Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 Maybe it's controversial to some folks, but for those of us using iodine for cancer, we have the proof in our own bodies. Even the UN is saying that iodine deficiency is a problem--even in children in Europe for pete's sake. ----- Original Message ----- > Hi all...I received a long list of studies indicating that supplemental > iodine can be harmful. The studies were collected by Dr. Ray Peat...I > am not knowledgeable enough to determine whether these studies can be > distinguished and explained away from the work performed by Dr. > Abraham. I am happy to email these studies to anyone who might be able > to comment or others who share my concern that iodine might be harmful > in high doses. For the record, I am taking 12.5 mgs a day of Iodoral > with ATP co-factors...I have been feeling extremely sleepy and > wondering whether the iodine might be harming me in some way....any > input appreciated. I hope that we enjoy free speech on this board and > that my post will not get blocked. I am just trying to get my arms > around this controversial subject. God bless all! > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 I enjoy reading Peat's work. He doesn't have any articles listing iodine as harmful on his website. How do you know the articles were collected by Peat? Linn > > Hi all...I received a long list of studies indicating that supplemental > iodine can be harmful. The studies were collected by Dr. Ray Peat...I > am not knowledgeable enough to determine whether these studies can be > distinguished and explained away from the work performed by Dr. > Abraham. I am happy to email these studies to anyone who might be able > to comment or others who share my concern that iodine might be harmful > in high doses. For the record, I am taking 12.5 mgs a day of Iodoral > with ATP co-factors...I have been feeling extremely sleepy and > wondering whether the iodine might be harming me in some way....any > input appreciated. I hope that we enjoy free speech on this board and > that my post will not get blocked. I am just trying to get my arms > around this controversial subject. God bless all! > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 hey, iodine family! i did some googling and didn't find anything in the articles i found! "CC", can we have web links to check these out??? thanks in advance! sincerely, sandimwm1glm <mwm1glm@...> wrote: I enjoy reading Peat's work. He doesn't have any articles listing iodine as harmful on his website. How do you know the articles were collected by Peat?Linn>> Hi all...I received a long list of studies indicating that supplemental > iodine can be harmful. The studies were collected by Dr. Ray Peat...I > am not knowledgeable enough to determine whether these studies can be > distinguished and explained away from the work performed by Dr. > Abraham. I am happy to email these studies to anyone who might be able > to comment or others who share my concern that iodine might be harmful > in high doses. For the record, I am taking 12.5 mgs a day of Iodoral > with ATP co-factors...I have been feeling extremely sleepy and > wondering whether the iodine might be harming me in some way....any > input appreciated. I hope that we enjoy free speech on this board and > that my post will not get blocked. I am just trying to get my arms > around this controversial subject. God bless all!> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 Can I see some links on Ray Peats comments / research on Iodine? I can't find a thing of value when I google his name and Iodine. He is not well thought of in WAP " land " http://www.westonaprice.org/knowyourfats/essentialfattyaciddef.html Studies showing Iodine is harmful.... > Hi all...I received a long list of studies indicating that supplemental > iodine can be harmful. The studies were collected by Dr. Ray Peat...I > am not knowledgeable enough to determine whether these studies can be > distinguished and explained away from the work performed by Dr. > Abraham. I am happy to email these studies to anyone who might be able > to comment or others who share my concern that iodine might be harmful > in high doses. For the record, I am taking 12.5 mgs a day of Iodoral > with ATP co-factors...I have been feeling extremely sleepy and > wondering whether the iodine might be harming me in some way....any > input appreciated. I hope that we enjoy free speech on this board and > that my post will not get blocked. I am just trying to get my arms > around this controversial subject. God bless all! > > > ------------------------------------ > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 Do a Google on " Ray Peat on Iodine " and you'll find lots > > Can I see some links on Ray Peats comments / research on Iodine? I can't > find a thing of value when I