White House: Lesser bird flu may be here

[Guest guest]

White House: Lesser bird flu may be here By LAURAN NEERGAARD, AP

Medical Writer Mon Aug 14, 7:52 PM ET

WASHINGTON - Scientists have discovered possible bird flu in two wild

swans on the shore of Lake Erie — but it does not appear to be the

much-feared Asian strain that has ravaged poultry and killed at least

138 people elsewhere in the world.

It will take up to two weeks to confirm whether the seemingly healthy

wild mute swans in Michigan really harbored the H5N1 virus or not.

On Monday, the Agriculture Department declared that initial testing

had ruled out the so-called highly pathogenic version of H5N1 — but

that they could have a relatively harmless, low-grade H5N1 strain

instead.

That's the suspicion, making Monday's announcement almost a practice

run for the day the more worrisome Asian strain actually arrives.

" This is not the highly pathogenic avian influenza virus that has

spread through much of other parts of the world, " said Ron DeHaven,

administrator of USDA's Animal and Plant Health Inspection Service,

adding, " We do not believe this virus represents a risk to human

health. "

Monday's announcement was the first reported hit from a massive new

program to test up to 100,000 wild birds in an effort to catch the

deadly Asian H5N1 virus if it does wing its way to North America,

something the government thinks could happen this year.

Were the highly pathogenic H5N1 to be found in any wild birds here,

that could trigger additional security steps to prevent infection of

commercial poultry flocks, and even more intensive monitoring.

Wild birds, especially waterfowl, are flu's natural reservoir — they

carry a multitude of influenza viruses. Sometimes, those strains jump

species, and if it's a flu virus very different from one people have

experienced before, a worldwide epidemic could result.

That's why scientists have closely tracked the virulent H5N1 strain

since it began its global march in late 2003. It is blamed for the

death or destruction of millions of birds overseas. Virtually all the

people who have caught it did so from close contact with infected

birds or their droppings. But scientists worry that the virus

eventually could mutate to become easily spread from person to person.

Last week, the government expanded the bird-testing program to

encompass the entire nation, after initial sampling mostly in Alaska.

Twenty mute swans from a Monroe County, Mich., game area were among

the first new batches of tests — because, coincidentally, they were

part of a state program to lower overcrowding of the nonnative

species. That testing found the possibility of H5N1 in two of the

swans.

Initial genetic testing ruled out the deadly Asian strain. In fact,

USDA said the virus' genes suggest that it is similar to a low-grade

North American version of H5N1, a virus found here in wild ducks in

1975 and 1986 and on a Michigan turkey farm in 2003. Another similar

version was detected last year in Canada, and scientists have thought

it probably common in wild birds — but didn't have the testing to

prove it.

" This is no surprise, " DeHaven stressed.

Plus, all the swans appeared healthy, a good signal, he added. The

virulent form of H5N1 usually rapidly sickens birds.

So why Monday's announcement? To be open about all this testing,

DeHaven said. And even low-pathogenic H5N1 requires monitoring,

because it has the potential to mutate into the more virulent form,

he added.

More important, " It was a real good test run of the system, " Dr.

Willie , director of the Michigan State University laboratory

where the initial testing was done, told The Associated Press.

Flu strains are named for two proteins that stud the virus' surface.

There are 16 known hemagglutinin versions, the " H, " and nine

neuramindases, the " N. "

Michigan State's initial screening tests searched for the presence of

H5 or H7, two variants that can signal signs of concern in birds. On

Friday, 's lab alerted USDA's confirmatory laboratory in Ames,

Iowa, that it had found H5 in the two swans.

Over the weekend, more testing at Ames found the N1 protein. That

doesn't necessarily mean the swans harbored the H5N1 strain; they

could have carried two different flu strains at once, say an H5N2 and

an H6N1.

That's a lot of science-speak to say stay tuned: It will take up to

two weeks to sort out exactly what the swans had, and to make sure it

was a low-pathogen version — by injecting baby chicks with the swans'

virus to see if they die.

http://news./s/ap/20060814/ap_on_he_me/bird_flu_13