Re: Iodoral dosing: Gracia/rT3

[Guest guest]

<OT> Skipper - I was having just this discussion with Val over on NTH

the other day. That was my understanding of rT3 as well - that it

interfered with the T3 receptors. She stated rT3 was biologically

inactive.

I pulled up some of the limited research that's out there for her.

What sources do you have for it? I'm wondering if you've come across

some more that I may have missed. Could you post them or email them to

me? Thanks!

The body generally doesn't waste energy on processes that have no

purpose. I'm sure there's a lot more to be discovered about rT3, T2,

T1 & the like. I came across a lot of studies the other day that T2

does indeed have a metabolic purpose. They're over on NTH & in the

Thyroid group files if any wants to take a look. </OT>

>>>You know, if you take too much Armour there's a braking mechanism,

and that's what rT3 is. (Inactive T4 gets excreted, or turns into

either active T3 or inactive rT3.) Some people on large doses of

Armour are simply turning too much of the T4 into rT3. Since rT3 may

interfere with the T3 receptors, it may be the effective dose of

thyroid hormone they are getting is a lot lower than they think.<<<<

[Guest guest]

>From: " jtb14789 " <jtb14789@...>

>

><OT> Skipper - I was having just this discussion with Val over on NTH

>the other day. That was my understanding of rT3 as well - that it

>interfered with the T3 receptors. She stated rT3 was biologically

>inactive.

When looking up earlier today what could possibly cause rT3 to be low, I

couldn't find that answer, but I found this -

http://www.drcranton.com/hrt/thyroid_hormone.htm

" It does this by converting T4 not to T3 but to reverse T3, or " rT3. " A

mirror image of true T3, rT3, has an empty iodine receptor on the reverse

side, which may bind tightly to thyroid receptors within cells. It may thus

blocks the action of normal T3 by denying it landing zones. "

I don't know if they have " real " references or not, that the rT3 binds

tightly to the thyroid receptors.

Yes, it does have a purpose. If one takes in or produces too much T4, it

keeps one from going hyperthyroid. If one suddenly undergoes the stress of

a famine, producing rT3 doesn't burn the fuel (food) as efficiently, so it

stops one from wasting away (losing weight) too quickly.

Also interesting that rT3 may not only take up T3 receptors, but compete

with T4 for de-iodinizing -

http://www.wilsonsthyroidsyndrome.com/eManual/Chapters/05WhyNotT4.cfm

" The enzyme 5'-deiodinase converts T4 to T3. It also converts RT3 to T2 (T2

is considered an inactive metabolite). Thus, T4 and RT3 compete for the

attention of the same deiodinating enzyme.

T4/RT3 preponderance can be problematic in two ways. First, it perpetuates

decreased T3 production. Second, it can compete with what T3 is produced, at

the level of the nuclear membrane receptor. "

Skipper

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[Guest guest]

If cortisol is high, reverse T3 also goes high as a defense

against catabolism. High cortisol breaks down the body, breaks

down muscle and bone, etc.

Another way the body tries to protect itself, slow down,

and buy time.

Carol

[Guest guest]

I've heard this too and it makes sense but I have high coritosl and my

RT3 that gets checked every year is below normal. Wonder how that

happened

jingles

>

> If cortisol is high, reverse T3 also goes high as a defense

> against catabolism. High cortisol breaks down the body, breaks

> down muscle and bone, etc.

>

> Another way the body tries to protect itself, slow down,

> and buy time.

>

> Carol

>

[Guest guest]

high cortisol is a symptom of adrenal burnout, a symptom that something is wrong hormonally. IMO cortisol and DHEA are needed, and I really don't trust conventional testing. I don't think adrenals are working "too well".

