Re: Vitiligo treatment; still more ideas.

[Guest guest]

Vitiligo is the loss of melanin, the pigment in the skin. Below are causes and treatments I found in Dr. Jonathon 's newsletter (Nutrition and Healing) and also from a website explaining what is needed for melanin to be made. Note: since low stomach acid makes it difficult for the body to absorb vitamin  B12 and folic acid (both of which are necessary for melanin production), the factors below are interrelated with each other and also with vitamin C, the need for which is increased by iodine consumption. Zinc and copper are also required both for melanin production and thyroid balance. Increased magnesium consumption may increase the need for zinc and thus for copper as well. Body odor, a symptom of iodine induced boron dumping, can also be related to zinc deficiency. Also, tyrosine is used to make thyroid, so iodine supplementation may divert scarce tyrosine to thyroid production and cause a deficiency for melanin production. Much to think about in terms of maximizing nutrition while we supplement with iodine to avoid possible negative side effects like vitiligo. A friend has successfully controlled her vitiligo with Selsun Blue (dandruff shampoo!) for years!Hope this helps,AdehaLow Stomach Acid: "To save space, I’ll just make a list of some of the numerous conditions linked to (and made worse by) low stomach acid: Acne rosacea, aging (especially 60 and older), allergies, alcoholism, celiac disease, childhood asthma, hepatitis, hives, depression, dermatomyositis, diabetes (Type 1), eczema, gallbladder disease, Graves’ disease, lupus, macular degeneration, multiple sclerosis, myasthenia gravis, osteoporosis, pernicious anemia, polymyalgia rheumatica, Raynaud’s syndrome, rheumatoid arthritis, scleroderma, Sjogren’s syndrome, ulcerative colitis, and vitiligo." (Dr. Jonathon 's newsletter)Boron deficiency: Safe and inexpensive boron offers prostate cancer prevention and protection from autoimmune diseases. Although it's too early to say for certain, recent research findings indicate that the trace element boron may prevent prostate cancer and autoimmune diseases (which include lupus, Graves' disease, Hashimoto's disease, myasthenia gravis, scleroderma, type 1 diabetes, vitiligo, and multiple sclerosis). Since boron is most frequently found in vegetables and fruits (it's an essential mineral for plant life), and since it's safe and quite inexpensive as a supplement in low doses, it may be advisable to take immediate advantage of this relatively new information. (Dr. Jonathon 's newsletter)How Melanin is Madehttp://www.recouleur.com/pigment.aspThe body's pigment production process, melanin synthesis, is like a factory. Various vitamins, minerals, and enzymes are needed during different phases on the "assembly line". If an ingredient is missing or the body cannot make it, then the finished product, pigment, cannot be made. Melanin is the pigment in the body that colors skin and hair. It is produced in cells called melanocytes. Melanocytes are located in the top skin layer.The amino acid phenylalanine is converted to the amino acid tyrosine. Melanin is formed by the conversion of the amino acid tyrosine. Tyrosine, in the presence of the enzyme tyrosinase and oxygen, is oxidized to dopa which is oxidized to dopaquinone. Then dopaquinone spontaneously changes to leukodopachrome. Leukodopachrome is easily oxidized to dopachrome. Carboxyl, an acid, is removed from dopachrome and dopachrome is rearranged resulting in melanin. Vitamins and minerals are used along the way. Among them is folic acid. Folic acid has three components: Pteridine; Para-aminobenzoic acid (PABA); L-glutamic acid. Phenylalanine needs pteridine to introduce hydrogen and oxygen which are required for the conversion to tyrosine to take place.PABA is needed for melanin creation as it helps metabolize B vitamins. Pantothenic acid, folic acid and B12 are the B vitamins used in melanin synthesis. In addition, about 21% of vitiligo patients are deficient in folic acid. Vitamin C is needed for folic acid metabolism. Folic acid and vitamin B12 require each other for biologic reactions. And, vitamin B12 plays a role in tyrosine metabolism. Thus folic acid in its whole is more effective than the sum of its parts. Tyrosinase requires copper for the oxidation of tyrosine to dopa. Tyrosinase contains two atoms of copper per molecule. Furthermore, copper must be transported into the melanocytes and the melanosomes (organelles within melanocytes which store melanin) for their function. Copper requires the presence of pantothenic acid in order to be absorbed. PABA helps in the utilization of pantothenic acid melanin. Vitamin C enhances the rate of transformation of tyrosine to dopa.Clinical research shows that many vitiligo patients have abnormally low levels of folic acid, vitamin B12, and C. Other research reveals that copper and zinc are reduced in vitiliginous skin.Melanosomes are transferred to surrounding keratinocytes (skin cells) and within the hair shaft to pigment skin and hair.Vitiliginous skin often has melanocytes but they have lost their ability to produce melanin. The borders of the patches repigment first because the source of melanin comes from melanocytes near the patch. Sunlight or equivalent artificial light helps transfer the melanin. A melanin reservoir exists in hair follicles. When melanin production is stimulated, it helps the migration of melanin to the hair.

