Guest guest Posted July 25, 2003 Report Share Posted July 25, 2003 There have been times in my life I have been vitamin B6 and B12 deficient. It was necessary for me to have injections and maintain vitamin therapy so this would not happen again. I had no adverse or ill effects from this in relation to my CMT or anything else. We need to be careful with vitamins and medications; it seems we are all aware of the lists. In addition, I keep in regular check with my doctor first regarding my general overall health and use of vitamins. My Los Angeles internist started me on 1000 I.U. of Vitamin E about 8 or 9 years ago and when I moved here, my internist learned something new - the theraputic affects of E for me - blood flow to muscles, plus the care of skeletal muscle tissue, so with my first internist's protocol, I continue to follow this. The article below is very old - from 1986, but about Vitamin E and CMT. I hope everyone keeps in contact with their internist on their vitamin and dietary needs. What I found disturbing about the Vitamin B article posted is that it did not mention CMT. Certainly, too much of anything is not recommended. So, I just urge everyone to talk to their doc about their specific dietary/vitamin needs. If we continue to share our personal experience in regards to CMT, we will continue to learn much. ~ Gretchen Abstract from Neurology. 1986 Sep;36(9):1200-5. Dietary essential fatty acids, vitamin E, and Charcot-Marie-Tooth disease. LL, O'Dougherty MM, FS, Bobulski RJ, Horrocks LA. Twenty patients with type I Charcot-Marie-Tooth disease received dietary supplementation with the essential fatty acids (EFA), linoleic and gamma-linolenic acids, and vitamin E. A 3-month blinded trial of placebo (paraffin oil and vitamin E, 81.6 IU/d) was followed by 1 year of 3 grams daily of EFA and vitamin E. Serum fatty acid values doubled, but total esterified fatty acid proportions did not change. Arachidonic acid proportions correlated with the amount of prostaglandin-mediated lymphocyte suppression measured at the same times. Improvement demonstrated at the end of the placebo period by neuropsychological tests and neurologic examination was maintained during the 1 year of EFA supplementation. This effect may reflect a membrane stabilization benefit of vitamin E. Quote Link to comment Share on other sites More sharing options...
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