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Tuesday, May 18, 2004

Home > Multiple Sclerosis > ReVia etc. (Naltrexone)

ReVia etc. (Naltrexone)ReVia (Naltrexone) is an opiate-receptor blocker medication that is approved for the treatment of alcohol dependence (U.S. FDA). Naltrexone is also used to block the effects of narcotics. Although clinical studies are lacking, some physicians believe that low dose Naltrexone (LDN) may be helpful for individuals with auto-immune disorders. The theory is that LDN may stimulate the pituitary to increase the production and release of endorphins, which helps to regulate the immune system. The therapeutic dosage range for LDN is from 1.50 mg. to 4.5 mg. every night. Dosages below this range are likely to have no effect at all, and dosages above this range are likely to block endorphins for too long a period of time and interfere with its effectiveness. NOTE: Low dose Naltrexone needs to be acquired from a compounding pharmacy (they either grind up the 50 mg. tablets of naltrexone to prepare the LDN capsules, or use naltrexone, purchased as a powder, from a primary manufacturer).

AVERAGE MEMBER RATINGSbased on 55 ratings (0 = poorest; 10 = best)

Weighted ?

9.3

Effectiveness

9

Lack of Side Effects

9.6

Ease of Use

9.9

Effective After Long Term Use

9.2

Cost Effectiveness

9.4

INDIVIDUAL MEMBER RATINGS

just_friday_now (1)[sydney,NSW - Australia] 5/16/2004 8:05:51 AM

10

Best for MSNever have I taken medication for my condition (MS) and I have Primary Progressive MS. Since starting LDN, I feel like a revitalised person, with hope for my health's future and in just a short time, i have improved greatly. I use a wheelchair, but ...[Read More]

Dosage: 3 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: one weekBrand: ReVia

1 members found this rating helpful. Was this rating helpful to you?

KathyW (5)[south Plainfield,NJ - United States] 5/9/2004 4:34:12 PM

9.7

NaltrexoneI had been thinking about getting a prescription for Naltrexone for almost a year. From what I read it really sounded too good to be true. I was a bit scared/hesitant but now I am SO HAPPY that I finally started taking this drug. I am showing impr...[Read More]

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: one monthBrand: Naltrexone (generic)

2 members found this rating helpful. Was this rating helpful to you?

child of God (0)[Heath ohio - United States] 5/2/2004 4:28:46 PM

8.5

ONLY GETTING BETTERSINCE I HAVE STARTED LDN, MY EYE HAS SHOWN SOME IMPROVEMENT. MY ENERGY IS STILL LACKING. I HAVE HAD M.S. SINCE DEC. 2001 AND HAVE NEVER TAKEN ANY ABCR DRUGS OR STEROIDS. I WAS FINE UP UNTIL 6 WEEKS AGO. I WOKE UP DIZZY AND COULDN'T STAND FOR 2 DA...[Read More]

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several weeksBrand: Naltrexone (generic)

0 members found this rating helpful. Was this rating helpful to you?

SusieJo (3)[Reading, PA - United States] 4/20/2004 3:14:15 PM

10

naltrexoneI believe this medicine has stopped the progression. I have more energy, my eyes are good,and my singing voice has returned. Leg spasms are lessened. This is wonderful news for all who have MS.

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several monthsBrand: Naltrexone (generic)

2 members found this rating helpful. Was this rating helpful to you?

Suetolod (6)[waterford, ct - United States] 4/20/2004 12:50:14 PM

10

less stiffness, more energyi have had MS since 1993. tried Beterseron got worse. went on Avonex in 2000. I have 2 small lessions on brain, they have never changed but I have progressed from walking to cane to wheelchair. I decided to try LDN I started April 1st. After 20 da...[Read More]

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: one monthBrand: Naltrexone (generic)

6 members found this rating helpful. Was this rating helpful to you?

ms_withattitude (3)[Calgary - Canada] 4/19/2004 6:23:46 PM

10

LDN works greatI have been taking Low Dose Naltrexone for 2 years and I have not progressed at all, in fact I have only improved. I got my life back again.

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several yearsBrand: Naltrexone (generic)

1 members found this rating helpful. Was this rating helpful to you?

gatorgirl (10)[ville, Florida - United States] 4/19/2004 3:52:36 PM

9.7

It really worksI have had MS for 8 years and have chronic neck pain, numbness, and spasms. I was having exercerbations every year like clock work. My father who is an anesthesiologist did some research and spoke to a top pain specialist on the drug Naltrexone for M...[Read More]

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several yearsBrand: Naltrexone (generic)

5 members found this rating helpful. Was this rating helpful to you?