[Guest guest]

thanks for the info sandra Adeha Feustel <adeha@...> wrote: Vitiligo is the loss of melanin, the pigment in the skin. Below are causes and treatments I found in Dr. Jonathon 's newsletter (Nutrition and Healing) and also from a website explaining what is needed for melanin to be made. Note: since low stomach acid makes it difficult for the body to absorb vitamin B12 and folic acid (both of which are necessary for melanin production), the factors below are interrelated with each other and also with vitamin C, the need for which is increased by iodine consumption. Zinc and copper are also required both for melanin production and thyroid balance. Increased magnesium consumption may increase the need for zinc and thus for copper as well. Body odor, a symptom of iodine induced boron dumping, can also be related to zinc deficiency. Also, tyrosine is used to make thyroid, so iodine supplementation may divert scarce tyrosine to thyroid production and cause a deficiency for melanin production. Much to think about in terms of maximizing nutrition while we supplement with iodine to avoid possible negative side effects like vitiligo. A friend has successfully controlled her vitiligo with

Selsun Blue (dandruff shampoo!) for years! Hope this helps, Adeha Low Stomach Acid: "To save space, I’ll just make a list of some of the numerous conditions linked to (and made worse by) low stomach acid: Acne rosacea, aging

(especially 60 and older), allergies, alcoholism, celiac disease, childhood asthma, hepatitis, hives, depression, dermatomyositis, diabetes (Type 1), eczema, gallbladder disease, Graves’ disease, lupus, macular degeneration, multiple sclerosis, myasthenia gravis, osteoporosis, pernicious anemia, polymyalgia rheumatica, Raynaud’s syndrome, rheumatoid arthritis, scleroderma, Sjogren’s syndrome, ulcerative colitis, and vitiligo." (Dr. Jonathon 's newsletter) Boron deficiency: Safe and inexpensive boron offers prostate cancer prevention and protection from autoimmune diseases. Although it's too early to say for certain, recent research findings indicate that the trace element boron may prevent prostate cancer and autoimmune diseases (which include lupus, Graves' disease, Hashimoto's disease, myasthenia gravis, scleroderma, type 1 diabetes, vitiligo, and multiple sclerosis). Since boron is most frequently found in vegetables and fruits (it's an essential mineral for plant life), and since it's safe and quite

inexpensive as a supplement in low doses, it may be advisable to take immediate advantage of this relatively new information. (Dr. Jonathon 's newsletter) How Melanin is Made http://www.recouleur.com/pigment.asp The body's pigment production process, melanin synthesis, is like a factory. Various vitamins, minerals, and enzymes are needed during different phases on the "assembly line". If an ingredient is

missing or the body cannot make it, then the finished product, pigment, cannot be made. Melanin is the pigment in the body that colors skin and hair. It is produced in cells called melanocytes. Melanocytes are located in the top skin layer. The amino acid phenylalanine is converted to the amino acid tyrosine. Melanin is formed by the conversion of the amino acid tyrosine. Tyrosine, in the presence of the enzyme tyrosinase and oxygen, is oxidized to dopa which is oxidized to dopaquinone. Then dopaquinone spontaneously changes to leukodopachrome. Leukodopachrome is easily oxidized to dopachrome. Carboxyl, an acid, is removed from dopachrome and dopachrome is rearranged resulting in melanin. Vitamins and minerals are used along the way. Among them is folic acid. Folic acid has three components: Pteridine; Para-aminobenzoic acid (PABA); L-glutamic

