Hepatitis B: overview of the burden of disease in the Asia-Pacific region

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Hepatitis B: overview of the burden of disease in the Asia-Pacific region

Authors: Lesmana, tius A.1; Leung, Wai-Yee2; Mahachai, Varocha3;

Phiet, Pham Hoang4; Suh, Dong Jin5; Yao, Guangbi6; Zhuang, H.7

Source: Liver International, Volume 26, Supplement 2, December 2006, pp.

3-10(8)

Publisher: Blackwell Publishing

Lesmana LA, Leung NWY, Mahachai V, Phiet PH, Suh DJ, Yao GB, Zhuang H.

Hepatitis B: overview of the burden of disease in the Asia-Pacific region.

Liver International 2006: 26: 3-10.

Abstract:

Hepatitis B virus (HBV) infection and its liver-related complications are a

substantial health concern in the Asia-Pacific region. Over the last two

decades, public health interventions and the implementation of universal

vaccination programs have substantially reduced the incidence of HBV

infections in many countries in this region. However, large proportions of

individuals remain chronically infected and subject to an increased risk for

serious sequelae, including cirrhosis, decompensated liver disease, and

hepatocellular carcinoma. The management of HBV infection varies throughout

the Asia-Pacific region, with each country confronting different issues

related to prevention, screening, and treatment. These issues include the

availability of diagnostic testing and treatment, the cost of diagnosis and

treatment, the availability of trained medical professionals and medical

facilities, and disease awareness among primary care physicians and the

public. This article reviews the epidemiology of HBV infection in the

Asia-Pacific region, explains factors influencing hepatitis B prevalence and

prevention, and discusses barriers to prevention and treatment of chronic

hepatitis B and its liver-related complications.

Keywords: Asia-Pacific; epidemiology; hepatitis B; prevalence; prevention

Document Type: Research article

DOI: 10.1111/j.1478-3231.2006.01370.x

Affiliations: 1: University of Indonesia, Jakarta, Indonesia, 2: Alice Ho

Miu Ling Nethersole Hospital, Hong Kong Sar, China, 3: Chulalongkorn

University, Bangkok, Thailand, 4: University of Medicine and Pharmacy, Ho

Chi Minh City, Vietnam, 5: Asan Medical Center, University of Ulsan, Seoul,

South Korea, 6: Shanghai Jing-An Qu Central Hospital, Shanghai, China, 7:

Peking University Health Science Center, Beijing, China

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[Guest guest]

Hepatitis B: overview of the burden of disease in the Asia-Pacific region

Authors: Lesmana, tius A.1; Leung, Wai-Yee2; Mahachai, Varocha3;

Phiet, Pham Hoang4; Suh, Dong Jin5; Yao, Guangbi6; Zhuang, H.7

Source: Liver International, Volume 26, Supplement 2, December 2006, pp.

3-10(8)

Publisher: Blackwell Publishing

Lesmana LA, Leung NWY, Mahachai V, Phiet PH, Suh DJ, Yao GB, Zhuang H.

Hepatitis B: overview of the burden of disease in the Asia-Pacific region.

Liver International 2006: 26: 3-10.

Abstract:

Hepatitis B virus (HBV) infection and its liver-related complications are a

substantial health concern in the Asia-Pacific region. Over the last two

decades, public health interventions and the implementation of universal

vaccination programs have substantially reduced the incidence of HBV

infections in many countries in this region. However, large proportions of

individuals remain chronically infected and subject to an increased risk for

serious sequelae, including cirrhosis, decompensated liver disease, and

hepatocellular carcinoma. The management of HBV infection varies throughout

the Asia-Pacific region, with each country confronting different issues

related to prevention, screening, and treatment. These issues include the

availability of diagnostic testing and treatment, the cost of diagnosis and

treatment, the availability of trained medical professionals and medical

facilities, and disease awareness among primary care physicians and the

public. This article reviews the epidemiology of HBV infection in the

Asia-Pacific region, explains factors influencing hepatitis B prevalence and

prevention, and discusses barriers to prevention and treatment of chronic

hepatitis B and its liver-related complications.

Keywords: Asia-Pacific; epidemiology; hepatitis B; prevalence; prevention

Document Type: Research article

DOI: 10.1111/j.1478-3231.2006.01370.x

Affiliations: 1: University of Indonesia, Jakarta, Indonesia, 2: Alice Ho

Miu Ling Nethersole Hospital, Hong Kong Sar, China, 3: Chulalongkorn

University, Bangkok, Thailand, 4: University of Medicine and Pharmacy, Ho

Chi Minh City, Vietnam, 5: Asan Medical Center, University of Ulsan, Seoul,

South Korea, 6: Shanghai Jing-An Qu Central Hospital, Shanghai, China, 7:

Peking University Health Science Center, Beijing, China

http://www.ingentaconnect.com/content/mksg/liv/2006/00000026/A00201s2/art00002;j\

sessionid=6htdeck49a8de.henrietta

_________________________________________________________________

View Athlete’s Collections with Live Search

http://sportmaps.live.com/index.html?source=hmemailtaglinenov06 & FORM=MGAC01