Molina (16)[Cambridge, Ma - United States]Rating Updated! 4/17/2004 9:18:56 AM

9.4

First Sign of Hope Since my DiagnosisThis is a second update - I've been on LDN now for only two weeks, to my AMAZEMENT still absolutely no side effects. In the past 10 months I have been slowly losing my ability to do several things I was still able to do eg. ride a bike (although walk...[Read More]

Dosage: 3 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several daysBrand: Naltrexone (generic)

6 members found this rating helpful. Was this rating helpful to you?

SammyJo (4) 4/16/2004 2:35:26 PM

10

LDN works for me / LDN surveyI just saw my neurologist, who was happy to presrcibe LDN for me after seeing how well I was doing after 2 months at 4mg. I showed this survey to him, and he is going to take this to the MS research team, at the university medical school hospital I g...[Read More]

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several monthsBrand: (Other - not listed here)

4 members found this rating helpful. Was this rating helpful to you?

Maupiti (3)[New York - United States] 3/27/2004 12:15:35 PM

9.4

LDN - some kind of wonderfulSince I started LDN in February, 2004 for MS, I have had a remarkable improvement of my symptoms - spasticity, stamina, especially. And what's really funny is that everyone around me noticed a rapid change in me as well (I had no idea how bad I loo...[Read More]

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several monthsBrand: Naltrexone (generic)

3 members found this rating helpful. Was this rating helpful to you?

forgivenbyHim (2)[Norristown, PA - United States]Rating Updated! 3/26/2004 6:00:26 PM

10

Naltrexone RulesRemedy is not the right description for there is no remedy because there is no known cause of MS. But I am so glad that I learned about Naltrexone. The science of its efficacy is fairly easy to understand compared to the science of the high-powered ...[Read More]

Dosage: 3 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: one yearBrand: Naltrexone (generic)

2 members found this rating helpful. Was this rating helpful to you?

janecy (2)[Pompton Plains, NJ - United States]Rating Updated! 3/22/2004 5:30:40 PM

8.9

LDN for MSI am the first patient, for my neurooogist, to go on LDN. Presently my pharmacist is switching to avicel as a filler so I will 'start over' at 3mg and hopefully see the results others have experienced. I'm looking forward to it!My neuro now has sev...[Read More]

Dosage: 3 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: one yearBrand: Naltrexone (generic)

2 members found this rating helpful. Was this rating helpful to you?

dtick356 (1) 3/11/2004 9:30:40 PM

9.9

i am impressedi haven't noticed any changes in my symptoms, but i have been exacerbation free for 2 years, also i have not been sick with any kinds of cold or flu.

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several yearsBrand: Naltrexone (generic)

1 members found this rating helpful. Was this rating helpful to you?

Mardea (6)[braintree, Mass - United States] 3/10/2004 1:16:23 PM

9.5

Low Dose NaltrexoneI have been on LDN since June 2003. This is the best that I have felt in the 27 years that I have had MS. My muscle spasms have eased up considerably, so that I have been able to cut the dose of muscle relaxant in half. I used to get numbness in my...[Read More]

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: several monthsBrand: Naltrexone (generic)

6 members found this rating helpful. Was this rating helpful to you?

zillba (5)[ City , TN - United States] 2/25/2004 7:44:51 PM

8.2

LDNAll I can say is the cane that was forever in my hand is now hanging on a hook on the wall and has been there for weeks. I still would not pass a road side drunk test but I walk pretty good, lots of the tingly stuff is gone, bladder control better, a...[Read More]

Dosage: 4.5 mg. (diluted from 50 mg. capsule)Frequency: 1 dose 1 x dayTotal Length: one monthBrand: Naltrexone (generic)

5 members found this rating helpful. Was this rating helpful to you?

2 3 4 Next 15 Ratings

Brands:(Other - not listed here)NalorexNaltrexone (generic)ReVia

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What's Related:Low Dose NaltrexoneHelpful information on how low dose Naltrexone may help with autoimmune diseases like MS. Also includes a list of compounding pharmacies where LDN may be supplied.

Histamine and Alternative MS TherapiesHelpful message board for LDN and other non-conventional MS therapies.

Naltrexone in the treatment of alcohol dependenceFall 2002. In this Canadian study, 120 alcohol-dependent individuals were assessed to receive treatment with 50 mg of naltrexone orally for 12 weeks in an open-label trial. 54% of the subjects completed the entire 12 weeks of treatment. During the study, 39% of patients abstained, while of the individuals reporting drinking at baseline, 86% were consuming less alcohol by their final visit.

Naltrexone in the treatment of alcohol use disorders in patients with concomitant major mental illness2000. In this study of 72 mentally ill outpatients treated with naltrexone for alcohol use disorders. Of those who took Naltrexone for at least eight weeks, 82% reduced their drinking by at least 75%, and only 17% relapsed at eight weeks. The authors conclude that naltrexone is useful in the treatment of dually-disordered patients.

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