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Abrahams on bromide clearance with salt

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Here's a bit more from AbrahamsLynnhttp://www.townsendletter.com/Oct2005/gabyrebuttal1005.htmTo be discussed later, in cases of increased mobilization of bromide

from storage sites by orthoiodosupplementation and elevated serum

bromide levels high enough to cause bromism, the administration

of sodium chloride

(6-10 gm/day) increases the renal clearance of bromide by

10 fold and minimizes the side effects of bromism. If orthoiodosupplementation

results in elevated urine lead levels, together with increased

bromide,

ammonium chloride is preferable to sodium chloride since it is

the chloride that increases renal clearance of bromide. The ammonium

is

metabolized to urea and has an acidifying effect, which increases

renal clearance of lead also.

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