Guest guest Posted March 21, 2003 Report Share Posted March 21, 2003 Osteoclasts are not 'evil' bone demolishers, they have a proper function and that is to recycle bone cells. Estrogen limits their biological functionality much like it does to other cell structures. The theories regarding this estrogen/osteoclast/osteoporosis relationship is absurd. The consideration of estrogen exposure risk and purposeful exposure to damage osteoclasts is equally absurd. I realize this must be frustrating for you so I apologize if my condradictory opinion makes this more difficult for you. DMM --- In , " Evely " <je@h...> wrote: > I am only 27 years old ... I have osteoporosis because I had a brain tumor > that crushed my pituitary gland so I never produced adequate estrogen for my > bones.... > now I have to weigh the risks with taking hormone replacement and possibly > getting other female cancers (breast cancer, ovarian cancer etc.) > > Estrogen stops bone loss in response to the activity of the parathyroid > hormones (PTH) > -Hormones from your parathyroid stimulate the osteoclasts > Osteoclasts are little cells that migrate through the bone and sniff > out areas where there is old bone. Bone that was made 10 years ago. And they > find those areas and they dissolve them away... kind of like pacman in the > arcades- pacman comes in and eats up the old bone. .... And they leave a > little space called a lacuna, a > little lake - a little emptiness . > > The osteoclasts are the bone demolishing cells on your " bone construction > crews " > Estrogen is what controls this parathyroid growth activity... when someone > does not have enough estrogen these parathyroid hormones begin to run wild > and break down too much bone > > taken from a book I'm reading called " Preventing Osteoporosis " by > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 21, 2003 Report Share Posted March 21, 2003 so you are saying I don't need to replace the estrogen I've lost?? ----- Original Message ----- From: " Dr. Marasco " <mmarasco@...> < > Sent: Friday, March 21, 2003 2:26 PM Subject: Re: osteoporosis estrogen > Osteoclasts are not 'evil' bone demolishers, they have a > proper function and that is to recycle bone cells. Estrogen limits > their biological functionality much like it does to other cell > structures. The theories regarding this > estrogen/osteoclast/osteoporosis relationship is absurd. > The consideration of estrogen exposure risk and purposeful exposure > to damage osteoclasts is equally absurd. > > I realize this must be frustrating for you so I apologize if my > condradictory opinion makes this more difficult for you. > > DMM > > > > > I am only 27 years old ... I have osteoporosis because I had a > brain tumor > > that crushed my pituitary gland so I never produced adequate > estrogen for my > > bones.... > > now I have to weigh the risks with taking hormone replacement and > possibly > > getting other female cancers (breast cancer, ovarian cancer etc.) > > > > Estrogen stops bone loss in response to the activity of the > parathyroid > > hormones (PTH) > > -Hormones from your parathyroid stimulate the osteoclasts > > Osteoclasts are little cells that migrate through the bone and > sniff > > out areas where there is old bone. Bone that was made 10 years > ago. And they > > find those areas and they dissolve them away... kind of like > pacman in the > > arcades- pacman comes in and eats up the old bone. .... And they > leave a > > little space called a lacuna, a > > little lake - a little emptiness . > > > > The osteoclasts are the bone demolishing cells on your " bone > construction > > crews " > > Estrogen is what controls this parathyroid growth activity... when > someone > > does not have enough estrogen these parathyroid hormones begin to > run wild > > and break down too much bone > > > > taken from a book I'm reading called " Preventing Osteoporosis " by > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 21, 2003 Report Share Posted March 21, 2003 my friend posted this ..... I don't want to end up like her mother This issue of the symptoms going away is bullshit. I have known a number of women who stopped HRT because of these fears and propaganda, and all the hot flashes, insomnia, etc came back. My mother who went thru menopause in her 30's always refused HRT because it scared her. She was still having terrible hot flashes (numerous times each day so her clothes would be wet) at 84 when she died. And she had horrible osteoporosis, bent over with the " dowager's hump, " and lots of pain. Her mother did too, even worse. ----- Original Message ----- From: " Dr. Marasco " <mmarasco@...