google his name and Iodine. > > He is not well thought of in WAP " land " > http://www.westonaprice.org/knowyourfats/essentialfattyaciddef.html > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 Peat talks about radioactive iodine in the articles I've read, Is that what you are referencing? Linn > > > > Can I see some links on Ray Peats comments / research on Iodine? I > can't > > find a thing of value when I google his name and Iodine. > > > > He is not well thought of in WAP " land " > > http://www.westonaprice.org/knowyourfats/essentialfattyaciddef.html > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 Thanks very much for posting that, . I really respect Enig. This pretty much discredits him in my eyes. Ann Marie On Apr 29, 2008, at 7:12 PM, ladybugsandbees wrote: > Can I see some links on Ray Peats comments / research on Iodine? I > can't > find a thing of value when I google his name and Iodine. > > He is not well thought of in WAP " land " > http://www.westonaprice.org/knowyourfats/essentialfattyaciddef.html Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 I read this article a while back. Peat's info on hormones is highly regarded. He's like everybody else, not perfect!! Linn > > Can I see some links on Ray Peats comments / research on Iodine? I can't > find a thing of value when I google his name and Iodine. > > He is not well thought of in WAP " land " > http://www.westonaprice.org/knowyourfats/essentialfattyaciddef.html > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 Hey Sandi...I got the articles from another source...I am happy to email them to you if you contact me offline....If you can distinguish them in some way from Abraham and Brownstien's (A & work...I would appreciate it. Peat is adamantly opposed to the use of iodine...and that troubles me because I respect his work. He says its best to completely ignore everything that A & B are reporting. I recently read B's book and Dr. Derry's book on iodine and found them to be persuasive...I started taking iodorol but backed off when I got so sleepy I couldn't make it through the day. Would appreciate any input you have on the sleepiness or other relevant info. > > > > Hi all...I received a long list of studies indicating that supplemental > > iodine can be harmful. The studies were collected by Dr. Ray Peat...I > > am not knowledgeable enough to determine whether these studies can be > > distinguished and explained away from the work performed by Dr. > > Abraham. I am happy to email these studies to anyone who might be able > > to comment or others who share my concern that iodine might be harmful > > in high doses. For the record, I am taking 12.5 mgs a day of Iodoral > > with ATP co-factors...I have been feeling extremely sleepy and > > wondering whether the iodine might be harming me in some way....any > > input appreciated. I hope that we enjoy free speech on this board and > > that my post will not get blocked. I am just trying to get my arms > > around this controversial subject. God bless all! > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 Sure...lady...email me and I will forward them to you. I didn't know that the " Price " folks are not enamored with Peat. > > Can I see some links on Ray Peats comments / research on Iodine? I can't > find a thing of value when I google his name and Iodine. > > He is not well thought of in WAP " land " > http://www.westonaprice.org/knowyourfats/essentialfattyaciddef.html > > > > > > Studies showing Iodine is harmful.... > > > > Hi all...I received a long list of studies indicating that supplemental > > iodine can be harmful. The studies were collected by Dr. Ray Peat...I > > am not knowledgeable enough to determine whether these studies can be > > distinguished and explained away from the work performed by Dr. > > Abraham. I am happy to email these studies to anyone who might be able > > to comment or others who share my concern that iodine might be harmful > > in high doses. For the record, I am taking 12.5 mgs a day of Iodoral > > with ATP co-factors...I have been feeling extremely sleepy and > > wondering whether the iodine might be harming me in some way....any > > input appreciated. I hope that we enjoy free speech on this board and > > that my post will not get blocked. I am just trying to get my arms > > around this controversial subject. God bless all! > > > > > > ------------------------------------ > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 That's ridiculous. How can you ignore what iodine is actually doing for people? I would ignore someone who told me iodine is harmful. ----- Original Message ----- . He > says its best to completely ignore everything that A & B are > reporting. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 Me too . When it is an all or nothing that is where I lose it. I have more tolerance for those that state in certain conditions it is applicable. Steph Re: Re: Studies showing Iodine is harmful.... > That's ridiculous. How can you ignore what iodine is actually doing for > people? I would ignore someone who told me iodine is harmful. > > > > ----- Original Message ----- . > > He >> says its best to completely ignore everything that A & B are >> reporting. > > > ------------------------------------ > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 I too am less inclined to ignore what is working quite well for me. Much of A & B's info is logical and i am finding it helpful. Isn't Peat an endo? I personally have not had great care from endo's . Just putting my two cents in here. I certainly am open to others' ideas, but it is hard to ignore the progress from so many here that have been helped by A and B's research. My thought to the person who started this thread. You will likely never find info that definitively proves one way or the other what is the right way for you to do....my question to you...do you want to sit in doubt or do you want to take the chance that this may work for you?. I too could have ignored Brownstein as i am a Hashi's Hypo and allegedly iodine isn't tolerated well by them . I have been on 50 mgs for one month, have had very minor side effects/detox... and find it enormously helpful. Take the plunge!DeCubellis Ranch <decubellisranch@...> wrote: That's ridiculous. How can you ignore what iodine is actually doing for people? I would ignore someone who told me iodine is harmful.----- Original Message ----- .He> says its best to completely ignore everything that A & B are> reporting. ------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 Peat is a biochemist. Linn > > I too am less inclined to ignore what is working quite well for me. Much of A & B's info is logical and i am finding it helpful. Isn't Peat an endo? I personally have not had great care from endo's . > Just putting my two cents in here. I certainly am open to others' ideas, but it is hard to ignore the progress from so many here that have been helped by A and B's research. > My thought to the person who started this thread. You will likely never find info that definitively proves one way or the other what is the right way for you to do....my question to you...do you want to sit in doubt or do you want to take the chance that this may work for you?. I too could have ignored Brownstein as i am a Hashi's Hypo and allegedly iodine isn't tolerated well by them . I have been on 50 mgs for one month, have had very minor side effects/detox... and find it enormously helpful. Take the plunge! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 I know Peat is adamantly against the use of radioactive iodine. I still haven't been able to find anything written by Peat contradicting the iodine docs. Why can't you post the articles here? Linn > > Hey Sandi...I got the articles from another source...I am happy to > email them to you if you contact me offline....If you can > distinguish them in some way from Abraham and Brownstien's (A & > work...I would appreciate it. Peat is adamantly opposed to the use > of iodine...and that troubles me because I respect his work. He > says its best to completely ignore everything that A & B are > reporting. I recently read B's book and Dr. Derry's book on iodine > and found them to be persuasive...I started taking iodorol but > backed off when I got so sleepy I couldn't make it through the day. > Would appreciate any input you have on the sleepiness or other > relevant info. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 I'd love to see them too. Ann Marie On Apr 30, 2008, at 9:23 AM, CC wrote: > Sure...lady...email me and I will forward them to you. I didn't > know that the " Price " folks are not enamored with Peat. > > > --- In iodine , " ladybugsandbees " Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 http://thyroid.about.com/gi/dynamic/offsite.htm? site=http://www.thyroid%2Dinfo.com/articles/ray%2Dpeat.htm Shomon: Do you think the majority of people with hypothyroidism get too much or too little iodine? Should people with hypothyroidism add more iodine, like kelp, seaweeds, etc.? Dr. Ray Peat: 30 years ago, it was found that people in the US were getting about ten times more iodine than they needed. In the mountains of Mexico and in the Andes, and in a few other remote places, iodine deficiency still exists. Kelp and other sources of excess iodine can suppress the thyroid, so they definitely shouldn't be used to treat hypothyroidism. cindi > > I know Peat is adamantly against the use of radioactive iodine. > > I still haven't been able to find anything written by Peat contradicting the iodine docs. > > Why can't you post the articles here? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 I wonder how many patients he has helped/seen over the last 10 years to draw his conclusion. Duke ---------------------------------> Hope your day goes well. 214-823-7070 iodine From: mwm1glm@...Date: Wed, 30 Apr 2008 18:58:20 +0000Subject: Re: Studies showing Iodine is harmful.... Peat is a biochemist.LinnVisit Your Group | Terms of Use | Unsubscribe Recent Activity 18 New MembersVisit Your Group Meditation and Lovingkindness A Group to share and learn. Health Early Detection Know the symptoms of breast cancer. Sell Online Start selling with our award-winning e-commerce tools. .. Make i'm yours. Create a custom banner to support your cause. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 Thanks ...all replies to my query are appreciated...the authorities on both sides of this issue seem to be well qualified and both sides are adamant that they are right....its up to us guinea pigs to sort things out...I have received a lot of email offline indicating people's negative experience with iodine in response to my original post. Most of those who emailed me advised that they were afraid to post negative experiences on this board for fear of being shouted down...and thats a shame! All of us sick folks have a common bond and a common mission....to get better...anything less than a free and open discussion will hamper our ability to learn and get better. I hope everyone will feel free to post their experience positive or negative with iodine. > > That's ridiculous. How can you ignore what iodine is actually doing for > people? I would ignore someone who told me iodine is harmful. > > > > ----- Original Message ----- . > > He > > says its best to completely ignore everything that A & B are > > reporting. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 and more.... Endocrinol Metab Clin North Am 1987 Jun;16(2):327-42 Environmental factors affecting autoimmune thyroid disease. Safran M, TL, Roti E, Braverman LE. Department of Medicine, University of Massachusetts Medical Center, Worcester. A number of environmental factors affect the incidence and progression of autoimmune thyroid disease. Exposure to excess iodine, certain drugs, infectious agents and pollutants, and stress have all been implicated. Science 1985 Oct 18;230(4723):325-7 Induction of autoimmune thyroiditis in chickens by dietary iodine. Bagchi N, Brown TR, Urdanivia E, Sundick RS. Clinical studies have suggested that excess dietary iodine promotes autoimmune thyroiditis; however, the lack of a suitable animal model has hampered investigation of the phenomenon. In this study, different amounts of potassium iodide were added to the diets of chicken strains known to be genetically susceptible to autoimmune thyroiditis. Administration of iodine during the first 10 weeks of life increased the incidence of the disease, as determined by histology and the measurement of autoantibodies to triiodothyronine, thyroxine, and thyroglobulin. Further support for the relation between iodine and autoimmune thyroiditis was provided by an experiment in which iodine- deficient regimens decreased the incidence of thyroid autoantibodies in a highly susceptible strain. These results suggest that excessive consumption of iodine in the United States may be responsible for the increased incidence of autoimmune thyroiditis. Am J Clin Nutr. 2005 Apr;81(4):840-4. High thyroid volume in children with excess dietary iodine intakes. Zimmermann MB, Ito Y, Hess SY, Fujieda K, Molinari L. Human Nutrition Laboratory, Swiss Federal Institute of Technology, Zurich, Switzerland. michael.zimmermann@... BACKGROUND: There are few data on the adverse effects of chronic exposure to high iodine intakes, particularly in children. OBJECTIVE: The objective of thestudy was to ascertain whether high dietary intakes of iodine in children result in high thyroid volume (Tvol), a high risk of goiter, or both. DESIGN: In an international sample of 6-12-y-old children (n = 3319) from 5 continents with iodine intakes ranging from adequate to excessive, Tvol was measured by ultrasound, and the urinary iodine (UI) concentration was measured. Regressions were done on Tvol and goiter including age, body surface area, sex, and UI concentration as covariates. RESULTS: The median UI concentration ranged from 115 microg/L in central Switzerland to 728 microg/L in coastal Hokkaido, Japan. In the entire sample, 31% of children had UI concentrations >300 microg/L, and 11% had UI concentrations >500 microg/L; in coastal Hokkaido, 59% had UI concentrations >500 microg/L, and 39% had UI concentrations >1000 microg/L. In coastal Hokkaido, the mean age- and body surface area-adjusted Tvol was approximately 2-fold the mean Tvol from the other sites combined (P < 0.0001), and there was a positive correlation between log(UI concentration) and log(Tvol) (r = 0.24, P < 0.0001). In the combined