Guest guest Posted October 15, 2001 Report Share Posted October 15, 2001 I took sterols once and had an adverse reaction. . ----- Original Message ----- From: Patty <fdp@...> < > Sent: Monday, October 15, 2001 9:40 AM Subject: Re: Sterols and sterolins > More....the only comment here that concerned me was the fact that sterols > seemed to have the effect of raising levels of cytokines. Dr. Kolb has > stated, I believe, that many implant victims already have too high levels of > cytokines, and increasing them further is not such a good thing.... > > Dr. Kolb? Is this correct? What is your opinion of sterols? > Patty > > Beta-sitosterol and beta-sitosterol glucoside stimulate human peripheral > blood lymphocyte proliferation: Implications for their use as an > immunomodulatory vitamin combination. > Bouic PJD, Etsebeth S, Liebenberg RW, et al. > Int J Immunopharmacol 1996;18:693-700. > > This study reports on a series of in vivo and in vitro studies which clearly > demonstrate that the plant sterols and sterolins (B-Sitosterol and its > Glucoside, B-Sitosterolin) have immunomodulatory properties. The first > experiment performed in vitro demonstrated that sterols and sterolins had a > significant proliferative effect on human T-cells. The effect was observed > in extremely low concentrations of sterol/sterolins on the order of 1 > femtogram which represents only 150 molecules of sterol and 10 molecules of > sterolin. The best response was obtained when a 100:1 sterol/sterolin > mixture was given. The same study was repeated on a small number of human > subjects (8) indicating a T-cell proliferative response from 20% to 920% > after 4 weeks on the sterol/sterolin mixture. No increase was observed for > the 2 subjects receiving placebos. The peak activity of the sterol/sterolin > mixture occurred at 6 hours in the in vitro experiments, indicating an > effect in the initial stages of T-cell proliferation and activation of > membrane antigens. Another in vitro experiment showed significant increases > in the cytokines (immune communication molecules) interleukin-2 and > gamma-interferon on the order between 17% and 41%. Another in vitro > experiment showed an increase in Natural Killer Cell activity for the lysis > of experimental cancer cells with the sterol/sterolin mixture. Although > sterols and sterolins are poorly absorbed and are not synthesized in the > human body, daily intake is required to maintain an optimal immune response. > These experiments prove that a 100:1 sterol/sterolin mixture is a potent > immunomodulator with important implications for the treatment and > restoration of immune dysfunctions. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2001 Report Share Posted October 15, 2001 , I have not looked into Sterols before, but found that they are basically plant fats. I did see a caution for those with Multiple Sclerosis about taking them. Here is one abstract I found. I don't know how expensive they are and if they would be worth taking, but I am sure that it wouldn't hurt to try, if the person did not have MS or MS like symptoms. Anti-inflammatory and antipyretic activities of B-sitosterol Gupta MB, Nath R, Srivastava N, et al. Planta Medica 1980;39:157-163. A basic research study using animal experiments was performed to determine whether sterols (plant fats) had any therapeutic properties such as reducing inflammation (anti-inflammatory), reducing fever (anti-pyretic) and reducing pain (analgesic). An extract of sterols from the seeds of the Indian herbal plant- Cyperus rotundus was used in three separate experiments with rats to determine the medicinal properties. It was demonstrated that sterols possess potent anti-inflammatory properties similar to cortisone. Sterols were also demonstrated to reduce experimentally produced edema. Sterols were also shown to have fever-reducing properties similar to aspirin (ASA). However, the sterols did not possess any pain-reducing or analgesic properties. In separate toxicology tests, sterols were shown to possess a very large margin of safety and produced minimal side effects such as gastric ulceration. The study concluded that sterols possess highly potent anti-inflammatory and anti-pyretic actions with a high margin of safety suggesting its application to human medicine. ----- Original Message ----- From: <cjheer@...> < > Sent: Friday, October 12, 2001 7:03 AM Subject: Sterols and sterolins > I found a really fantastic health and nutrition store in town here > and was thrilled with the product they carried and the knowledgable > staff there. I recieved a copy of there newspaper and magazine and it > was very informative. I talked allot about the use of steroids and > chemo drugs in RA and how these drugs can over the long haul > completely wipe out your immune system leaving you sicker than the > disease itself, it also talked about a woman with severe RA who after > 10 years of killing her immune system with prednisone went off the > med and started taking sterols and sterolins and has now turned a > major corner with her health. Patty are you aware of exactly what > these are and how they work. I am very interested in them and am > going to look into it further, but it sounds promising in treatment > of autoimmune disease such as RA lupus and others that right now are > mostly being treated with toxic drugs. > > I am taking the plaquenil because it seems to be the lesser of all > evils when it comes to autoimmune disease meds, so I am giving it a > shot, but I will not take it for more than a year. I will see, and in > the mean time I will continue with my colostrum and other immune > building supplements as well. > > Well I hope everyone here is doing well. > > God bless, > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2001 Report Share Posted October 15, 2001 More....the only comment here that concerned me was the fact that sterols seemed to have the effect of raising levels of cytokines. Dr. Kolb has stated, I believe, that many implant victims already have too high levels of cytokines, and increasing them further is not such a good thing.... Dr. Kolb? Is this correct? What is your opinion of sterols? Patty Beta-sitosterol and beta-sitosterol glucoside stimulate human peripheral blood lymphocyte proliferation: Implications for their use as an immunomodulatory vitamin combination. Bouic PJD, Etsebeth S, Liebenberg RW, et al. Int J Immunopharmacol 1996;18:693-700. This study