Guest guest Posted December 15, 2003 Report Share Posted December 15, 2003 http://www.cmtnews.com/drugs-vitamins-dietary%20supplements/Drugs%20and%20weakne\ ss.html 4. There are drugs that cause weakness by a mechanism unrelated to worsening of neuropathy. The best example of this is Lipitor (and other tatin drugs used to lower blood cholesterol). In rare instances they cause muscle damage and therefore could make a CMT patient worse even though the effect is not on the nerve itself. With these drugs, it depends on the balance of risks. A patient with a very high cholesterol is at increased risk of death or disability from stroke or heart attack and this risk can be reduced with statins. However, if the cholesterol can be reduced through diet and exercise (not easy in CMT patients because of their difficulty exercising) then it would obviously be preferable to using a statin. 5. There are drugs that probably do cause a clinically significant neuropathy but only rarely and in certain susceptible individuals. Again, an example of this would be the statins (such as Lipitor). Gareth J. Parry MD Neurologist, Auckland Hospital Professor of Neurology, University of Minnesota Quote Link to comment Share on other sites More sharing options...
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