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Pneumocystis: Pneumocystis jiroveci (previously classified as Pneumocystis

carinii), the _fungus_

(http://www.medterms.com/script/main/art.asp?articlekey=3527) that causes

pneumocystis _pneumonia_

(http://www.medterms.com/script/main/art.asp?articlekey=450) (_PCP_

(http://www.medterms.com/script/main/art.asp?articlekey=4806) ). Pneumocystis

jiroveci is found worldwide, in humans

and animals. Serologic evidence indicates that most healthy children have been

exposed to it by age 3 to 4. Pneumocystis _pneumonia_

(http://www.medterms.com/script/main/art.asp?articlekey=450) (PCP) occurs in

immunosuppressed

individuals and in premature, malnourished infants.

The symptoms of Pneumocystis pneumonia (PCP) include _dyspnea_

(http://www.medterms.com/script/main/art.asp?articlekey=3145) (difficulty

breathing),

nonproductive _cough_

(http://www.medterms.com/script/main/art.asp?articlekey=33174#) , and fever.

Chest X-rays show infiltrates in both lungs. Typically, in

untreated PCP, increasing _pulmonary_

(http://www.medterms.com/script/main/art.asp?articlekey=5123) involvement

leads to death.

Pneumocystosis is one of the most common infections in

immunosuppressed patients with AIDS.

P.jiroveci: the infection has a world-wide distribution

and the transmission seems to occur by airborne route.

The organims that causes human pneumocystosis is

now named Pneumocystis jiroveci * Frenkel 1999,

in honor of the Czech parasitologist Otto Jirovec.

The organism is now considered a fungus,

based on nucelic acid and biochemical analysis; nevertheless,

on the basis of morpholocic and biologic characterisitcs

it is included in the atlas of medical parasitology