Fw: [msalternatives] Fwd: World of MS Update Service

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From: " Jooly's Joint " <jooly@...>

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<msalternatives >; <nurseswithms >

Sent: Wednesday, May 12, 2004 1:41 PM

Subject: [msalternatives] Fwd: World of MS Update Service

>

> >

> >World of MS Update Service, 11 May 2004

> >====================

> >

> >World of MS Update Service

> >

> >Research News

> >====================

> >

> >Elevated white matter myo-inositol in clinically isolated syndromes

> >suggestive of multiple sclerosis

> >--------------------

> >Metabolite concentrations were obtained in the normal appearing white

> >matter of 96 patients after onset of a clinically isolated syndrome (CIS)

> >suggestive of multiple sclerosis and in 44 healthy control subjects.

> >Patients showed elevated concentration of Inositol, which may reflect a

> >process of pathogenic importance in multiple sclerosis.

> >

> >http://www.msif.org/goemail.rm?id=187

> >

> >

> >Dysphagia and multiple sclerosis

> >--------------------

> >This paper reviews pathogenesis, diagnosis and treatment of neurogenic

> >dysphagia in MS.

> >

> >http://www.msif.org/goemail.rm?id=188

> >

> >

> >Combination Therapy for Multiple Sclerosis

> >--------------------

> >Preliminary clinical trials suggest that combination therapy in MS does

not

> >increase the side-effects of approved monotherapy. Therefore its efficacy

> >over monotherapy should be tested.

> >

> >http://www.msif.org/goemail.rm?id=189

> >

> >

> >Paraclinical support of the person diagnosed with multiple sclerosis

> >--------------------

> >The author suggests a model of paraclinical support for people with MS

and

> >their family and friends, during and post-diagnosis.

> >

> >http://www.msif.org/goemail.rm?id=190

> >

> >

> >Multicentre, randomised, double blind, placebo controlled, phase III

study

> >of weekly, low dose, subcutaneous interferon beta-1a in secondary

> >progressive multiple sclerosis

> >--------------------

> >This multicentre, double blind, placebo controlled study examined the

> >clinical benefit of low dose IFN beta-1a, 22 mcg subcutaneously once

> >weekly, in 371 patients with secondary progressive MS. Treatment had no

> >beneficial effect on time to confirmed progression on either the EDSS or

> >the Regional Functional Status Scale.

> >

> >http://www.msif.org/goemail.rm?id=191

> >

> >

> >Clinical characteristics of multiple sclerosis in Vasterbotten County in

> >northern Sweden

> >--------------------

> >This study presents data derived from two population-based multiple

> >sclerosis populations, an incidence cohort and a prevalence population,

> >from Vasterbotten County, northern Sweden. Based on the comparison of

> >present and earlier natural history data, multiple sclerosis appears to

be

> >a slightly more benign disease than previously recognised.

> >

> >http://www.msif.org/goemail.rm?id=192

> >

> >

> >Multiple sclerosis associated with neurofibromatosis type I

> >--------------------

> >Association between neurofibromatosis type 1 (NF-1) and multiple MS has

> >been very rarely described. The authors report the case of a 40-year-old

> >woman with familial NF-1 since childhood, who developed MS.

> >

> >http://www.msif.org/goemail.rm?id=193

> >

> >

> >Epstein-Barr virus in pediatric multiple sclerosis

> >--------------------

> >Serological evidence for remote Epstein-Barr Virus (EBV) infection was

> >present in 83% of pediatric MS patients compared with 42% of emergency

> >department and healthy controls, suggesting an association between EBV

> >infection and pediatric MS.

> >

> >http://www.msif.org/goemail.rm?id=194

> >

> >

> >Deep brain stimulation in the management of neuropathic pain and multiple

> >sclerosis tremor

> >--------------------

> >This paper demonstrates that with careful patient selection, deep brain

> >stimulation of the central gray matter can offer significant functional

> >benefit in patients with multiple sclerosis tremor.

> >

> >http://www.msif.org/goemail.rm?id=195

> >

> >

> >MS Society News

> >====================

> >

> >Canadian researchers to study children to uncover the triggers of MS

> >--------------------

> >A ground-breaking study aims to identify the key triggers which cause MS.

> >This global-first study of MS in children will provide unique insights

into

> >the disease. The MS Scientific Research Foundation and the Multiple

> >Sclerosis Society of Canada recently announced funding for this

> >cross-Canada research project.

> >

> >http://www.msif.org/goemail.rm?id=196

>

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