RE: Rational Use of Antimicrobials- Attn Kaushik

[Guest guest]

Dear Kaushik and All, Sensitisation of Doctors, Pharmacists and nurses regarding Rational use of Antimicrobial is the need of the hour Intervention at the Regulatory authority level is very vital and key step to prevent antimicrobial resistane. That means we will have Rational combination of antibiotics in the market Quality of Antobiotics in different formulation will also improve specifically its Dose Trupti kaushik chakraborty <kaushik_chakr@...> wrote: Dear Friends, This is definitely a great subject and a need of the hour to discuss, formulate policies and above all strict gov supervision to withdraw all harmful irrational drugs from the market. Surely this is not going to be good news for the Indian and Multinational pharma companies operating in INDIA if all the physicians stop

prescribing irrational fixed dose cominations which are abandant due to absence of strict regulatory regulations in india unlike other developed nations like US. We need regular sensitisation interms of CMEs that keep reminding us - Usefulness of Rational drug prescribing. Good news is that at last, there has been some actions from drug general governor of India and they asked several companies ( including some reputed ones like ranbaxy, cipla etc) to withdraw many of their presently available irrational fixed drug combinations. Wishing all a brain storming session, Dr. Kaushik Chakraborty, RIMS.Trupti Swain <drtruptiswain > wrote: Dearv Kiran and Friends, I also feel that NetRUMians are not paying appropriate attention to a subject which needs thorough

discussion. Everybody, starting from physician, patient himself Pharma industry and policy makers contribute to this problem. But the treating physician should take maximum responsibility. Because he is in right position to decide either to prescribe or not prescribe antibiotics and he should also provide proper information, instruction and warning to the patient regarding regarding use of Antimicrobials Trupti kiranchaudhari7 (DOT) co.in wrote: dear friends,this one is really a topic of public health importance and the topic that has

been constantly or deliberately paid no attention or we can say ignored since long time in spite of the emergence of resistance for antimicrobials on large scale.(I am feeling that the NetRUMians are also paying no attention on this topic, the number of reply depicts it.)Nevertheless, who shall be blamed?The physician who treats?The patient who is non compliant?The manufacturers who device irrational combinations?The policy makers and implementars who never keep a vigilance on all these ongoing processes?Who?And next important aspect is regarding the steps that shall be followed to tackle or curb this problem on large scale.What shall be done?Any suggestions?Dr Kiran ChaudhariLecturer, Pharmacology,GMC, Nagpur.-- original message --Subject: Rational Use of Antimicrobials- Surgical ProphylaxisFrom: Trupti Swain <drtruptiswain >Date: 21st December 2007 11:18:30 Friends, With relation to my previous posting, I want to point out thatAntimicrobial Prophylaxis is highly recommended in - Gastro-intestinal and colorectal surgery, - Contaminated and dirty wound surgery - During prosthesis implantation. - Biliary or genito-urinal surgeries, - Cardiac, thoracic and breast surgeries-Clean contaminated surgery - Surgery in the old aged above 60 years. But not recommended in- clean head and neck surgery,- nose and sinus surgery - Clean uncontaminated surgeries, however, this view remains controversial.As the most common organism causing surgical site infection include staph aureus,coagulase negative staph, enterococcus and e.coli, the first generation cephalosporins are the drugs of first choice for most clean procedures due to their safety,

long half life and low cost. Metronidazole is indicated in all abdominal surgeries. Vancomycin or linezolid are indicated for methicillin resistant staph aureus associated with most nosocomial infections and prosthesis or vascular graft surgeries. Other antibiotics usually used include penicillin G and other beta-lactams for streptococcal and pnemococcal infections, 2nd gen cephalosporins for e.coli, proteus, klebseilla or mixed infections, 3rd generation cephalosporins for enterobacteriaceae, and the higher antibiotics like clindamycin, imipenem, meropenem for the most commonly encountered anaerobe B. fragilis Trupti---------------------------------Never miss a thing. Make your homepage.Send instant messages to your online friends http://in.messenger. Never miss a thing. Make your homepage. Meet people who discuss and share your passions. Join them now.

Be a better friend, newshound, and know-it-all with Mobile. Try it now.