Re: Re: My consult with Dr. Brownstein/Jingles

[Guest guest]

>>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef?Just curious.ThanksJingles<<<

No we did not discuss that. We didn't discuss "why" on anything which is part of the problem with a short phone consult. But I suspect the reason why he is doing those is because those are the two specific hormones I am low in. He is also supplementing the other hormones specifically. Your adrenals make other hormones and I think he likes to specifically dose the issues. He himself takes DHEA for allergies. He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.

Buist

[Guest guest]

Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to

use and let the body make its own cortisol.

Irene

At 04:06 AM 3/22/2006, you wrote:

>>>>Did

you discuss why he prefers pregnenolone + DHEA over Cortef?

Just curious.

Thanks

Jingles<<<

No we did not discuss that. We

didn't discuss " why " on anything which is part of the problem

with a short phone consult. But I suspect the reason why he is

doing those is because those are the two specific hormones I am low

in. He is also supplementing the other hormones specifically.

Your adrenals make other hormones and I think he likes to specifically

dose the issues. He himself takes DHEA for allergies. He said

he had been on allergy meds and an inhaler since 5 years old and when he

started taking DHEA he didn't have to take meds anymore.

Buist

[Guest guest]

>>>>Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to use and let the body make its own cortisol. Irene<<<

Thanks for sharing that. I am just beginning to learn about adrenals!

Buist

[Guest guest]

There seems to be an assumption that both DHEA and pregnenolone supplementation will replace other hormones that might be missing -- but I caution you in thinking that if you take a precursor hormone it will simply cascade into all the others. In the adrenals and ovary, etc. the biosynthesis of the all the hormones does take place --BECAUSE the necessary enzymes are available to promote the transformation of one to another. But when you take a substance orally there is no guarantee that the supplement will meet up with the necessary enzymes to make such a transformation. It is also highly individual -- one woman might raise her levels of estrogen from dhea while another boosts her testosterone or progesterone. That  being said, pregnenolone supplementation has been shown to increase  levels of dhea and progesterone while DHEA has been shown to up the levels of testosterone, estradiol and progesterone -- although their effects appear  different between males and females.LizOn Mar 22, 2006, at 4:06 AM, ladybugsandbees wrote:>>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef?Just curious.ThanksJingles<<< No we did not discuss that.  We didn't discuss "why" on anything which is part of the problem with a short phone consult.  But I suspect the reason why he is doing those is because those are the two specific hormones I am low in.  He is also supplementing the other hormones specifically.  Your adrenals make other hormones and I think he likes to specifically dose the issues.  He himself takes DHEA for allergies.  He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.  Buist

[Guest guest]

Generally speaking, pregnenolone leads to increased DHEA and progesterone, not cortisol.LizOn Mar 22, 2006, at 5:03 AM, Irene.M@... wrote: Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to use and let the body make its own cortisol. Irene At 04:06 AM 3/22/2006, you wrote: >>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef? Just curious. Thanks Jingles<<<   No we did not discuss that.  We didn't discuss "why" on anything which is part of the problem with a short phone consult.  But I suspect the reason why he is doing those is because those are the two specific hormones I am low in.  He is also supplementing the other hormones specifically.  Your adrenals make other hormones and I think he likes to specifically dose the issues.  He himself takes DHEA for allergies.  He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.   Buist

[Guest guest]

What makes you say that? Pregnenelone is a precursor of progesterone and

DHEA as well. Why do you think that is the preferred pathway?

Irene

At 11:38 AM 4/13/2006, you wrote:

Generally speaking,

pregnenolone leads to increased DHEA and progesterone, not

cortisol.

Liz

On Mar 22, 2006, at 5:03 AM,

Irene.M@...

wrote:

Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to use and let the body make its own cortisol.

Irene

At 04:06 AM 3/22/2006, you wrote:

>>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef?

Just curious.

Thanks

Jingles<<<

No we did not discuss that. We didn't discuss " why " on anything which is part of the problem with a short phone consult. But I suspect the reason why he is doing those is because those are the two specific hormones I am low in. He is also supplementing the other hormones specifically. Your adrenals make other hormones and I think he likes to specifically dose the issues. He himself takes DHEA for allergies. He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.

