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Bio-Technology General Corp. Announces Initial Hepatitis-B Vaccine

Monday February 14 9:48am

Source: BusinessWire

ISELIN, N.J.--(BUSINESS WIRE)--February 14, 2000--Bio-Technology General

Corp. (NASDAQ:BTGC) today announced that it has received approval to market

its genetically engineered hepatitis B vaccine, Bio-Hep-B, from the

Israel Ministry of Health. This product, the first recombinant hepatitis B

vaccine to be approved anywhere in the world that integrates the S, pre-S1,

and pre-S2 surface proteins of the virus, enables successful immunization

with significantly lower doses of vaccine than other recombinant hepatitis B

vaccines. Bio-Hep-B represents the most advanced hepatitis B vaccine in

terms of its efficacy profile.

BTG's Bio-Hep-B has been tested in a broad-based clinical research program

in several thousand individuals, including adults, children, neonates,

individuals at high-risk for infection, immunosuppressed individuals, and

non-responders to other hepatitis B vaccines. In all of BTG's studies,

Bio-Hep-B elicited a quicker response and higher levels of circulating

antibodies to the hepatitis B virus than other recombinant hepatitis B

vaccines. This suggests the potential, when utilizing Bio-Hep-B, for faster

and better protection against the virus.

" We are enormously pleased to have received our first approval for

Bio-Hep-B, " stated Sim Fass, Chairman and CEO of Bio-Technology General,

" and we intend to launch it in Israel at the earliest opportunity. Of much

greater commercial significance, however, is that the Israeli approval,

together with a Certificate of Free Sale, allows us and our licensees, Swiss

Serum, SciGen, and Afrovax to initiate the registration process for

Bio-Hep-B in many countries around the world. In addition, in some

territories, the Israeli approval and Certificate of Free Sale are

themselves sufficient for us to offer Bio-Hep-B for sale immediately. We

believe Bio-Hep-B will have wide appeal in many countries where hepatitis B

is endemic. We expect it to prove to be a superior alternative to both

plasma derived vaccines and recombinant vaccines, such as Recombivax HB®

and Engerix-B®, which incorporate only the S antigen. We intend, together

with our partners, to actively compete in the $1 billion worldwide market

for hepatitis B vaccines. "

Bio-Technology General Corp., a leading biopharmaceutical company, develops,

manufactures and markets genetically engineered and other products for human

health care. The Company's products are marketed in over thirty countries

worldwide.

Statements in this news release concerning the Company's business outlook or

future economic performance, anticipated profitability, revenues, expenses

or other financial items; and statements concerning assumptions made or

expectations as to any future events, conditions, performance or other

matters, are " forward-looking statements " as that term is defined under the

Federal Securities Laws. Forward-looking statements are subject to risks,

uncertainties and other factors which could cause actual results to differ

materially from those stated in such statements. Such risks, uncertainties

and factors include, but are not limited to, changes and delays in product

development plans and schedules, customer acceptance of new products,

changes in pricing or other actions by competitors, patents owned by the

Company and its competitors, and general economic conditions, as well as

other risks detailed in the Company's filings with the Securities and

Exchange Commission.

Contact: Bio-Technology General Corp.

Leah Berkovits

732-632-8800

or

Investor Relations

Wolfe Axelrod Weinberger Associates

Don Weinberger

212-370-4500

----------------------

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Bio-Technology General Corp. Announces Initial Hepatitis-B Vaccine

Monday February 14 9:48am

Source: BusinessWire

ISELIN, N.J.--(BUSINESS WIRE)--February 14, 2000--Bio-Technology General

Corp. (NASDAQ:BTGC) today announced that it has received approval to market

its genetically engineered hepatitis B vaccine, Bio-Hep-B, from the

Israel Ministry of Health. This product, the first recombinant hepatitis B

vaccine to be approved anywhere in the world that integrates the S, pre-S1,

and pre-S2 surface proteins of the virus, enables successful immunization

with significantly lower doses of vaccine than other recombinant hepatitis B

vaccines. Bio-Hep-B represents the most advanced hepatitis B vaccine in

terms of its efficacy profile.

