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CMT disease carriers

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I found this on the CMT Australia website ~ G

Autosomal Recessive CMT Type 4A

Usually both parents of an affected child are clinically normal " disease

carriers " . This type of CMT is more common in countries where the

incidence of marring close relatives is higher. The parents have a 25%

recurrence risk to have an affected child.

The gene for one of these forms, CMT4A is located on chromosome 8 and it

is probable that two other genes can cause Types 4B and 4C although the

location of these types is not known. The genetic defect in CMT4A is not

yet known.

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