Buist

[Guest guest]

Experimental data has shown that pregnenolone is more likely to increase levels of DHEA and progesterone -- not cortisol. Remember, you cannot assume the bio-synthesis from hormone to hormone that takes place in the adrenal gland and the gonads, etc. also take place when a substance is applied from the outside. The reactions that take place that changes one substance into another depend on specific enzymes -- and more than likely those enzymes are not available just anywhere in the body.Here's a short and I think fairly accurate review: http://www.bodyandfitness.com/Information/Womenhealth/Research/pregnenolone.htmIf anything I think pregnenolone is supposed to modulate the harmful effects of cortisol -- especially cortisol's damaging effects on the hippocampus and memory.LizOn Apr 13, 2006, at 2:26 PM, Irene.M@... wrote: What makes you say that? Pregnenelone is a precursor of progesterone and DHEA as well. Why do you think that is the preferred pathway? Irene At 11:38 AM 4/13/2006, you wrote: Generally speaking, pregnenolone leads to increased DHEA and progesterone, not cortisol. Liz On Mar 22, 2006, at 5:03 AM, Irene.M@... wrote: Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to use and let the body make its own cortisol. Irene At 04:06 AM 3/22/2006, you wrote: >>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef? Just curious. Thanks Jingles<<<   No we did not discuss that.  We didn't discuss "why" on anything which is part of the problem with a short phone consult.  But I suspect the reason why he is doing those is because those are the two specific hormones I am low in.  He is also supplementing the other hormones specifically.  Your adrenals make other hormones and I think he likes to specifically dose the issues.  He himself takes DHEA for allergies.  He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.   Buist

[Guest guest]

I knew that you can't make assumptions on what pathway a hormone will

take, that is why I wondered why you thought there was a preference for

DHEA over cortisol. Perhaps that is why I did so badly on

pregnenolone and very well on cortisol.

Thanks,

Irene

At 03:55 PM 4/13/2006, you wrote:

Experimental data has shown

that pregnenolone is more likely to increase levels of DHEA and

progesterone -- not cortisol. Remember, you cannot assume the

bio-synthesis from hormone to hormone that takes place in the adrenal

gland and the gonads, etc. also take place when a substance is applied

from the outside. The reactions that take place that changes one

substance into another depend on specific enzymes -- and more than likely

those enzymes are not available just anywhere in the body.

Here's a short and I think fairly accurate review:

http://www.bodyandfitness.com/Information/Womenhealth/Research/pregnenolone.htm

If anything I think pregnenolone is supposed to modulate the harmful

effects of cortisol -- especially cortisol's damaging effects on the

hippocampus and memory.

Liz

On Apr 13, 2006, at 2:26 PM,

Irene.M@...

wrote:

What makes you say that? Pregnenelone is a precursor of progesterone and DHEA as well. Why do you think that is the preferred pathway?

Irene

At 11:38 AM 4/13/2006, you wrote:

Generally speaking, pregnenolone leads to increased DHEA and progesterone, not cortisol.

Liz

On Mar 22, 2006, at 5:03 AM, Irene.M@... wrote:

Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to use and let the body make its own cortisol.

Irene

At 04:06 AM 3/22/2006, you wrote:

>>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef?

Just curious.

Thanks

Jingles<<<

No we did not discuss that. We didn't discuss " why " on anything which is part of the problem with a short phone consult. But I suspect the reason why he is doing those is because those are the two specific hormones I am low in. He is also supplementing the other hormones specifically. Your adrenals make other hormones and I think he likes to specifically dose the issues. He himself takes DHEA for allergies. He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.

Buist

[Guest guest]

Thanks for the article it was interesting. But it does not discuss

pregnenolone being more likely to convert to DHEA than cortisol.

Irene

At 03:55 PM 4/13/2006, you wrote:

Experimental data has shown

that pregnenolone is more likely to increase levels of DHEA and

progesterone -- not cortisol. Remember, you cannot assume the

bio-synthesis from hormone to hormone that takes place in the adrenal

gland and the gonads, etc. also take place when a substance is applied

from the outside. The reactions that take place that changes one

substance into another depend on specific enzymes -- and more than likely

those enzymes are not available just anywhere in the body.

Here's a short and I think fairly accurate review:

http://www.bodyandfitness.com/Information/Womenhealth/Research/pregnenolone.htm

If anything I think pregnenolone is supposed to modulate the harmful

effects of cortisol -- especially cortisol's damaging effects on the

hippocampus and memory.

Liz

On Apr 13, 2006, at 2:26 PM,

Irene.M@...

wrote:

What makes you say that? Pregnenelone is a precursor of progesterone and DHEA as well. Why do you think that is the preferred pathway?

Irene

At 11:38 AM 4/13/2006, you wrote:

Generally speaking, pregnenolone leads to increased DHEA and progesterone, not cortisol.

Liz

On Mar 22, 2006, at 5:03 AM, Irene.M@... wrote:

Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to use and let the body make its own cortisol.

Irene

At 04:06 AM 3/22/2006, you wrote:

>>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef?

Just curious.