BTG's Bio-Hep-B has been tested in a broad-based clinical research program

in several thousand individuals, including adults, children, neonates,

individuals at high-risk for infection, immunosuppressed individuals, and

non-responders to other hepatitis B vaccines. In all of BTG's studies,

Bio-Hep-B elicited a quicker response and higher levels of circulating

antibodies to the hepatitis B virus than other recombinant hepatitis B

vaccines. This suggests the potential, when utilizing Bio-Hep-B, for faster

and better protection against the virus.

" We are enormously pleased to have received our first approval for

Bio-Hep-B, " stated Sim Fass, Chairman and CEO of Bio-Technology General,

" and we intend to launch it in Israel at the earliest opportunity. Of much

greater commercial significance, however, is that the Israeli approval,

together with a Certificate of Free Sale, allows us and our licensees, Swiss

Serum, SciGen, and Afrovax to initiate the registration process for

Bio-Hep-B in many countries around the world. In addition, in some

territories, the Israeli approval and Certificate of Free Sale are

themselves sufficient for us to offer Bio-Hep-B for sale immediately. We

believe Bio-Hep-B will have wide appeal in many countries where hepatitis B

is endemic. We expect it to prove to be a superior alternative to both

plasma derived vaccines and recombinant vaccines, such as Recombivax HB®

and Engerix-B®, which incorporate only the S antigen. We intend, together

with our partners, to actively compete in the $1 billion worldwide market

for hepatitis B vaccines. "

Bio-Technology General Corp., a leading biopharmaceutical company, develops,

manufactures and markets genetically engineered and other products for human

health care. The Company's products are marketed in over thirty countries

worldwide.

Statements in this news release concerning the Company's business outlook or

future economic performance, anticipated profitability, revenues, expenses

or other financial items; and statements concerning assumptions made or

expectations as to any future events, conditions, performance or other

matters, are " forward-looking statements " as that term is defined under the

Federal Securities Laws. Forward-looking statements are subject to risks,

uncertainties and other factors which could cause actual results to differ

materially from those stated in such statements. Such risks, uncertainties

and factors include, but are not limited to, changes and delays in product

development plans and schedules, customer acceptance of new products,

changes in pricing or other actions by competitors, patents owned by the

Company and its competitors, and general economic conditions, as well as

other risks detailed in the Company's filings with the Securities and

Exchange Commission.

Contact: Bio-Technology General Corp.

Leah Berkovits

732-632-8800

or

Investor Relations

Wolfe Axelrod Weinberger Associates

Don Weinberger

212-370-4500

----------------------

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  • 6 years later...
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Due to the trouble I have had with spam, I request that any group message that might include myself, please send the copy to me as a blind copy (BCC) so the multitude of others may not see my e-mail address. I might also suggest that all recipients be send as BCC. If for some reason, you cannot send to me as BCC, please delete my name and address from your distribution list. Thanks for you understanding.KG6EE <kg6ee@...> wrote: Iran: Jews, Christians Must Wear Badges In a move reminiscent of the Nazis forcing Jews to wear a Star of insignia, Iran’s

parliament has reportedly passed a law requiring Jews, Christians and other religious minorities to wear color-coded badges to identify them as non-Muslims. The law would also set a dress code for all Iranians, requiring them to wear "standard Islamic garments.” The law, which must be approved by Iran's "Supreme Leader" Ali Khamenei before taking effect, requires Iran's roughly 25,000 Jews to sew a yellow strip of cloth on the front of their clothes. Christians would be forced to wear red badges and Zoroastrians would wear blue cloth, according to Canada’s National Post. "This is reminiscent of the Holocaust," said Rabbi Marvin Hier, dean of the Simon Wiesenthal Center in Los Angeles. . . .http://www.newsmax.com/archives/ic/2006/5/19/155943.shtml?s=ic?s=im

How low will we go? Check out Messenger’s low PC-to-Phone call rates.

