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Vitamin C Reduces C-rp?

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Hi folks:

" Researchers at the University of California say that participants

who took about 500 milligrams of vitamin C supplements per day saw a

24 per cent drop in plasma C-reactive protein (CRP) levels after two

months. Recent research suggests that CRP may be a better predictor

of heart disease than cholesterol levels. "

http://www.nutraingredients-usa.com/news/news-NG.asp?id=51369

http://snipurl.com/9adh

(Guess what else **dramatically** reduces C-rp? ; ^ ))))

Rodney.

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Here is the underlying study:

http://tinyurl.com/49ztg]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=15047680

PMID: 15047680

Subjects were only tested after the two months were over, so the beneficial effect might have occurred at any time up until then. Maybe it even happens immediately.

Also, C + other anti-oxidants together had no effect.

OTOH, fish oil did not reduce hr CRP:

http://snipurl.com/9ao8

PMID: 15100717

"The median CRP change in the fish oil group did not significantly differ from that in the placebo group... CONCLUSION:: The currently available data -including ours- do not support that beneficial effects on CRP are involved in a mechanism explaining the protective effect on heart disease risk of n-3 fatty acids as present in fish"

In a message dated 9/23/04 2:27:06 PM Eastern Daylight Time, perspect1111@... writes:

"Researchers at the University of California say that participants

who took about 500 milligrams of vitamin C supplements per day saw a

24 per cent drop in plasma C-reactive protein (CRP) levels after two

months. Recent research suggests that CRP may be a better predictor

of heart disease than cholesterol levels. "

http://www.nutraingredients-usa.com/news/news-NG.asp?id=51369

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In a message dated 9/23/04 10:39:14 PM Eastern Daylight Time, perspect1111@... writes:

That is a bit odd. It seems to suggest that the other anti-oxidants

neutralize the benefit of the vitamin C. Very interesting (if true).

Odd, indeed - and the authors say ""However, the only other study to administer vitamin C and vitamin E together also did not show an effect on CRP."

The said study (3 years) would be:

Long-term combined supplementations with alpha-tocopherol and vitamin C have no detectable anti-inflammatory effects in healthy men.

J Nutr. 2003 Apr;133(4):1170-3.

PMID: 12672938

http://tinyurl.com/59fxf

"Antioxidant treatment for 36 mo had no effect on circulating levels of TNF-alpha, IL-6 or CRP."

--

Ken

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Hi Bpinfo:

That is a bit odd. It seems to suggest that the other anti-oxidants

neutralize the benefit of the vitamin C. Very interesting (if true).

Rodney.

> Here is the underlying study:

> http://tinyurl.com/49ztg]

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=pubmed &

> dopt=Abstract & list_uids=15047680

> PMID: 15047680

>

> Subjects were only tested after the two months were over, so the

beneficial

> effect might have occurred at any time up until then. Maybe it even

happens

> immediately.

>

> Also, C + other anti-oxidants together had no effect.

>

>

> OTOH, fish oil did not reduce hr CRP:

> http://snipurl.com/9ao8

> PMID: 15100717

>

> " The median CRP change in the fish oil group did not significantly

differ

> from that in the placebo group... CONCLUSION:: The currently

available data

> -including ours- do not support that beneficial effects on CRP are

involved in a

> mechanism explaining the protective effect on heart disease risk of

n-3 fatty

> acids as present in fish "

>

>

> In a message dated 9/23/04 2:27:06 PM Eastern Daylight Time,

> perspect1111@y... writes:

>

> > " Researchers at the University of California say that

participants

> > who took about 500 milligrams of vitamin C supplements per day

saw a

> > 24 per cent drop in plasma C-reactive protein (CRP) levels after

two

> > months. Recent research suggests that CRP may be a better

predictor

> > of heart disease than cholesterol levels. "

> >

> > http://www.nutraingredients-usa.com/news/news-NG.asp?id=51369

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