Guest guest Posted July 28, 2004 Report Share Posted July 28, 2004 Rodney: it's like pornography; I know it when I see it. That is, an emaciated looking CRONIE. Purely subjective. BUT there are the side effects that don't seem to be correlated with good health. These side effects have been detailed before (loss of libido, anemia, anorexia, osteoporosis, feeling cold, difficult to sit on bony tush, irritability, to name a few). Neither the Okinawans nor the Biospherans seemed to have suffered these side effects (afa we know). If I am incorrect, I'm sure someone will let us know. I have posted several times the portion in Walford's text which states that older mice that were on extreme regimens died YOUNGER than the controls. Pg 50 of " Beyond " middle of page : " ....degree of restriction giving the best results varies with the age with which it is started.......When started (later in life) it actually INCREASED the death rate. Optimal restriction varies with age, and at greater ages should be less severe. See the book for the entire discussion. Of course if more recent research negates this, that would be different. on 7/28/2004 4:12 PM, Rodney at perspect1111@... wrote: > Hi Francesca: > > Some input for you about 'extremism' in CRON, fwiw, not even > requiring a reply (but perhaps it will prompt some thoughts at your > end on this important issue?): > > As you know I am rather new to CR, and while I have learnt a lot in > the last couple of years since I first read BT120YD, I realize I will > be learning a lot more in the next sixty! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 28, 2004 Report Share Posted July 28, 2004 I believe more recent research has identified the problem as being caused by how quickly the older rats were transitioned to severe restriction. Of course it is always problematic trying to translate specific rodent results into useful advice for different, much longer lived animals (like us). We pretty much all agree that the mechanism should work in humans but there's a world of unknown in the details. IMO the more powerful finding from those specific rodent experiments is that yes indeed, rats can do CR wrong. If we wish to accept the good results from rodent research we need to listen to the bad results to. The implication is that you could shorten your life by doing CR wrong! I sure don't know what and where the pitfalls may be. In lieu of more data, moderation just seems prudent. JR -----Original Message----- From: Francesca Skelton [mailto:fskelton@...] Sent: Wednesday, July 28, 2004 3:41 PM support group Subject: Re: [ ] Extremism Rodney: it's like pornography; I know it when I see it. That is, an emaciated looking CRONIE. Purely subjective. BUT there are the side effects that don't seem to be correlated with good health. These side effects have been detailed before (loss of libido, anemia, anorexia, osteoporosis, feeling cold, difficult to sit on bony tush, irritability, to name a few). Neither the Okinawans nor the Biospherans seemed to have suffered these side effects (afa we know). If I am incorrect, I'm sure someone will let us know. I have posted several times the portion in Walford's text which states that older mice that were on extreme regimens died YOUNGER than the controls. Pg 50 of " Beyond " middle of page : " ....degree of restriction giving the best results varies with the age with which it is started.......When started (later in life) it actually INCREASED the death rate. Optimal restriction varies with age, and at greater ages should be less severe. See the book for the entire discussion. Of course if more recent research negates this, that would be different. ________________________________________________________ This email has been scanned by Internet Pathway's Email Gateway scanning system for potentially harmful content, such as viruses or spam. Nothing out of the ordinary was detected in this email. For more information, call 601-776-3355 or email support@... ________________________________________________________ Quote Link to comment Share on other sites More sharing options...
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