Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors

[Guest guest]

Wouldn't supplementing with glutathione help?

Sherry

[Guest guest]

Is there a glutathione supplement?

--- Kathy Ratkiewicz <Kathy_R@...> wrote:

> This study was done on kids who do NOT have Ds..and

> since glutathione is

> already depleted in Ds, it would follow that it

> would not be a good idea to

> give acetaminophen/Tylenol/paracetomal to a child

> w/Ds who has recently

> gotten immunizations.(since the liver uses

> glutathione to metabolize

> acetaminophen, that would decrease glutathione even

> more, and make the child

> more susceptible to damage to the nervous system

> from the thimerosal in the

> vaccine)

>

>

>

> (at least, that is how I am understanding it)

>

>

>

> http://www.icdrc.org/pdf/Neurotoxarticle.pdf

>

>

>

> kathyR

>

>

>

>

>

>

__________________________________________________

[Guest guest]

You can take oral glutathione but everyone claims it is not effective

--gets used up before it can help or something but I think it helps

Evan --makes his BM's less smelly I think. I read on the internet

that others seemed to think it helped them too so . . . Most

recommend skin patches --transdermal.

Priscilla K

--- and Behnke <behnkesw@...> wrote:

> Is there a glutathione supplement?

>

> --- Kathy Ratkiewicz <Kathy_R@...> wrote:

>

> > This study was done on kids who do NOT have Ds..and

> > since glutathione is

> > already depleted in Ds, it would follow that it

> > would not be a good idea to

> > give acetaminophen/Tylenol/paracetomal to a child

> > w/Ds who has recently

> > gotten immunizations.(since the liver uses

> > glutathione to metabolize

> > acetaminophen, that would decrease glutathione even

> > more, and make the child

> > more susceptible to damage to the nervous system

> > from the thimerosal in the

> > vaccine)

> >

> >

> >

> > (at least, that is how I am understanding it)

> >

> >

> >

> > http://www.icdrc.org/pdf/Neurotoxarticle.pdf

> >

> >

> >

> > kathyR

> >

> >

> >

> >

> >

> >

>

>

> __________________________________________________

>

[Guest guest]

Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors http://www..sciencedirect.com/science?_ob=ArticleURL & _udi=B6W81-4DF44GF-2 & _user=10 & _rdoc=1 & _fmt= & _orig=search & _sort=d & _docanchor= & view=c & _searchStrId=999683166 & _rerunOrigin=scholar.google & _acct=C000050221 & _version=1 & _urlVersion=0 & _userid=10 & md5=31725cccfe8c0e3334a0adb1414d280c

AbstractThimerosol is an antiseptic containing

49.5% ethyl mercury that has been used for years as a preservative in

many infant vaccines and in flu vaccines. Environmental methyl mercury

has been shown to be highly neurotoxic, especially to the developing

brain. Because mercury has a high affinity for thiol (sulfhydryl (SH))

groups, the thiol-containing antioxidant, glutathione (GSH), provides

the major intracellular defense against mercury-induced neurotoxicity.

Cultured neuroblastoma cells were found to have lower levels of GSH and

increased sensitivity to thimerosol toxicity compared to glioblastoma

cells that have higher basal levels of intracellular GSH.

Thimerosal-induced cytotoxicity was associated with depletion of

intracellular GSH in both cell lines. Pretreatment with 100 μM glutathione ethyl ester or N-acetylcysteine

(NAC), but not methionine, resulted in a significant increase in

intracellular GSH in both cell types. Further, pretreatment of the

cells with glutathione ethyl ester or NAC prevented cytotoxicity with

exposure to 15 μM Thimerosal. Although Thimerosal has been

recently removed from most children's vaccines, it is still present in

flu vaccines given to pregnant women, the elderly, and to children in

developing countries. The potential protective effect of GSH or NAC

against mercury toxicity warrants further research as possible adjunct

therapy to individuals still receiving Thimerosal-containing

vaccinations.

Keywords: Thimerosal; Neurotoxicity; Glutathione; N-acetylcysteine "Your talent is God’s gift to you. What you do with it is your gift back to God"The human brain should be used for processing, not storage.

[Guest guest]

Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors http://www..sciencedirect.com/science?_ob=ArticleURL & _udi=B6W81-4DF44GF-2 & _user=10 & _rdoc=1 & _fmt= & _orig=search & _sort=d & _docanchor= & view=c & _searchStrId=999683166 & _rerunOrigin=scholar.google & _acct=C000050221 & _version=1 & _urlVersion=0 & _userid=10 & md5=31725cccfe8c0e3334a0adb1414d280c

AbstractThimerosol is an antiseptic containing

49.5% ethyl mercury that has been used for years as a preservative in

many infant vaccines and in flu vaccines. Environmental methyl mercury

has been shown to be highly neurotoxic, especially to the developing

brain. Because mercury has a high affinity for thiol (sulfhydryl (SH))

groups, the thiol-containing antioxidant, glutathione (GSH), provides

the major intracellular defense against mercury-induced neurotoxicity.

