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Worse Hepatitis C Disease Linked To Previous Hepatitis B Infection

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DGReview

Worse Hepatitis C Disease Linked To Previous Hepatitis B Infection

A DGReview of : " Previous hepatitis B virus infection is associated with

worse disease stage and occult hepatitis B virus infection has low

prevalence and pathogenicity in hepatitis C virus-positive patients. "

Liver

02/12/2003

By Loshak

Previous hepatitis B virus infection among hepatitis C virus-positive

patients is associated with worse disease stage.

The patients have a low prevalence and pathogenicity of occult hepatitis B

virus infection and there is no difference in distribution between patients

with or without markers of previous hepatitis B virus infection, say

researchers at the University of Genoa, Italy.

Previous hepatitis B virus infection did not seem to be associated with

disease stage or to affect the severity of disease, at least among patients

with chronic hepatitis, they added.

The researchers noted that hepatitis C virus positive patients with chronic

liver disease often showed markers of previous hepatitis B virus infection.

They might also carry occult hepatitis B virus infection.

As those features might influence clinical and biochemical features, as well

as disease stage, the researchers assessed the prevalence and clinical

associations of previous and occult hepatitis B virus infection in 84

patients with chronic hepatitis and 35 patients with liver cirrhosis.

Of these 119 patients, 48 (40.3%) showed markers of previous hepatitis B

virus infection. This was more frequent among patients with cirrhosis (57%)

than with chronic hepatitis (33%).

Chronic hepatitis patients positive for markers of previous hepatitis B

virus infection had worse histology than those negative for such markers.

Eight patients were positive for hepatitis B virus-DNA in serum. There was

no difference in the presence of occult hepatitis B virus infection between

various degrees of liver disease. Likewise, there was no difference in the

presence of occult hepatitis B virus infection between patients who were

positive or negative for markers of previous hepatitis B virus infection.

There were no significant biochemical, virological or histological

differences according to patient age, age at infection, duration of

infection or marker patterns of previous hepatitis B virus,

infection-matched hepatitis B, virus-DNA-positive or virus-DNA-negative

chronic hepatitis patients.

Liver 2003;23:1:12-18. " Previous hepatitis B virus infection is associated

with worse disease stage and occult hepatitis B virus infection has low

prevalence and pathogenicity in hepatitis C virus-positive patients. "

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DGReview

Worse Hepatitis C Disease Linked To Previous Hepatitis B Infection

A DGReview of : " Previous hepatitis B virus infection is associated with

worse disease stage and occult hepatitis B virus infection has low

prevalence and pathogenicity in hepatitis C virus-positive patients. "

Liver

02/12/2003

By Loshak

Previous hepatitis B virus infection among hepatitis C virus-positive

patients is associated with worse disease stage.

The patients have a low prevalence and pathogenicity of occult hepatitis B

virus infection and there is no difference in distribution between patients

with or without markers of previous hepatitis B virus infection, say

researchers at the University of Genoa, Italy.

Previous hepatitis B virus infection did not seem to be associated with

disease stage or to affect the severity of disease, at least among patients

with chronic hepatitis, they added.

The researchers noted that hepatitis C virus positive patients with chronic

liver disease often showed markers of previous hepatitis B virus infection.

They might also carry occult hepatitis B virus infection.

As those features might influence clinical and biochemical features, as well

as disease stage, the researchers assessed the prevalence and clinical

associations of previous and occult hepatitis B virus infection in 84

patients with chronic hepatitis and 35 patients with liver cirrhosis.

Of these 119 patients, 48 (40.3%) showed markers of previous hepatitis B

virus infection. This was more frequent among patients with cirrhosis (57%)

than with chronic hepatitis (33%).

Chronic hepatitis patients positive for markers of previous hepatitis B

virus infection had worse histology than those negative for such markers.

Eight patients were positive for hepatitis B virus-DNA in serum. There was

no difference in the presence of occult hepatitis B virus infection between

various degrees of liver disease. Likewise, there was no difference in the

presence of occult hepatitis B virus infection between patients who were

positive or negative for markers of previous hepatitis B virus infection.

There were no significant biochemical, virological or histological

differences according to patient age, age at infection, duration of

infection or marker patterns of previous hepatitis B virus,

infection-matched hepatitis B, virus-DNA-positive or virus-DNA-negative

chronic hepatitis patients.