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here here i agree with bill this group is a groups for support and to listen to those familyas and or pataints that have defibrilaot pacemakers or any letaed heart issues and health this is not the right place to send infomation like the ran law thing this group is a important part of peoples lifes we are here to listen to each other and to worryes conceres and just be a shoulder howere this groups is limited to medical related issuses in which the subject talked on it should be keep to the issues guidline inless other related in for of medicaly or support ! so yes bill i agree whole haertedly with you i think whoever needs support is welcome but just to spam on her jon did not work this hard for the group to me used like that ! stacie,22 shocking life for shocking people !billmahan <billandmarthamahan@...>

wrote: INFO: Iran: Jews, Christians Must Wear Badges My maternal parents

emigrated to the US from Hungary a little more than a hundred years ago, leaving behind their families, mostly in BudaPest. Hitler's holocaust took the lives of somewhere between nine and thirteen members of their (my) families, Jewish on her side, Catholic on his. I take the Holocaust and genocide and government-sponsored oppression very seriously. But this is definitely--absolutely--positively--not the forum on which to discus or even bring up the subject. We are all here for a once semi-unique medical device we had implanted in our chests to keep us alive. Our mutual concerns and reason for being on this forum are medical and the support we give one another in that regard. No matter how important in this world some other issue might be, this forum is

not where the subject belongs. The only political questions and issues appropriate for the are those that directly affect us medically because of our defibrillators or the accompanying medical conditions, treatment or other activities. Please respect the purpose and integrity of this forum and not post political material, no matter how important it might be to you or anyone else, even if it is just informational only. Mr. Duffy did not create and maintain the for any individual to use it as a vehicle for their own political views unrelated to implanted defibrillators and how those of us who have them are coping. I also noted right away that you chose not to sign your posting or otherwise identify yourself beyond the anonymity of your e-mail address. Thank you. Bill Mahan

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Sorry i did not respond immediately, i have been very busy with work. I agree with Bill and Stacie. As the moderator of this group, I would appreciate if you refrain from political and religious discussions. Thank you!... TURKLIghtingpaw <lightingpaw@...> wrote: here here i agree with bill this group is a groups for support and to listen to those familyas and or pataints that have defibrilaot pacemakers or any letaed heart issues and health this is not the right place to send infomation like the ran law thing this group is a important part of peoples lifes we are here to listen to each other and to worryes conceres and just be a shoulder howere this groups is limited to medical related issuses in which the subject talked on it should be keep to the issues guidline inless other

related in for of medicaly or support ! so yes bill i agree whole haertedly with you i think whoever needs support is welcome but just to spam on her jon did not work this hard for the group to me used like that ! stacie,22 shocking life for shocking people !billmahan <billandmarthamahan@...> wrote: INFO: Iran: Jews, Christians Must Wear Badges My maternal parents emigrated to the US from Hungary a little more than a hundred years ago, leaving behind their families, mostly in BudaPest. Hitler's holocaust took the lives of somewhere between nine and thirteen members of their (my) families, Jewish

on her side, Catholic on his. I take the Holocaust and genocide and government-sponsored oppression very seriously. But this is definitely--absolutely--positively--not the forum on which to discus or even bring up the subject. We are all here for a once semi-unique medical device we had implanted in our chests to keep us alive. Our mutual concerns and reason for being on this forum are medical and the support we give one another in that regard. No matter how important in this world some other issue might be, this forum is not where the subject belongs. The only political questions and issues appropriate for the are those that directly affect us medically because of our defibrillators or the accompanying medical conditions,

treatment or other activities. Please respect the purpose and integrity of this forum and not post political material, no matter how important it might be to you or anyone else, even if it is just informational only. Mr. Duffy did not create and maintain the for any individual to use it as a vehicle for their own political views unrelated to implanted defibrillators and how those of us who have them are coping. I also noted right away that you chose not to sign your posting or otherwise identify yourself beyond the anonymity of your e-mail address. Thank you. Bill Mahan

Sneak preview the all-new .com. It's not radically different. Just radically better.