Thanks

Jingles<<<

No we did not discuss that. We didn't discuss " why " on anything which is part of the problem with a short phone consult. But I suspect the reason why he is doing those is because those are the two specific hormones I am low in. He is also supplementing the other hormones specifically. Your adrenals make other hormones and I think he likes to specifically dose the issues. He himself takes DHEA for allergies. He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.

Buist

[Guest guest]

Here's a reference that makes it more explicit: http://www.tidesoflife.com/pregprodhea.htmI am trying to find sources that don't entail sending pdfs.LizOn Apr 13, 2006, at 4:08 PM, Irene.M@... wrote: Thanks for the article it was interesting. But it does not discuss pregnenolone being more likely to convert to DHEA than cortisol. Irene At 03:55 PM 4/13/2006, you wrote: Experimental data has shown that pregnenolone is more likely to increase levels of DHEA and progesterone -- not cortisol. Remember, you cannot assume the bio-synthesis from hormone to hormone that takes place in the adrenal gland and the gonads, etc. also take place when a substance is applied from the outside. The reactions that take place that changes one substance into another depend on specific enzymes -- and more than likely those enzymes are not available just anywhere in the body. Here's a short and I think fairly accurate review: http://www.bodyandfitness.com/Information/Womenhealth/Research/pregnenolone.htm If anything I think pregnenolone is supposed to modulate the harmful effects of cortisol -- especially cortisol's damaging effects on the hippocampus and memory. Liz On Apr 13, 2006, at 2:26 PM, Irene.M@... wrote: What makes you say that? Pregnenelone is a precursor of progesterone and DHEA as well. Why do you think that is the preferred pathway? Irene At 11:38 AM 4/13/2006, you wrote: Generally speaking, pregnenolone leads to increased DHEA and progesterone, not cortisol. Liz On Mar 22, 2006, at 5:03 AM, Irene.M@... wrote: Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to use and let the body make its own cortisol. Irene At 04:06 AM 3/22/2006, you wrote: >>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef? Just curious. Thanks Jingles<<<   No we did not discuss that.  We didn't discuss "why" on anything which is part of the problem with a short phone consult.  But I suspect the reason why he is doing those is because those are the two specific hormones I am low in.  He is also supplementing the other hormones specifically.  Your adrenals make other hormones and I think he likes to specifically dose the issues.  He himself takes DHEA for allergies.  He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.   Buist

[Guest guest]

Thanks, don't sweat it. I was mostly curious because I hadn't heard that

before.

Irene

At 05:34 PM 4/13/2006, you wrote:

Here's a reference that

makes it more explicit:

http://www.tidesoflife.com/pregprodhea.htm

I am trying to find sources that don't entail sending pdfs.

Liz

On Apr 13, 2006, at 4:08 PM, Irene.M@... wrote:

Thanks for the article it was

interesting. But it does not discuss pregnenolone being more likely to

convert to DHEA than cortisol.

Irene

At 03:55 PM 4/13/2006, you wrote:

Experimental data has shown that

pregnenolone is more likely to increase levels of DHEA and progesterone

-- not cortisol. Remember, you cannot assume the bio-synthesis from

hormone to hormone that takes place in the adrenal gland and the gonads,

etc. also take place when a substance is applied from the outside. The

reactions that take place that changes one substance into another depend

on specific enzymes -- and more than likely those enzymes are not

available just anywhere in the body.

Here's a short and I think fairly accurate review:

http://www.bodyandfitness.com/Information/Womenhealth/Research/pregnenolone.htm

If anything I think pregnenolone is supposed to modulate the harmful

effects of cortisol -- especially cortisol's damaging effects on the

hippocampus and memory.

Liz

On Apr 13, 2006, at 2:26 PM,

Irene.M@...

wrote:

What makes you say that? Pregnenelone is a precursor of progesterone and DHEA as well. Why do you think that is the preferred pathway?

Irene

At 11:38 AM 4/13/2006, you wrote:

Generally speaking, pregnenolone leads to increased DHEA and progesterone, not cortisol.

Liz

On Mar 22, 2006, at 5:03 AM, Irene.M@... wrote:

Pregnenelone is a precursor of Cortisol. Many doctors feel it is safer to use and let the body make its own cortisol.

Irene

At 04:06 AM 3/22/2006, you wrote:

>>>>Did you discuss why he prefers pregnenolone + DHEA over Cortef?

Just curious.

Thanks

Jingles<<<

No we did not discuss that. We didn't discuss " why " on anything which is part of the problem with a short phone consult. But I suspect the reason why he is doing those is because those are the two specific hormones I am low in. He is also supplementing the other hormones specifically. Your adrenals make other hormones and I think he likes to specifically dose the issues. He himself takes DHEA for allergies. He said he had been on allergy meds and an inhaler since 5 years old and when he started taking DHEA he didn't have to take meds anymore.

Buist