Gracia

I've heard this too and it makes sense but I have high coritosl and my RT3 that gets checked every year is below normal. Wonder how that happenedjingles>> If cortisol is high, reverse T3 also goes high as a defense> against catabolism. High cortisol breaks down the body, breaks> down muscle and bone, etc.> > Another way the body tries to protect itself, slow down,> and buy time.> > Carol>

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[Guest guest]

My free T3 is fine until I begin combining weightlifting with endurance

exercise, then my free T3 drops low and I become hypo with an elevated TSH.

This must be a response to cortisol. I haven't checked my rt3 but it probably

is elevated.

I found a somewhat expensive supplement yesterday that claims to clinically

fight the defense against catabolism caused by cortisol by using enzymes....

called Sorenzyme.

--- groupiestuff <groupiestuff@...> wrote:

> I've heard this too and it makes sense but I have high coritosl and my

> RT3 that gets checked every year is below normal. Wonder how that

> happened

>

> jingles

>

>

>

> >

> > If cortisol is high, reverse T3 also goes high as a defense

> > against catabolism. High cortisol breaks down the body, breaks

> > down muscle and bone, etc.

> >

> > Another way the body tries to protect itself, slow down,

> > and buy time.

> >

> > Carol

> >

>

>

>

>

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[Guest guest]

>From: <kennio@...>

>My free T3 is fine until I begin combining weightlifting with endurance

>exercise, then my free T3 drops low and I become hypo with an elevated TSH.

>This must be a response to cortisol. I haven't checked my rt3 but it

>probably

>is elevated.

>

>I found a somewhat expensive supplement yesterday that claims to clinically

>fight the defense against catabolism caused by cortisol by using

>enzymes....

>called Sorenzyme.

Phosphatidylserine lowers cortisol. It also helps with brain function.

Maybe it could be substituted for the phospholipid you take?

Actually, it is a phospholipid, but may have more of a cortisol lowering

effect than the one you're taking -

http://www.mwt.net/~drbrewer/brainfunction1.htm

" Research with the elderly has shown that the phospholipid supplement

phosphatidylserine (PS) in dosages of 300 mg a day for 60 days may play a

unique role in helping to restore a more normal anti-stress response in the

region of the brain, the hypothalamus, that initiates the fight-or-flight

stress response. This area of the brain works in harmony with the pituitary

and the adrenal glands in response to stress. This interactive system is

known as the HPAA (hypothalamic pituitary-adrenal-axis). "

The PS really helps my Irish-Indian wife, who suffers from high cortisol

effects otherwise. (She also takes magnesium, I don't have much use for

that myself, but she needs it, I got her started on both to lower her

cortisol levels.)

Also for whatever reason, honey is supposed to help with recovery from

exercise, and one of the reasons is that it helps lower cortisol -

http://www.honeyassociation.com/honeyhi_document.php?articleid=10080

" Scientists at the University of Memphis in Tennessee have found that honey

boosts the performance, endurance and recovery of athletes.

In a recent study, nine competitive cyclists who took glucose and honey

reduced their finishing times by up to three minutes with a six per cent

increase in the athletes’ average power.

Meanwhile tests on 39 weight trainers showed that those who took honey after

exercise had lower levels of cortisol, a hormone released when the muscles

are under stress. These findings suggest that honey may be the ideal

pick-me-up as well as a great source of energy.

Compared to other sugar sources, honey has also been found to keep levels of

blood sugar fairly constant.

So keep in life’s fast lane with a simple spoonful of honey, taken every

day. "

***********************************

The other thing about honey is it has all those micronutrients in it

(magnesium, potassium, iodine.)

Of course, if you listen to the sugar industry, eating honey isn't any

better than eating a teaspoon of table sugar.

Skipper

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[Guest guest]

rT3 is a controversial subject. There is a school of thought

that finds rT3 testing rather meaningless. Maybe the problem

is the test? maybe the theory?

Still we know that metabolism slows when a person fasts or

regularly doesn't get a critical mass of calories (starvation

diets). Cortisol goes up when fasting, rT3 might also, to

prevent the person from starving or wasting away,

at least buy some time til they might find more food in a

famine. This seems very plausible to me. The body doesn't know

the different between a crash diet and a famine. It does the

best it can with the resources at hand, and it tries to help

you survive.

