Re: Re:oxidative liver impairment upregulates EtG production....

[Guest guest]

thanks Robin....I take a sh--load of meds, so here goes. Novolog Insulin,30u tid, levimir insulin, 42u bid, metformin 1000mg, daily,actos 30mg daily, tricor 145mg daily, vitorin 10/20 daily,lisinopril 20mg daily and wellbutrin 300mg daily. autofermentation? the problem I am encountering is that so little research has been conducted in general, much less in specific to diabetes that it's difficult to find documentation of these. my etg was 1600!!! what the hell could have caused that? Has to be related to the glucose, this is not an incidental exposure level, or maybe it is, I don't know....jessrobin murray <remurraymd@...> wrote: hi j,if you could be specific on your meds we could check and see if they impair liver oxidative systems upregulating EtG...also severe uncontrolled diabetes causes impaired liver function a lot...also hyperosmolar syndrome seen a lot with brittle diabetics,might have a role..diabetics i have know have had positives ascribed to autofermentation also..good that you have a helpful addictionologist in recovery... i would not spend 90 days in a rehab for a false positive experimental non-approved EtG... i would check lfts and meds..odds are you are upregulating due to liver impairment of oxidative metabolism causing increased glucuronide conjugation hence invreased Etg.. regards,r High <jess4111 > wrote: Hello Robin...I just saw the addictionologist and he's very supportive...he's in recovery. He is focusing on my blood sugar numbers which have been 300-500., which may have caused a high etg level do you know of or does anyone on this site know of any studies done with diabetes with bs numbers that high. The case manager tried to tell me that there was no sugar in my urine but both the Dr. and I looked at the report and it didn't even show where they tested sugar in the urine. i just tested my bs and it's 358. I went out and bought a glucose/ketones for urine testing and the sugar level was over 2000. I was hospitalized 2 days prior to dropping the pos etg urine with a bs of 600.I have extreme resistance to insulin, therefore brittle diabetes. Please, if anyone knows of reearch re: etg and poorly controlled diabetes, please let me know. My case

depends on it since they aren't even focusing on "incidental pos", why I don't know....Jessrobin murray <remurraymd > wrote: truly independent addictionologists are hard to find...they will privately share what they may may not share in public...addictiologists in recovery have helped me the most... kevin maccauley comes to mind...if you ever get a chance to hear him speak do not miss it..awesome..regards, crssemcaol wrote: Hey ~ MRO are of no help either. Isn't it sad tht those in the Government are turning thier backs on us or just not listening the the people? Re: Re:?NMS troll connection... not all of us have MRO's some of us have the courts or social workers that got an associates degree from Nigeria , they know nothing about the whys and how's of liver function and etg..for a matter of fact in my case I wasn't tested for creatine at all nor was I told to sign a contract with things to avoid..and I am not afraid of anyone but my government..They have taken all already. Dumb A**es. Do not think I don't LOVE my country. I do!!! Check out the new AOL. Most comprehensive set of free safety and security tools, free access to millions of high-quality videos from across the web, free AOL Mail and more. Don't pick lemons.See all the new 2007 cars at Autos.

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[Guest guest]

wow...interesting. I have been dx w/ fatty infiltrates into the liver. thanks for being so knowledgeable!!!!robin murray <remurraymd@...> wrote: The Liver in Diabetes Although liver function tests are commonly abnormal in patients with diabetes, it is unclear whether this is a reflection of the underlying obesity that is so common in patients with type 2 diabetes or whether it is an effect of poorly controlled diabetes. Fatty infiltration of the liver

(nonalcoholic steatohepatitis) is common in obese individuals (up to 90%) as well as in type 2 diabetic individuals (up to 75%). People with type 1 diabetes in very poor control may also develop this syndrome, although it is much less common. Fatty infiltration of the liver may lead to tender hepatomegally, elevated liver enzyme tests, and abdominal pain syndromes. Occasionally, this may progress to fibrosis and cirrhosis of the liver. The diagnosis is usually suspected on the basis of the clinical presentation but can be confirmed with abdominal ultrasonography and, if needed, percutaneous liver biopsy. Metabolic abnormalities such as hemochromatosis and infectious etiologies such as viral hepatitis need to be excluded as part of the evaluation. robin murray <remurraymd > wrote: hi j,if you could be specific on your meds we could check and see if they impair liver oxidative systems upregulating EtG...also severe uncontrolled diabetes causes impaired liver function a lot...also hyperosmolar syndrome seen a lot with brittle diabetics,might have a role..diabetics i have know have had positives ascribed to autofermentation also..good that you have a helpful addictionologist in recovery... i would not spend 90 days in a rehab for a false positive experimental non-approved EtG... i would check lfts and meds..odds are you are upregulating due to liver impairment of oxidative metabolism causing increased glucuronide conjugation hence invreased Etg.. regards,r High <jess4111 > wrote: Hello Robin...I just saw the addictionologist and he's very supportive...he's in recovery. He is focusing on my blood sugar numbers which have been 300-500., which may have caused a high etg level do you know of or does anyone on this site know of any studies done with diabetes with bs numbers that high. The case manager tried to tell me that there was no sugar in my urine but both the Dr. and I looked at the report and it didn't even show where they tested sugar in the urine. i just tested my bs and it's 358. I went out and bought a glucose/ketones for urine testing and the sugar level was over 2000. I was hospitalized 2 days prior to dropping the pos etg urine with a bs of 600.I have extreme resistance to insulin, therefore brittle diabetes. Please, if anyone knows of reearch re: etg and poorly controlled diabetes, please let me know. My case depends on it since they

aren't even focusing on "incidental pos", why I don't know....Jessrobin murray <remurraymd > wrote: truly independent addictionologists are hard to find...they will privately share what they may may not share in public...addictiologists in recovery have helped me the most... kevin maccauley comes to mind...if you ever get a chance to hear him speak do not miss it..awesome..regards, crssemcaol wrote: Hey ~ MRO are of no help either. Isn't it sad tht those in the Government are turning thier backs on us or just not listening the the people? Re: Re:?NMS troll connection... not all of us have MRO's some of us have the courts or social workers that got an associates degree from Nigeria , they know nothing about the whys and how's of liver function and etg..for a matter of fact in my case I wasn't tested for creatine at all nor was I told to sign a contract with things to avoid..and I am not afraid of anyone but my government..They have taken all already. Dumb A**es. Do not think I don't LOVE my country. I do!!! Check out the new AOL. Most comprehensive set of free safety and security tools, free access to millions of high-quality videos from across the web, free AOL Mail and more. Don't pick lemons.See all the new 2007 cars at Autos.

Everyone is raving about the all-new beta.