sample, after adjustment for age, sex, and body surface area, log(Tvol) began to rise at a log(UI concentration) >2.7, which, when transformed back to the linear scale, corresponded to a UI concentration of approximately 500 microg/L. CONCLUSIONS: Chronic iodine intakes approximately twice those recommended-indicated by UI concentrations in the range of 300-500 microg/L-do not increase Tvol in children. However, UI concentrations >/=500 microg/L are associated with increasing Tvol, which reflects the adverse effects of chronic iodine excess. Multicenter Study Acta Endocrinol (Copenh) 1978 Aug;88(4):703-12 A case of Hashimoto's thyroiditis with thyroid immunological abnormality manifested after habitual ingestion of seaweed. Okamura K, Inoue K, Omae T. An interesting case of iodide induced goitre with immunological abnormalities is described. The patient who was sensitive to synthetic penicillin had previously been treated for exudative pleuritis, congestive heart failure and acute renal failure. Following recovery, he began to ingest large amounts of seaweed after which he developed goitrous hypothyroidism. It was of interest that the serum level of gamma-globulin increased, and subsequently the antithyroid microsomal antibody became strongly positive, suggesting that thyroidal autoimmune processes had been precipitated. Biopsy of the thyroid gland revealed chronic thyroiditis, with evidence suggesting extreme stimulation by TSH. Hight thyroidal uptake of 131I, positive perchlorate discharge test and biochemical analysis of the thyroidal soluble protein showed severe impairment of hormone synthesis following continuous accumulation of excess iodide. While there is evidence suggesting that increased iodide may be an important factor in the initiation of Hashimoto's thyroiditis, this may result from the marked increased sensitivity of Hashimoto's gland to the effects of iodine. Thus an occult lesion could be unmasked in this manner. The mechanism by which iodide mediates this effect is not clear. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 and more: Autoimmunity 1994;18(1):31-40 Iodide induced lymphocytic thyroiditis in the BB/W rat: evidence of direct toxic effects of iodide on thyroid subcellular structure. Li M, Boyages SC. Department of Clinical Endocrinology, Westmead Hospital, NSW, Australia. A high dietary iodine intake accelerates the development of lymphocytic thyroiditis (LT) in the BB/W rat. Our previous studies have defined the temporal sequence of the immunological events triggered by excess iodide intake in these animals. It was still not clear, however, whether these observed immunological changes were a direct effect on immune effector cells, or whether they represented a secondary response to a toxic effect of iodine on thyroid tissue. In the present study, the effect of excessive iodine intake on the subcellular structure of the BB/W rat thyroid gland, particularly, whether iodide had a toxic effect independent of its immune response has been examined. BB/W rats were exposed, prenatally through maternal drinking water, to excessive iodide at two doses (Moderate 3 x 10(-6) M iodide/l; High 3 x 10(-3) M iodide/l); a third group of BB/W rats was given tap water; till 12 weeks postnatal age. Two groups of Wistar rats received high dose iodide water or tap water for the same periodof time and served as controls. Thyroid gland ultrastructure was determined by electron microscopic (EM) examination. Thyroid 125I uptake and perchlorate discharge tests were also performed in separate experiments. We found that thyroid glands of non-iodine supplemented Wistar rats were morphlogically normal under EM. There were no overt changes in the iodide treated Wistar rats. By contrast, iodide treated BB/W rats exhibited marked accumulation of secondary lysosomes and lipid droplets; markedly swollen and disrupted mitochondria and extreme dilatation of rough endoplasmic reticulum (RER). Clin Immunol Immunopathol 1993 Nov;69(2):189-98 An excess of dietary iodine accelerates the development of a thyroid- associated lymphoid tissue in autoimmune prone BB rats. Mooij P, de Wit HJ, Drexhage HA. Department of Immunology, Erasmus University, Rotterdam, The Netherlands. Previous studies have shown that dietary iodine enhances the severity and incidence of focal thyroiditis in autoimmune BB rats and OS chickens. However, which lymphoid cells are involved in the development of the iodine- induced focal thyroiditis and what the consequences are for the anticolloid antibody production have not been studied in detail. We therefore performed a study in which 3-week-old female BB rats were kept on either an enriched iodine diet (EID; iodine intake, 100 micrograms iodine/day) or a normal iodine diet (NID; iodine intake, 7 micrograms iodine/day) for a period of 18 weeks. The development