> < > Sent: Friday, March 21, 2003 2:26 PM Subject: Re: osteoporosis estrogen > Osteoclasts are not 'evil' bone demolishers, they have a > proper function and that is to recycle bone cells. Estrogen limits > their biological functionality much like it does to other cell > structures. The theories regarding this > estrogen/osteoclast/osteoporosis relationship is absurd. > The consideration of estrogen exposure risk and purposeful exposure > to damage osteoclasts is equally absurd. > > I realize this must be frustrating for you so I apologize if my > condradictory opinion makes this more difficult for you. > > DMM > > > > > I am only 27 years old ... I have osteoporosis because I had a > brain tumor > > that crushed my pituitary gland so I never produced adequate > estrogen for my > > bones.... > > now I have to weigh the risks with taking hormone replacement and > possibly > > getting other female cancers (breast cancer, ovarian cancer etc.) > > > > Estrogen stops bone loss in response to the activity of the > parathyroid > > hormones (PTH) > > -Hormones from your parathyroid stimulate the osteoclasts > > Osteoclasts are little cells that migrate through the bone and > sniff > > out areas where there is old bone. Bone that was made 10 years > ago. And they > > find those areas and they dissolve them away... kind of like > pacman in the > > arcades- pacman comes in and eats up the old bone. .... And they > leave a > > little space called a lacuna, a > > little lake - a little emptiness . > > > > The osteoclasts are the bone demolishing cells on your " bone > construction > > crews " > > Estrogen is what controls this parathyroid growth activity... when > someone > > does not have enough estrogen these parathyroid hormones begin to > run wild > > and break down too much bone > > > > taken from a book I'm reading called " Preventing Osteoporosis " by > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 22, 2003 Report Share Posted March 22, 2003 On the subject of hormones and in particular estrogen, I trust biochemist Ray Peat above any other source. (See his site www.efn.org/~raypeat/ and especially www.efn.org/~raypeat/horm.html). I get his newsletter and he frequently discusses the " downsides " of estrogen and the many, many virtues of progesterone. I have seen sources other than Peat suggest that supplementing with progesterone (*instead* of estrogen) will help with osteoporosis as well as menopause symptoms. Peat tends to view estrogen as, at best, a necessary evil and not something you would want to raise the levels of with supplements. Peat patented one form of oral progesterone (in Vitamin E oil), Progest-E; it's available from Dr. Mike's site www.cedarcanyonclinic.com or from here: www.nutri-meds.com/progest- e.htm. Ray Peat's views are often at odds with the mainstream, but I think he knows his stuff. (As an aside, he's also a big proponent of coconut oil!) Appropriate Vitamin D (whether supplemental, or just sunshine exposure) will help with osteoporosis too; just calcium alone is not much help. I think Mercola (www.mercola.com) had something about this recently. Also, see http://www.lef.org/whatshot/#lssv --- In , " Evely " <je@h...> wrote: > I am only 27 years old ... I have osteoporosis because I had a brain tumor > that crushed my pituitary gland so I never produced adequate estrogen for my > bones.... > now I have to weigh the risks with taking hormone replacement and possibly > getting other female cancers (breast cancer, ovarian cancer etc.) > > Estrogen stops bone loss in response to the activity of the parathyroid > hormones (PTH) > -Hormones from your parathyroid stimulate the osteoclasts > Osteoclasts are little cells that migrate through the bone and sniff > out areas where there is old bone. Bone that was made 10 years ago. And they > find those areas and they dissolve them away... kind of like pacman in the > arcades- pacman comes in and eats up the old bone. .... And they leave a > little space called a lacuna, a > little lake - a little emptiness . > > The osteoclasts are the bone demolishing cells on your " bone construction > crews " > Estrogen is what controls this parathyroid growth activity... when someone > does not have enough estrogen these parathyroid hormones begin to run wild > and break down too much bone > > taken from a book I'm reading called " Preventing Osteoporosis " by > Quote Link to comment Share on other sites More sharing options...
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