Complex regional pain syndrome after hepatitis B vaccine

[Guest guest]

THE JOURNAL OF PEDIATRICS

December 2003 . Volume 143 . Number 6

Clinical and Laboratory observations

Complex regional pain syndrome after hepatitis B vaccine

Wasil A. Jastaniah, MBBS, FRCPC* ,Simon Dobson, MD, FRCPC G. Lugsdin,

MD, MSc, FRCPC ,Ross E. Petty, MD, PhD, FRCPC

Abstract

Complex regional pain syndrome, characterized by pain, autonomic

dysfunction, and decreased range of motion, developed after hepatitis B

vaccination in four grade-6 children since the introduction of the

vaccination program in British Columbia in1992. The reaction may result from

injection trauma or may be secondary to a vaccine constituent.

Publishing and Reprint Information

From the Divisions of Infectious and Immunological Diseases, Rheumatology,

the Department of Pediatrics, University of British Columbia and British

Columbia's Children's Hospital, British Columbia Centre for Disease Control,

Vancouver, British Columbia, Canada

*Reprints not available from the authors. Please address correspondence to

Wasil Jastaniah, MBBS, FRCPC, 1043 West 7th Ave, Vancouver, British

Columbia, Canada V6H 1B2.; Email: wjastan@...

Submitted June 17, 2002.

Revised May 16, 2003.

Accepted on August 22, 2003.

Copyright © 2003 by Mosby, Inc.

doi:10.1067/S0022-3476(03)00536-5

[Guest guest]

THE JOURNAL OF PEDIATRICS

December 2003 . Volume 143 . Number 6

Clinical and Laboratory observations

Complex regional pain syndrome after hepatitis B vaccine

Wasil A. Jastaniah, MBBS, FRCPC* ,Simon Dobson, MD, FRCPC G. Lugsdin,

MD, MSc, FRCPC ,Ross E. Petty, MD, PhD, FRCPC

Abstract

Complex regional pain syndrome, characterized by pain, autonomic

dysfunction, and decreased range of motion, developed after hepatitis B

vaccination in four grade-6 children since the introduction of the

vaccination program in British Columbia in1992. The reaction may result from

injection trauma or may be secondary to a vaccine constituent.

Publishing and Reprint Information

From the Divisions of Infectious and Immunological Diseases, Rheumatology,

the Department of Pediatrics, University of British Columbia and British

Columbia's Children's Hospital, British Columbia Centre for Disease Control,

Vancouver, British Columbia, Canada

*Reprints not available from the authors. Please address correspondence to

Wasil Jastaniah, MBBS, FRCPC, 1043 West 7th Ave, Vancouver, British

Columbia, Canada V6H 1B2.; Email: wjastan@...

Submitted June 17, 2002.

Revised May 16, 2003.

Accepted on August 22, 2003.

Copyright © 2003 by Mosby, Inc.

doi:10.1067/S0022-3476(03)00536-5