As for measuring rT3, I have no direct experience with it.

All I have is a small amount of hearsay on both sides.

Carol

" groupiestuff " <groupiestuff@...> wrote:

>

> I've heard this too and it makes sense but I have high coritosl

> and my

> RT3 that gets checked every year is below normal. Wonder how that

> happened

>

> jingles

>

>

>

> >

> > If cortisol is high, reverse T3 also goes high as a defense

> > against catabolism. High cortisol breaks down the body, breaks

> > down muscle and bone, etc.

> >

> > Another way the body tries to protect itself, slow down,

> > and buy time.

> >

> > Carol

> >

>

[Guest guest]

>

> Why is cortisol high? Is it because your adrenals produce more,

or because

> you are hypothyroid and there's slower liver clearance of

cortisol, which

> makes it stay in your blood longer?

I'm not sure what came first. In hindsight I was hypothyroid at

around age 6 and wasn't treated until age 34. In my teens and early

20's when I was of normal weight, my muscles never toned and I was a

jock. Lifted weights and played varsity sports and intermural sports

for up to 10 hours a week. I was always flabby. Could have been

from being hypo or maybe from high cortisol or both. Due to some

joint problems I was diagnosed with an overactive sympathetic system

(could this have been high cortisol?). Just recently I could no

longer take the ARmour since my heart was beating too fast and I was

overstimulated along with a bunch or other problems caused by the

cortisol. My 24 hour urine test was about 80% outside the normal

range and I was told I had an overactive H-P-A axis from chronic

stress. I was given Biotics Research ADHS to control the cortisol

and it worked wonders. My liver tests have always been in normal

range and my Free T3 has always been in the upper part of the range

since being on Armour (not so on Synthroid). My RT3 is always BELOW

normal. I take 5 grains My TSH has always been negligible since

starting ARmour many years ago. Luckily I've never had a TSH doc

while on ARmour. I've been taking 50mg of Iodo Caps (same thing as

Iodoral just cheaper) since July. It does keep the goiter under

control but it doesn't do anything else that's noticeable.

jingles

>

>

[Guest guest]

Serious weight lifters and many professional athlets make too much

cortisol from the amount of excercise they do. Biotics Research is a

great product and many take PS. ....jingles

>

> My free T3 is fine until I begin combining weightlifting with

endurance

> exercise, then my free T3 drops low and I become hypo with an

elevated TSH.

> This must be a response to cortisol. I haven't checked my rt3 but

it probably

> is elevated.

>

> I found a somewhat expensive supplement yesterday that claims to

clinically

> fight the defense against catabolism caused by cortisol by using

enzymes....

> called Sorenzyme.

>

>

> --- groupiestuff <groupiestuff@...> wrote:

>

> > I've heard this too and it makes sense but I have high coritosl

and my

> > RT3 that gets checked every year is below normal. Wonder how

that

> > happened

> >

> > jingles

> >

> >

> >

> > >

> > > If cortisol is high, reverse T3 also goes high as a defense

> > > against catabolism. High cortisol breaks down the body, breaks

> > > down muscle and bone, etc.

> > >

> > > Another way the body tries to protect itself, slow down,

> > > and buy time.

> > >

> > > Carol

> > >

> >

> >

> >

> >

>

>

>

>

>

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>

> Online or Campus degree Associate's, Bachelor's, or Master's

> in less than one year.www.findtherightschool.com

>

[Guest guest]

>From: " Gracia " <circe@...>

>

> high cortisol is a symptom of adrenal burnout, a symptom that something

>is wrong hormonally. IMO cortisol and DHEA are needed, and I really

>don't trust conventional testing. I don't think adrenals are working " too

>well " .

> Gracia

I know some adrenal docs call high cortisol one of the first symptoms of

adrenal burn out, and they'll say it will eventually cause a crash.

