabetes (54). Oxidative stress plays an important role in the pathogenesis of cardiovascular diseases including hypertension (55). Clinical studies suggest the occurrence of increased reactive oxygen species production in humans with essential hypertension (56,57). Oxidative stress is considered to be a unifying mechanism for hypertension and atherosclerosis (58,59). Oxygen free radicals play a major role in the failure of ischemic wound healing, while antioxidants partly improve the healing in ischemic skin wounds (60). Oxygen free radicals mediate the inhibition of wound healing following ischemia-reperfusion and sepsis (61). It seems that diabetes mellitus, cardiovascular disease, such as hypertension, and delayed wound healing have a common important basic pathogenesis, which is related to imbalance between free radical production and removal. The use of ultra-low microcurrent might help in stabilizing mitochondria, working as antioxidants and therefore, enhancing normal function of β-cells and vascular tissue. Several clinical trials have demonstrated that treatment with vitamin E, vitamin C, or glutathione improves insulin sensitivity in insulin-resistant individuals (16,62). The acute effects of hyperglycemia-dependent endothelial cells dysfunction are counterbalanced by antioxidants (63-65). But clinical trials with antioxidants, in particular with vitamin E, have failed to show any beneficial effect (66). However, antioxidant therapy with vitamin E or other antioxidants is limited to scavenging already formed oxidants and may be considered symptomatic instead of a causal treatment for oxidative stress (67). Interruption of the overproduction of superoxide by the mitochondrial electron transport chain would normalize the pathways involved in the development of the oxidative stress (68). If our findings are proven by further studies involving a larger number of patients, ultra-low microcurrent therapy might change the concept of management of chronic disease. Conclusively, oxidative stress and oxidative damage to tissues are common pathology of chronic diseases, and using antioxidants, such as the EPRT device used in this experiment, might change the concept of management of chronic diseases. 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