Pharmacology Question

July 16, 2010

Here is a Pharmacology question I just made for my class:

1. Which would be used to treat a GI Ulcer:

A. Zyrtec/penicillin

B. Zantac/miochol

C. Inderal/hyoscamine

D. glycopyrrolate/ranitidine

2.

A. Antihistamine/antibiotic

B. H2 Antagonist/Cholinergic

C. beta blocker/belladonna derrivative

D. antimuscarinic/H2 Antagonist

What do you think the correct/best answer is?

Jeanetta Mastron CPhT BS

Founder/Owner

July 16, 2010

Jeanetta !

Your question may too general as treatment protocols are established based on

type of GI ulcer. If we see H-Pylori bacteria involvement which is commonplace,

then an antibiotic such as Clarithromycin is used along with medication to

inhibit the secretion of stomach acid from the parietal cells such as an

Histamine 2 or H2 antagonist or blocker. Older medications such as your

anticholinergics work as well. If we see no involvement of H-Pylori, then an H2

Blocker and anticholinergic or antispasmodic would work fine.

So without being specific enough I would use 1. D or 2. D as the majority of

antimuscarinic's are anticholinergics.

Great Question!

Joe

-----------

Here is a Pharmacology question I just made for my class:

1. Which would be used to treat a GI Ulcer:

A. Zyrtec/penicillin

B. Zantac/miochol

C. Inderal/hyoscamine

D. glycopyrrolate/ranitidine

2.

A. Antihistamine/antibiotic

B. H2 Antagonist/Cholinergic

C. beta blocker/belladonna derrivative

D. antimuscarinic/H2 Antagonist

What do you think the correct/best answer is?

Jeanetta Mastron CPhT BS

Founder/Owner

July 16, 2010

Great answer Joe.

D IS the correct answer for THESE questions with THESE set of possible answers.

(1.D and 2.D)

Allow me to say however, without the diagnosis or type of GI ulcer written into

the question the pharmacy technician should still be able to pick out the BEST

possible answer for a GI ulcer. Since the technician should also know causes,

factors or types of GI ulcers, he or she should be able to pick out the

combination listed that works, as only one combination does. Process of

elimination can also be used on a test, but on the job the tech should know

which drugs are used for which disease states. I liken this to my using

the word 'antimuscarinic' in my question,as I teach my students that either

antimuscarinic or anticholinergic can be used, yet I usually use the term

anticholinergic. They still have to know it!

To include a H,Pylori in the question, which is the MOST common cause of GI

Ulcers, the possible answer set would have to include a PPI and a 'Macrolide'

Antibiotic that is used in Dual or Triple Therapy for GI ulcers caused by H.

Pylori.

Some GI ulcers are caused by stress, use of medications such as NSAIDS when COX

I is inhibited and other reasons which do not include H. Pylori. In this case

the original questions and answers of 1D and 2D would prevail.

Here is an other version of the question with the specific type of GI Ulcer

mentioned:

1. Which would be used to treat a GI Ulcer caused by H.Pylori:

A. Zyrtec/penicillin

B. Zantac/miochol

C. Inderal/hyoscamine

D. omeprazole/clarithromycin

2.

A. Antihistamine/penicillin antibiotic

B. H2 Antagonist/Cholinergic

C. beta blocker/belladonna derrivative

D. proton pump inhibitor/macrolide antibiotic

In this case with THESE questions and THESE sets of answers the answer is D

(1. D. and

2. D)

Since H. Pylori is an infection an antibiotic needs to be used to eradicate the

bacteria. However it must be a tried and true Antibiotic. PCN does not work in

this case. YES, newbies, the tech should know this. Thus A is not the correct

answer.

Newbies or those studying for the PTCB exam please feel free to post your

comments

or questions. These are pharmacology type questions.

Respectfully,

Jeanetta Mastron CPhT BS

Founder/Owner

From: Joe M <joemedina@...>

Subject: Re: Pharmacology Question

Date: Friday, July 16, 2010, 2:33 PM