I'm sure it's true in some cases, but not all.

You should have high cortisol if you're under stress. You're supposed to.

(Of course, eventually you'll crash and burn in this case.)

You should have high cortisol if you're in pain, because it's

anti-inflammatory and is a known marker for pain.

High cortisol can be caused by an adrenal or pituitary tumor.

In some people, taking DHEA actually lowers cortisol. But, not in all

cases.

Vitamin C and phosphatidylserine also lower cortisol levels, and maybe

magnesium does too as it helps you to relax. Cortisol pushes out magnesium,

which means those with high cortisol need to supplement magnesium for sure.

Those with high cortisol probably over react to sugar, chocolate or caffeine

products and shouldn't ingest them. Probably because cortisol raises the

blood sugar as it is, you don't need other things that do the same.

I believe iodine really helps the adrenals. It may be due to causing a

detox of mercury -

http://www.tuberose.com/Mercury.html

" Mercury accumulates in the adrenal glands and disrupts adrenal gland

function.

One of the largest tissue stores of vitamin C is the adrenals; it is

exceeded only by the level of vitamin C in the pituitary. "

Skipper

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[Guest guest]

Hi Jingles,

> I've been taking 50mg of Iodo Caps (same thing as

> Iodoral just cheaper) since July. It does keep the goiter under

> control but it doesn't do anything else that's noticeable.

Thanks for mentioning what form of iodine you take - I hadn't heard

of that product. I wanted to know what was in it and found this on a

retail site:

Iodide(Potassium Iodide) 7.5 mg

Iodine(Free Iodine) 5.0 mg

Potassium(Potassium Iodide) 2.4 mg

Gelatin Caps, Rice Powder, Magnesium Stearate.

(May contain silica and/or cellulose complex).

Free of wheat, milk, yeast, eggs, corn, soy,

sugar, table salt, artificial colors and

preservatives.

http://www.nurturemom.com/womens_health/0470.shtml

$17/bottle of 100 seems to be the most common price. I wonder what

Abrahams and the other would say on how it compares to Iodoral? Looks

very similar to me.

Thanks much,

Sharon

[Guest guest]

yeah I think this is all true. Best to look at the history and symptoms of a person.

Gracia

>From: "Gracia" <circe@...>>> high cortisol is a symptom of adrenal burnout, a symptom that something >is wrong hormonally. IMO cortisol and DHEA are needed, and I really >don't trust conventional testing. I don't think adrenals are working "too >well".> GraciaI know some adrenal docs call high cortisol one of the first symptoms of adrenal burn out, and they'll say it will eventually cause a crash.I'm sure it's true in some cases, but not all.You should have high cortisol if you're under stress. You're supposed to. (Of course, eventually you'll crash and burn in this case.)You should have high cortisol if you're in pain, because it's anti-inflammatory and is a known marker for pain.High cortisol can be caused by an adrenal or pituitary tumor.In some people, taking DHEA actually lowers cortisol. But, not in all cases.Vitamin C and phosphatidylserine also lower cortisol levels, and maybe magnesium does too as it helps you to relax. Cortisol pushes out magnesium, which means those with high cortisol need to supplement magnesium for sure.Those with high cortisol probably over react to sugar, chocolate or caffeine products and shouldn't ingest them. Probably because cortisol raises the blood sugar as it is, you don't need other things that do the same.I believe iodine really helps the adrenals. It may be due to causing a detox of mercury -http://www.tuberose.com/Mercury.html"Mercury accumulates in the adrenal glands and disrupts adrenal gland function.One of the largest tissue stores of vitamin C is the adrenals; it is exceeded only by the level of vitamin C in the pituitary. "Skipper__________________________________________________________MSN Shopping has everything on your holiday list. Get expert picks by style, age, and price. Try it! http://shopping.msn.com/content/shp/?ctId=8000,ptnrid=176,ptnrdata=200601 & tcode=wlmtagline

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