Liver 2003;23:1:12-18. " Previous hepatitis B virus infection is associated

with worse disease stage and occult hepatitis B virus infection has low

prevalence and pathogenicity in hepatitis C virus-positive patients. "

Link to comment
Share on other sites

DGReview

Worse Hepatitis C Disease Linked To Previous Hepatitis B Infection

A DGReview of : " Previous hepatitis B virus infection is associated with

worse disease stage and occult hepatitis B virus infection has low

prevalence and pathogenicity in hepatitis C virus-positive patients. "

Liver

02/12/2003

By Loshak

Previous hepatitis B virus infection among hepatitis C virus-positive

patients is associated with worse disease stage.

The patients have a low prevalence and pathogenicity of occult hepatitis B

virus infection and there is no difference in distribution between patients

with or without markers of previous hepatitis B virus infection, say

researchers at the University of Genoa, Italy.

Previous hepatitis B virus infection did not seem to be associated with

disease stage or to affect the severity of disease, at least among patients

with chronic hepatitis, they added.

The researchers noted that hepatitis C virus positive patients with chronic

liver disease often showed markers of previous hepatitis B virus infection.

They might also carry occult hepatitis B virus infection.

As those features might influence clinical and biochemical features, as well

as disease stage, the researchers assessed the prevalence and clinical

associations of previous and occult hepatitis B virus infection in 84

patients with chronic hepatitis and 35 patients with liver cirrhosis.

Of these 119 patients, 48 (40.3%) showed markers of previous hepatitis B

virus infection. This was more frequent among patients with cirrhosis (57%)

than with chronic hepatitis (33%).

Chronic hepatitis patients positive for markers of previous hepatitis B

virus infection had worse histology than those negative for such markers.

Eight patients were positive for hepatitis B virus-DNA in serum. There was

no difference in the presence of occult hepatitis B virus infection between

various degrees of liver disease. Likewise, there was no difference in the

presence of occult hepatitis B virus infection between patients who were

positive or negative for markers of previous hepatitis B virus infection.

There were no significant biochemical, virological or histological

differences according to patient age, age at infection, duration of

infection or marker patterns of previous hepatitis B virus,

infection-matched hepatitis B, virus-DNA-positive or virus-DNA-negative

chronic hepatitis patients.

Liver 2003;23:1:12-18. " Previous hepatitis B virus infection is associated

with worse disease stage and occult hepatitis B virus infection has low

prevalence and pathogenicity in hepatitis C virus-positive patients. "

Link to comment
Share on other sites

DGReview

Worse Hepatitis C Disease Linked To Previous Hepatitis B Infection

A DGReview of : " Previous hepatitis B virus infection is associated with

worse disease stage and occult hepatitis B virus infection has low

prevalence and pathogenicity in hepatitis C virus-positive patients. "

Liver

02/12/2003

By Loshak

Previous hepatitis B virus infection among hepatitis C virus-positive

patients is associated with worse disease stage.

The patients have a low prevalence and pathogenicity of occult hepatitis B

virus infection and there is no difference in distribution between patients

with or without markers of previous hepatitis B virus infection, say

researchers at the University of Genoa, Italy.

Previous hepatitis B virus infection did not seem to be associated with

disease stage or to affect the severity of disease, at least among patients

with chronic hepatitis, they added.

The researchers noted that hepatitis C virus positive patients with chronic

liver disease often showed markers of previous hepatitis B virus infection.

They might also carry occult hepatitis B virus infection.

As those features might influence clinical and biochemical features, as well

as disease stage, the researchers assessed the prevalence and clinical

associations of previous and occult hepatitis B virus infection in 84

patients with chronic hepatitis and 35 patients with liver cirrhosis.

Of these 119 patients, 48 (40.3%) showed markers of previous hepatitis B

virus infection. This was more frequent among patients with cirrhosis (57%)

than with chronic hepatitis (33%).

Chronic hepatitis patients positive for markers of previous hepatitis B

virus infection had worse histology than those negative for such markers.

Eight patients were positive for hepatitis B virus-DNA in serum. There was

no difference in the presence of occult hepatitis B virus infection between

various degrees of liver disease. Likewise, there was no difference in the

presence of occult hepatitis B virus infection between patients who were

positive or negative for markers of previous hepatitis B virus infection.

There were no significant biochemical, virological or histological

differences according to patient age, age at infection, duration of

infection or marker patterns of previous hepatitis B virus,

infection-matched hepatitis B, virus-DNA-positive or virus-DNA-negative

chronic hepatitis patients.

Liver 2003;23:1:12-18. " Previous hepatitis B virus infection is associated

with worse disease stage and occult hepatitis B virus infection has low

prevalence and pathogenicity in hepatitis C virus-positive patients. "

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