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TH imbalance can mimic psychiatric disease because T3 influences levels of serotonin, a neurotransmitter integral to moods and behavior. Low levels of T3 can cause depression. Some anti-depressants make hypothyroid patients feel even worse because the medications depress T3 levels. Paradoxically, some substances labelled depressants such as alcohol or opiates can increase T3 levels by impairing the breakdown of T3 in the brain, thus lifting mood. This may be one reason why these substances are so addictive

I thought this was interesting after the recent disscussion on anti depressants, and doctors still insist we need the AD's!!

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