acid. Phenylalanine needs pteridine to introduce hydrogen and oxygen which are required for the conversion to tyrosine to take place. PABA is needed for melanin creation as it helps metabolize B vitamins. Pantothenic acid, folic acid and B12 are the B vitamins used in melanin synthesis. In addition, about 21% of vitiligo patients are deficient in folic acid. Vitamin C is needed for folic acid metabolism. Folic acid and vitamin B12 require each other for biologic reactions. And, vitamin B12 plays a role in tyrosine metabolism. Thus folic acid in its whole is more effective than the sum of its parts. Tyrosinase requires copper for the oxidation of tyrosine to dopa. Tyrosinase contains two atoms of copper per molecule. Furthermore, copper must be transported into the melanocytes and the melanosomes (organelles within melanocytes which store

melanin) for their function. Copper requires the presence of pantothenic acid in order to be absorbed. PABA helps in the utilization of pantothenic acid melanin. Vitamin C enhances the rate of transformation of tyrosine to dopa. Clinical research shows that many vitiligo patients have abnormally low levels of folic acid, vitamin B12, and C. Other research reveals that copper and zinc are reduced in vitiliginous skin. Melanosomes are transferred to surrounding keratinocytes (skin cells) and within the hair shaft to pigment skin and hair.Vitiliginous skin often has melanocytes but they have lost their ability to produce melanin. The borders of the patches repigment first because the source of melanin comes from melanocytes near the patch. Sunlight or equivalent artificial light helps transfer the melanin. A melanin reservoir exists in hair follicles. When melanin production is stimulated, it helps the migration of melanin to the hair.

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[Guest guest]

>

Thanks for this info. I'm going to print it off and get my head

around it. It does appear that my iodine intake could be a possible

reason for my vitiligo. This was my worry, taking large amounts of

one thing causing imbalance in the body.

> Vitiligo is the loss of melanin, the pigment in the skin. Below

are

> causes and treatments I found in Dr. Jonathon 's newsletter

> (Nutrition and Healing) and also from a website explaining what is

> needed for melanin to be made. Note: since low stomach acid makes

it

> difficult for the body to absorb vitamin B12 and folic acid (both

of

> which are necessary for melanin production), the factors below are

> interrelated with each other and also with vitamin C, the need for

> which is increased by iodine consumption. Zinc and copper are also

> required both for melanin production and thyroid balance.

Increased

> magnesium consumption may increase the need for zinc and thus for

> copper as well. Body odor, a symptom of iodine induced boron

dumping,

> can also be related to zinc deficiency. Also, tyrosine is used to

> make thyroid, so iodine supplementation may divert scarce tyrosine

to

> thyroid production and cause a deficiency for melanin production.

> Much to think about in terms of maximizing nutrition while we

> supplement with iodine to avoid possible negative side effects

like

> vitiligo. A friend has successfully controlled her vitiligo with

> Selsun Blue (dandruff shampoo!) for years!

> Hope this helps,

>

> Adeha

>

> Low Stomach Acid: " To save space, I'll just make a list of some of

> the numerous conditions linked to (and made worse by) low stomach

> acid: Acne rosacea, aging (especially 60 and older), allergies,

> alcoholism, celiac disease, childhood asthma, hepatitis, hives,

> depression, dermatomyositis, diabetes (Type 1), eczema,

gallbladder

> disease, Graves' disease, lupus, macular degeneration, multiple

> sclerosis, myasthenia gravis, osteoporosis, pernicious anemia,

> polymyalgia rheumatica, Raynaud's syndrome, rheumatoid arthritis,

> scleroderma, Sjogren's syndrome, ulcerative colitis, and

> vitiligo. " (Dr. Jonathon 's newsletter)