reports on a series of in vivo and in vitro studies which clearly demonstrate that the plant sterols and sterolins (B-Sitosterol and its Glucoside, B-Sitosterolin) have immunomodulatory properties. The first experiment performed in vitro demonstrated that sterols and sterolins had a significant proliferative effect on human T-cells. The effect was observed in extremely low concentrations of sterol/sterolins on the order of 1 femtogram which represents only 150 molecules of sterol and 10 molecules of sterolin. The best response was obtained when a 100:1 sterol/sterolin mixture was given. The same study was repeated on a small number of human subjects (8) indicating a T-cell proliferative response from 20% to 920% after 4 weeks on the sterol/sterolin mixture. No increase was observed for the 2 subjects receiving placebos. The peak activity of the sterol/sterolin mixture occurred at 6 hours in the in vitro experiments, indicating an effect in the initial stages of T-cell proliferation and activation of membrane antigens. Another in vitro experiment showed significant increases in the cytokines (immune communication molecules) interleukin-2 and gamma-interferon on the order between 17% and 41%. Another in vitro experiment showed an increase in Natural Killer Cell activity for the lysis of experimental cancer cells with the sterol/sterolin mixture. Although sterols and sterolins are poorly absorbed and are not synthesized in the human body, daily intake is required to maintain an optimal immune response. These experiments prove that a 100:1 sterol/sterolin mixture is a potent immunomodulator with important implications for the treatment and restoration of immune dysfunctions. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2001 Report Share Posted October 15, 2001 The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners: Inhibition of post marathon immune suppression and inflammation Bouic PJD, van Jaarsveld PP, A, et al. Int J Sports Med 1999;20:258-262. A double blind study was performed on marathon runners to see if the addition of a sterol/sterolin mixture would prevent the characteristic immune suppression and inflammatory reaction characteristic to high intensity athletics. Twenty marathon runners were recruited to take part in the trial and blood draws and medical histories were taken 4 weeks prior to the marathon event and three days after. Half the group received a placebo and the other half received a 100:1 mixture of sterol/sterolins. The RBC count went down significantly for the placebo group but remained the same for the sterol treatment group. Neutrophils rose significantly for the treatment group indicating infection but remained constant in the treatment group. The lymphocyte count went down for the placebo group, specifically the CD3, C04, and CD8 subsets. The treatment group actually experienced a significant rise for the CD3 and CD4 lymphocyte subsets. Interleukin 6 levels, which indicate an inflammatory reaction went up for the placebo group, but down in the treatment group. As well, the cortisol levels, which indicate stress levels and degree of immunosuppression were significantly elevated for the placebo group, but remained constant in the treatment group. The treatment group showed an increase in DHEA levels and a decrease in the Cortisol:DHEA ratio, indicating that the sterol/sterolin mixture was helping to buffer the negative side effects of the stress response. The results of this experiment clearly show that taking a sterol/sterolin mixture prior to a highly stressful physical event protected the treatment group from immuno-suppression typically exhibited by the placebo group. As well the sterol/sterolin mixture protected against an excessive inflammatory response typical of anyone running a marathon. Thirdly, the sterol/sterolin mixture buffered the excessive release on cortisol with its immunosuppressive effects. As well the sterol/sterolin mixture raised OHEA levels and lowered the Cortisol:DHEA ratio indicating a more adaptive response to stress. These results indicate that sterol/sterolins are adaptogenic in that they modulate the immune and stress response. This makes them extremely valuable adjuncts to the prevention and treatment of a wide range of stress-mediated disorders, as well as immune dysregulation and inflammatory diseases. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2004 Report Share Posted September 12, 2004 We got Moducare through Mike's homeopath-it wsa wonderful [ ] sterols and sterolins > > Has anyone ever tried these to help balance Th1 and Th2? > > TIA > a > mom to > > > > > ======================================================= > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2004 Report Share Posted September 12, 2004 Hi, How long are you supposed to stay on Moducare? > We got Moducare through Mike's homeopath-it wsa wonderful > [ ] sterols and sterolins > > > > > > Has anyone ever tried these to help balance Th1 and Th2? > > > > TIA > > a > > mom to > > > > > > > > > > ======================================================= > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2004 Report Share Posted September 12, 2004 no idea. Mike was on it for quite a while-maybe 6 months. [ ] sterols and sterolins > > > > > > > > > > Has anyone ever tried these to help balance Th1 and Th2? > > > > > > TIA > > > a > > > mom to > > > > > > > > > > > > > > > ======================================================= > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2004 Report Share Posted September 12, 2004 HI a He still has both. Moducare helped his immune system recover form an improperly administered homeopathic remedy. We used it, along with immunolin, to clear up an infection while calming an inflammation. Mike will probably have some food/med intolerances for life, however, they are much better than they have been in the past. HIs diet is largely improved-he can tolerate foods from all of the food groups, just not as wide a variety as we would all like. Moducare still helps when the environmental allergies get out of control. [ ] sterols and sterolins > > > > > > > > > > > > > > > > > > Has anyone ever tried these to help balance Th1 and Th2? > > > > > > > > > > TIA > > > > > a > > > > > mom to > > > > > > ======================================================= > Quote Link to comment Share on other sites More sharing options...
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