of the focal thyroiditis was immunohistologically studied. Immunohistological data were compared to the thyroid hormone status and anti-colloid antibody production. Our data confirm that a high dietary iodine intake results in an accelerated development of the focal lymphoid cell infiltrates in the thyroid of the BB rat. After 12-18 weeks of an EID 50% of the BB rats developed these infiltrates. Our data additionally show that: (a) the process starts with increases in the number of infiltrating MHC class II-positive dendritic cells and a clustering of these cells with T cells, B cells, and some macrophages and ( the focal infiltrates are highly organized and consist of central B cell follicle-like structures surrounded by rims and areas of T cells. The architecture of the focal thyroiditis is hence very similar to mucosa-associated lymphoid tissue and secondary lymphoid organs (spleen and lymph node). Only minor signs of thyrocyte destruction were observed. We therefore consider the term " thyroiditis " as inappropriate and prefer the term " thyroid-associated lymphoid tissue. " Since the thyroiditis component was small, it is also not surprising that the BB rats on the EID remained euthyroid. The presence of the thyroid-associated lymphoid tissue in the BB rats was positively correlated to the presence of anti- colloid antibody in the serum of the BB rats. We speculate that the dietary iodine might have direct effects on cells of the immune system or on cells forming the microenvironment of lymphoid tissue (reticulum cells). A role for highly iodinated thyroglobulin in the accelerated development of thyroid- associated lymphoid tissue is also possible. Endocrinology 1987 Aug;121(2):481-5 Iodine-induced thyroiditis and hypothyroidism in the hemithyroidectomized BB/W rat. EM, Appel MC, Braverman LE. We have recently reported that iodine administration (0.05% iodine in drinkingwater) to weanling, diabetes mellitus- and lymphocytic thyroiditis (LT)-prone Biobreeding Worcester (BB/W) rats strikingly increases the incidence of LT without occurrence of iodine-induced hypothyroidism, which frequently results when excess iodine is administered to euthyroid patients with Hashimoto's thyroiditis. Since hypothyroidism did not occur in the iodine- treated BB/W rats, hemithyroidectomy was carried out in 30-day-old BB/W rats to increase thyroid mass and functional reserve. Iodine administration for 60 days markedly increased antithyroglobulin antibodies (0.40 +/- 0.08 vs. 0.15 +/- 0.06 OD; P less than 0.02), the incidence of LT (68% vs. 13%; P less than 0.001), and thyroid weight of the residual lobe (10.5 +/- 0.7 vs. 6.3 +/- 0.3 mg/100 g BW; P less than 0.001) and induced hypothyroidism (T4, 2.5 +/- 0.2 vs. 3.0 micrograms/dL; P less than 0.05; T3, 25.1 +/- 1.9 vs. 37.5 ng/dL; P less than 0.001; TSH, 252 +/- 49 vs. 61 +/- 14 microU/mL; P less than 0.02). Hypothyroidism in the iodine-treated rats occurred primarily in those with LT. Similar studies were carried out in the non-diabetes mellitus-, non- LT-prone, genetically equivalent BB/W rats (W-line), the parent strain Wistar- Furth rats, and Sprague-Dawley rats. Iodine administration did not induce LT or antithyroglobulin antibodies in these three strains and did not affect thyroid function in Wistar-Furth and Sprague-Dawley rats. However, in the W- line rats, iodine excess did induce thyroid enlargement in the residual lobe (8.4 +/- 0.2 vs. 6.4 +/- 0.2 mg/100 g BW; P less than 0.001), a decrease in serum T3 (71.5 +/- 2.9 vs. 86.0 +/- 2.5 ng/dL; P less than 0.001), and an increase in serum TSH (344 +/- 65 vs. 69 +/- 6.0 microU/mL; P less than 0.001). It is evident, therefore, that hemithyroidectomy in BB/W rats sufficiently reduces functioning thyroid tissue, resulting in iodine-induced LT and hypothyroidism, similar to iodine-induced hypothyroidism in euthyroid patients with Hashimoto's thyroiditis. It is unclear, however, why iodine administration also induced hypothyroidism in hemithyroidectomized, genetically similar, W-line rats in the absence of LT. This observation suggests that iodine-induced hypothyroidism in rats may be genetically determined. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 I don't have time to read the whole list but this one jumped out at me. I have read that the Wolffe-Chaikoff study was done on rats and never proven to be true in human beings. B God Bless America! One nation under God > Lille.jl-wemeau@... > WOLFF-CHAIKOFF'S EFFECT: The thyroid gland has a capacity to reduce > thyroid > hormone production in the presence of excess iodine by reducing the > organification of the iodine. This Wolff-Chaikoff effect is observed > after 48 > hours and protects the organism from excessive synthesis of the > thyroid > hormones. This effect is usually temporary and within a few days > thyroid hormone > synthesis returns to normal through the so-called 'escape' > phenomenon. However > in a few normal individuals and in some susceptible patients, the > escape does > not occur. THE CONTEXT OF OCCURRENCE: Iodine-induced hypothyroidism > is observed in fetuses, newborn, adults and in the elderly. It is > observed in individuals > without underlying overt thyroid disorder, and specially in patients > with > autoimmune thyroiditis or those previously treated for thyroid > diseases (Graves' > disease, subacute or pospartum thyroiditis, iatrogenic thyroid > dysfunction...). Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 The key to the Wolffe Chaikoff study is that it was a temporary event and after a period of time all things normalized with the increased iodine. Re: Re: Studies showing Iodine is harmful.... > I don't have time to read the whole list but this one jumped out at me. > I have read that the Wolffe-Chaikoff study was done on rats and never > proven > to be true in human beings. > B > God Bless America! > One nation under God >> Lille.jl-wemeau@... >> WOLFF-CHAIKOFF'S EFFECT: The thyroid gland has a capacity to reduce >> thyroid >> hormone production in the presence of excess iodine by reducing the >> organification of the iodine. This Wolff-Chaikoff effect is observed >> after 48 >> hours and protects the organism from excessive synthesis of the >> thyroid >> hormones. This effect is usually temporary and within a few days >> thyroid hormone >> synthesis returns to normal through the so-called 'escape' >> phenomenon. However >> in a few normal individuals and in some susceptible patients, the >> escape does >> not occur. THE CONTEXT OF OCCURRENCE: Iodine-induced hypothyroidism >> is observed in fetuses, newborn, adults and in the elderly. It is >> observed in individuals >> without underlying overt thyroid disorder, and specially in patients >> with >> autoimmune thyroiditis or those previously treated for thyroid >> diseases (Graves' >> disease, subacute or pospartum thyroiditis, iatrogenic thyroid >> dysfunction...). > > > ------------------------------------ > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 I've read numerous studies on both sides of the fence regarding iodine, in particular regarding Hashi's, as my daughter had a raging case of it. Her antibodies were termed " astronomically high " by her doctor. He had never seen TPO that high and I have never found anyone else whose numbers came close to hers. There are also links to Hashi's being caused by too little iodine, in particular when there's been exposure to fluoride, which is right up our alley. I still don't see any references to Peat and anything he's written regarding the iodine docs. If there is any info written by Peat regarding that, I would be interested. It makes me question the articles also when they're referenced to being collected by Peat. I don't mean to be rude, but how can you substantiate that? Linn > > > > That's ridiculous. How can you ignore what iodine is actually doing > for > > people? I would ignore someone who told me iodine is harmful. > > > > > > > > ----- Original Message ----- . > > > > He > > > says its best to completely ignore everything that A & B are > > > reporting. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2008 Report Share Posted April 30, 2008 Thanks for pointing that out Linn. I too am looking for evidence presented by Peat that this is an issue - not the articles that were posted here. We were discussing Peat and I have yet to see his analysis. Steph Re: Studies showing Iodine is harmful.... > I've read numerous studies on both sides of the fence regarding iodine, in > particular > regarding Hashi's, as my daughter had a raging case of it. Her antibodies > were termed > " astronomically high " by her doctor. He had never seen TPO that high and > I have never > found anyone else whose numbers came close to hers. There are also links > to Hashi's > being caused by too little iodine, in particular when there's been > exposure to fluoride, > which is right up our alley. > > I still don't see any references to Peat and anything he's written > regarding the iodine docs. > If there is any info written by Peat regarding that, I would be > interested. It makes me > question the articles also when they're referenced to being collected by > Peat. I don't mean > to be rude, but how can you substantiate that? > > Linn > > >> > >> > That's ridiculous. How can you ignore what iodine is actually doing >> for >> > people? I would ignore someone who told me iodine is harmful. >> > >> > >> > >> > ----- Original Message ----- . >> > >> > He >> > > says its best to completely ignore everything that A & B are >> > > reporting. >> > >> > > > > > ------------------------------------ > > > > > Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.