>

> Boron deficiency: Safe and inexpensive boron offers prostate

cancer

> prevention and protection from autoimmune diseases. Although it's

too

> early to say for certain, recent research findings indicate that

the

> trace element boron may prevent prostate cancer and autoimmune

> diseases (which include lupus, Graves' disease, Hashimoto's

disease,

> myasthenia gravis, scleroderma, type 1 diabetes, vitiligo, and

> multiple sclerosis). Since boron is most frequently found in

> vegetables and fruits (it's an essential mineral for plant life),

and

> since it's safe and quite inexpensive as a supplement in low

doses,

> it may be advisable to take immediate advantage of this relatively

> new information. (Dr. Jonathon 's newsletter)

>

>

>

> How Melanin is Made

>

> http://www.recouleur.com/pigment.asp

>

> The body's pigment production process, melanin synthesis, is like

a

> factory. Various vitamins, minerals, and enzymes are needed during

> different phases on the " assembly line " . If an ingredient is

missing

> or the body cannot make it, then the finished product, pigment,

> cannot be made. Melanin is the pigment in the body that colors

skin

> and hair. It is produced in cells called melanocytes. Melanocytes

are

> located in the top skin layer.

>

> The amino acid phenylalanine is converted to the amino acid

tyrosine.

> Melanin is formed by the conversion of the amino acid tyrosine.

> Tyrosine, in the presence of the enzyme tyrosinase and oxygen, is

> oxidized to dopa which is oxidized to dopaquinone. Then

dopaquinone

> spontaneously changes to leukodopachrome. Leukodopachrome is

easily

> oxidized to dopachrome. Carboxyl, an acid, is removed from

dopachrome

> and dopachrome is rearranged resulting in melanin. Vitamins and

> minerals are used along the way. Among them is folic acid. Folic

acid

> has three components: Pteridine; Para-aminobenzoic acid (PABA); L-

> glutamic acid. Phenylalanine needs pteridine to introduce hydrogen

> and oxygen which are required for the conversion to tyrosine to

take

> place.

>

> PABA is needed for melanin creation as it helps metabolize B

> vitamins. Pantothenic acid, folic acid and B12 are the B vitamins

> used in melanin synthesis. In addition, about 21% of vitiligo

> patients are deficient in folic acid. Vitamin C is needed for

folic

> acid metabolism. Folic acid and vitamin B12 require each other for

> biologic reactions. And, vitamin B12 plays a role in tyrosine

> metabolism. Thus folic acid in its whole is more effective than

the

> sum of its parts. Tyrosinase requires copper for the oxidation of

> tyrosine to dopa. Tyrosinase contains two atoms of copper per

> molecule. Furthermore, copper must be transported into the

> melanocytes and the melanosomes (organelles within melanocytes

which

> store melanin) for their function. Copper requires the presence of

> pantothenic acid in order to be absorbed. PABA helps in the

> utilization of pantothenic acid melanin. Vitamin C enhances the

rate

> of transformation of tyrosine to dopa.

>

> Clinical research shows that many vitiligo patients have

abnormally

> low levels of folic acid, vitamin B12, and C. Other research

reveals

> that copper and zinc are reduced in vitiliginous skin.

>

> Melanosomes are transferred to surrounding keratinocytes (skin

cells)

> and within the hair shaft to pigment skin and hair.

>

> Vitiliginous skin often has melanocytes but they have lost their

> ability to produce melanin. The borders of the patches repigment

> first because the source of melanin comes from melanocytes near

the

> patch. Sunlight or equivalent artificial light helps transfer the

> melanin. A melanin reservoir exists in hair follicles. When

melanin

> production is stimulated, it helps the migration of melanin to the

hair.

>

[Guest guest]

>

Adeha,

May i re post this info on the thyroid forum. We were discussing

vitiligo there awhile ago. I will put your name to it.

>

[Guest guest]

I found that I would get some new symptoms that would last 6 weeks and then go away. Maybe this is transitory? Iodine is very important to skin health.

Gracia

>Thanks for this info. I'm going to print it off and get my head around it. It does appear that my iodine intake could be a possible reason for my vitiligo. This was my worry, taking large amounts of one thing causing imbalance in the body.

..

[Guest guest]

> >

>

> Thanks for this info. I'm going to print it off and get my head

> around it. It does appear that my iodine intake could be a

possible

> reason for my vitiligo. This was my worry, taking large amounts

of

> one thing causing imbalance in the body.

