Re: A primer on the molecular virology of hcv

[Guest guest]

That was great, Alley. More straight forward and understandable than most of

the abstracts or articles I've read, and I'm a biologist.........of sorts....at

least that's what I was trained to be.

Merry Christmas,

Anne

A primer on the molecular virology of hcv

>

> http://www.gastrohep.com/reviews/review.asp?id=943

> A primer on the molecular virology of hepatitis C.

> Moradpour D, Blum HE

> Liver Int. 2004 2004; 24(6): 519-25

> Download the full article (PDF) ( Help me)

>

> Abstract

> Exciting advances have recently been made in the understanding of the

molecular virology of hepatitis C. Powerful model systems have been developed

that allow to systematically dissect important steps of the hepatitis C virus

(HCV) life cycle. These include new systems for functional analyses of the HCV

glycoproteins, providing insights into possible HCV receptors and cell entry

mechanisms, and the replicon system, which has revolutionized investigation of

HCV RNA replication and has facilitated drug discovery efforts. The largest gaps

remain in the understanding of the virion structure and the processes that lead

to the assembly, packaging and release of virions. However, given the pace of

current HCV research, progress in these directions may be expected in the near

future. Here, we provide a primer on the molecular virology of hepatitis C, with

particular reference to novel antiviral targets and therapeutic strategies.

>

>

>

>

[Guest guest]

That was great, Alley. More straight forward and understandable than most of

the abstracts or articles I've read, and I'm a biologist.........of sorts....at

least that's what I was trained to be.

Merry Christmas,

Anne

A primer on the molecular virology of hcv

>

> http://www.gastrohep.com/reviews/review.asp?id=943

> A primer on the molecular virology of hepatitis C.

> Moradpour D, Blum HE

> Liver Int. 2004 2004; 24(6): 519-25

> Download the full article (PDF) ( Help me)

>

> Abstract

> Exciting advances have recently been made in the understanding of the

molecular virology of hepatitis C. Powerful model systems have been developed

that allow to systematically dissect important steps of the hepatitis C virus

(HCV) life cycle. These include new systems for functional analyses of the HCV

glycoproteins, providing insights into possible HCV receptors and cell entry

mechanisms, and the replicon system, which has revolutionized investigation of

HCV RNA replication and has facilitated drug discovery efforts. The largest gaps

remain in the understanding of the virion structure and the processes that lead

to the assembly, packaging and release of virions. However, given the pace of

current HCV research, progress in these directions may be expected in the near

future. Here, we provide a primer on the molecular virology of hepatitis C, with

particular reference to novel antiviral targets and therapeutic strategies.

>

>

>

>