Cultured neuroblastoma cells were found to have lower levels of GSH and

increased sensitivity to thimerosol toxicity compared to glioblastoma

cells that have higher basal levels of intracellular GSH.

Thimerosal-induced cytotoxicity was associated with depletion of

intracellular GSH in both cell lines. Pretreatment with 100 μM glutathione ethyl ester or N-acetylcysteine

(NAC), but not methionine, resulted in a significant increase in

intracellular GSH in both cell types. Further, pretreatment of the

cells with glutathione ethyl ester or NAC prevented cytotoxicity with

exposure to 15 μM Thimerosal. Although Thimerosal has been

recently removed from most children's vaccines, it is still present in

flu vaccines given to pregnant women, the elderly, and to children in

developing countries. The potential protective effect of GSH or NAC

against mercury toxicity warrants further research as possible adjunct

therapy to individuals still receiving Thimerosal-containing

vaccinations.

Keywords: Thimerosal; Neurotoxicity; Glutathione; N-acetylcysteine "Your talent is God’s gift to you. What you do with it is your gift back to God"The human brain should be used for processing, not storage.

[Guest guest]

Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors http://www..sciencedirect.com/science?_ob=ArticleURL & _udi=B6W81-4DF44GF-2 & _user=10 & _rdoc=1 & _fmt= & _orig=search & _sort=d & _docanchor= & view=c & _searchStrId=999683166 & _rerunOrigin=scholar.google & _acct=C000050221 & _version=1 & _urlVersion=0 & _userid=10 & md5=31725cccfe8c0e3334a0adb1414d280c

AbstractThimerosol is an antiseptic containing

49.5% ethyl mercury that has been used for years as a preservative in

many infant vaccines and in flu vaccines. Environmental methyl mercury

has been shown to be highly neurotoxic, especially to the developing

brain. Because mercury has a high affinity for thiol (sulfhydryl (SH))

groups, the thiol-containing antioxidant, glutathione (GSH), provides

the major intracellular defense against mercury-induced neurotoxicity.

Cultured neuroblastoma cells were found to have lower levels of GSH and

increased sensitivity to thimerosol toxicity compared to glioblastoma

cells that have higher basal levels of intracellular GSH.

Thimerosal-induced cytotoxicity was associated with depletion of

intracellular GSH in both cell lines. Pretreatment with 100 μM glutathione ethyl ester or N-acetylcysteine

(NAC), but not methionine, resulted in a significant increase in

intracellular GSH in both cell types. Further, pretreatment of the

cells with glutathione ethyl ester or NAC prevented cytotoxicity with

exposure to 15 μM Thimerosal. Although Thimerosal has been

recently removed from most children's vaccines, it is still present in

flu vaccines given to pregnant women, the elderly, and to children in

developing countries. The potential protective effect of GSH or NAC

against mercury toxicity warrants further research as possible adjunct

therapy to individuals still receiving Thimerosal-containing

vaccinations.

Keywords: Thimerosal; Neurotoxicity; Glutathione; N-acetylcysteine "Your talent is God’s gift to you. What you do with it is your gift back to God"The human brain should be used for processing, not storage.

[Guest guest]

Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors http://www..sciencedirect.com/science?_ob=ArticleURL & _udi=B6W81-4DF44GF-2 & _user=10 & _rdoc=1 & _fmt= & _orig=search & _sort=d & _docanchor= & view=c & _searchStrId=999683166 & _rerunOrigin=scholar.google & _acct=C000050221 & _version=1 & _urlVersion=0 & _userid=10 & md5=31725cccfe8c0e3334a0adb1414d280c

AbstractThimerosol is an antiseptic containing

49.5% ethyl mercury that has been used for years as a preservative in

many infant vaccines and in flu vaccines. Environmental methyl mercury

has been shown to be highly neurotoxic, especially to the developing

brain. Because mercury has a high affinity for thiol (sulfhydryl (SH))

groups, the thiol-containing antioxidant, glutathione (GSH), provides

the major intracellular defense against mercury-induced neurotoxicity.

Cultured neuroblastoma cells were found to have lower levels of GSH and

increased sensitivity to thimerosol toxicity compared to glioblastoma

cells that have higher basal levels of intracellular GSH.

Thimerosal-induced cytotoxicity was associated with depletion of

intracellular GSH in both cell lines. Pretreatment with 100 μM glutathione ethyl ester or N-acetylcysteine

(NAC), but not methionine, resulted in a significant increase in

intracellular GSH in both cell types. Further, pretreatment of the

cells with glutathione ethyl ester or NAC prevented cytotoxicity with

exposure to 15 μM Thimerosal. Although Thimerosal has been

recently removed from most children's vaccines, it is still present in

flu vaccines given to pregnant women, the elderly, and to children in

developing countries. The potential protective effect of GSH or NAC

against mercury toxicity warrants further research as possible adjunct

therapy to individuals still receiving Thimerosal-containing

vaccinations.

Keywords: Thimerosal; Neurotoxicity; Glutathione; N-acetylcysteine "Your talent is God’s gift to you. What you do with it is your gift back to God"The human brain should be used for processing, not storage.