>

>

>

>

> Recent Activity

> a.. 14New Members

> Visit Your Group

>

[Guest guest]

sarah & gracia, just for info, my m-i-l always said these spots were a calcium deficiency. Is there a test for high tissue calcium sandraslyan2007 <slyan2007@...> wrote: > >> > Thanks for this info. I'm going to print it off and get my head > around it. It does appear that my iodine intake could be a possible > reason for my vitiligo. This was my worry, taking large amounts of > one thing causing imbalance in the body.> > > > > Recent Activity> a.. 14New Members> Visit Your Group >

[Guest guest]

> > >

> >

> > Thanks for this info. I'm going to print it off and get my head

> > around it. It does appear that my iodine intake could be a

> possible

> > reason for my vitiligo. This was my worry, taking large amounts

> of

> > one thing causing imbalance in the body.

> >

> >

> >

> >

> > Recent Activity

> > a.. 14New Members

> > Visit Your Group

> >

[Guest guest]

Why would calcium deficiency give high tissue calcium .

I too have these white spots(posted b4), and although my blood

levels of calcium are normal now, they used to be a little on the low

side(though still in normal range0.. my PTH has risen and its take

some calcium form my teeth , and probably other bones.. so my blood

calciumm is normal (calcium homeostatis).. but I've no idea of tissue

calcium.

It was low in a hair analysis.. 20 yrs ago too. My hair analysis

always confirms my blood tests too.. always about same place in

range. in hair analysis , calcium was below normal.(

I've just sent off for another hair analysis..but as I had to use

pubic hair(hair dyed, and not much left anyway!) it may not be that

accurate for calcium.?

I've started taken more calcium supplements, i always took some...

but i'm wondering how this fits in with white spots. I only got the

white spots after going on Armour and t4 thyroid meds..

I was also beginning to think it was somehow related to iodine ..

Jan

>

> sarah & gracia,

> just for info, my m-i-l always said these spots were a calcium

deficiency. Is there a test for high tissue calcium

> sandra

>

>

[Guest guest]

I had vitiligo type spots before I ever took iodine. I thought it was

caused by the hypothyroidism. I had white patches (only on my face)

that wouldn't tan for about 3 years before I was ever diagnosed with a

thyroid problem. I had asked Drs. about the screwy tan but they

dismissed it.

[Guest guest]

>

That's what i don't get, if it is hypo related, why get it after

going on Armour. Why did i not have it before. I got mine 4 months

after starting Armour and iodine. As I started Armour and iodine

around the same time, it is difficult to know which one, if any, is

causing the problem.

.. I only got the

> white spots after going on Armour and t4 thyroid meds..

> I was also beginning to think it was somehow related to iodine ..

> Jan

>

>

>

[Guest guest]

really? that is interesting. Is vitiligo the same as hyper/hypopigmentation? which is a low adrenal symptom.

I am taking cal/mag 1:1 ratio and 2000iu vitamin D.

Gracia

sarah & gracia,

just for info, my m-i-l always said these spots were a calcium deficiency. Is there a test for high tissue calcium

sandraslyan2007 <slyan2007 (DOT) co.uk> wrote:

---

..

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[Guest guest]

that is fascinating to me that you feel no different on or off Iodoral. I wonder if that means you are resistant and should try higher dose?

Gracia.

>> Hi Gracia,I thought that also, it could be transitory. I remember you saying that you would get stuff happening that then went away. I really don't know what to do now. I have been off iodine for a couple of weeks, well except for the odd day i took it. I'm sure i need it as i also have lymphomas. Although it doesn't make me feel any different now, whether i'm on it or not, unlike my hubbie that notices the increase in energy. Maybe for an experimental exercise i should carry on to see if they eventually go. I'm really scared the spots will reach my face though. It is interesting a lot of hashi's folk get vitiligo, and Edgar Cayce says take iodine for it, albeit detoxified iodine, why detoxified i still don't know. Another thing that crossed my mind is that i have high tissue calcium, could these spots be something to do with that, the iodine cleansing the cells, maybe. Well i suppose i won't know unless i carry on with the iodine and see what happens.

..

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