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Sorry i did not respond immediately, i have been very busy with work. I agree with Bill and Stacie. As the moderator of this group, I would appreciate if you refrain from political and religious discussions. Thank you!... TURKLIghtingpaw <lightingpaw@...> wrote: here here i agree with bill this group is a groups for support and to listen to those familyas and or pataints that have defibrilaot pacemakers or any letaed heart issues and health this is not the right place to send infomation like the ran law thing this group is a important part of peoples lifes we are here to listen to each other and to worryes conceres and just be a shoulder howere this groups is limited to medical related issuses in which the subject talked on it should be keep to the issues guidline inless other

related in for of medicaly or support ! so yes bill i agree whole haertedly with you i think whoever needs support is welcome but just to spam on her jon did not work this hard for the group to me used like that ! stacie,22 shocking life for shocking people !billmahan <billandmarthamahan@...> wrote: INFO: Iran: Jews, Christians Must Wear Badges My maternal parents emigrated to the US from Hungary a little more than a hundred years ago, leaving behind their families, mostly in BudaPest. Hitler's holocaust took the lives of somewhere between nine and thirteen members of their (my) families, Jewish

on her side, Catholic on his. I take the Holocaust and genocide and government-sponsored oppression very seriously. But this is definitely--absolutely--positively--not the forum on which to discus or even bring up the subject. We are all here for a once semi-unique medical device we had implanted in our chests to keep us alive. Our mutual concerns and reason for being on this forum are medical and the support we give one another in that regard. No matter how important in this world some other issue might be, this forum is not where the subject belongs. The only political questions and issues appropriate for the are those that directly affect us medically because of our defibrillators or the accompanying medical conditions,

treatment or other activities. Please respect the purpose and integrity of this forum and not post political material, no matter how important it might be to you or anyone else, even if it is just informational only. Mr. Duffy did not create and maintain the for any individual to use it as a vehicle for their own political views unrelated to implanted defibrillators and how those of us who have them are coping. I also noted right away that you chose not to sign your posting or otherwise identify yourself beyond the anonymity of your e-mail address. Thank you. Bill Mahan

Sneak preview the all-new .com. It's not radically different. Just radically better.

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i'm sorry i did not talk political ! i was responed to what soemone easle had sent all i ment was that this wasnt the right place to seend it but i am sorry i didnot think it would hurt to tell thim this was the wrong place ! TURK <goturk1@...> wrote: Sorry i did not respond immediately, i have been very busy with work. I agree with Bill and Stacie. As the moderator of this group, I would appreciate if you refrain from political and religious discussions. Thank you!... TURKLIghtingpaw <lightingpaw@...> wrote: here here i agree with bill this group is a groups for support and to listen to those familyas and or pataints that have defibrilaot

pacemakers or any letaed heart issues and health this is not the right place to send infomation like the ran law thing this group is a important part of peoples lifes we are here to listen to each other and to worryes conceres and just be a shoulder howere this groups is limited to medical related issuses in which the subject talked on it should be keep to the issues guidline inless other related in for of medicaly or support ! so yes bill i agree whole haertedly with you i think whoever needs support is welcome but just to spam on her jon did not work this hard for the group to me used like that ! stacie,22 shocking life for shocking people !billmahan <billandmarthamahan@...> wrote: INFO: Iran: Jews, Christians Must Wear Badges My

maternal parents emigrated to the US from Hungary a little more than a hundred years ago, leaving behind their families, mostly in BudaPest. Hitler's holocaust took the lives of somewhere between nine and thirteen members of their (my) families, Jewish on her side, Catholic on his. I take the Holocaust and genocide and government-sponsored oppression very seriously. But this is definitely--absolutely--positively--not the forum on which to discus or even bring up the subject. We are all here for a once semi-unique medical device we had implanted in our chests to keep us alive. Our mutual concerns and reason for being on this forum are medical and the support we give one another in that regard. No matter how important in this world some other issue might

be, this forum is not where the subject belongs. The only political questions and issues appropriate for the are those that directly affect us medically because of our defibrillators or the accompanying medical conditions, treatment or other activities. Please respect the purpose and integrity of this forum and not post political material, no matter how important it might be to you or anyone else, even if it is just informational only. Mr. Duffy did not create and maintain the for any individual to use it as a vehicle for their own political views unrelated to implanted defibrillators and how those of us who have them are coping. I also noted right away that you chose not to sign your posting or otherwise identify yourself beyond the anonymity of your e-mail address. Thank you. Bill Mahan Sneak preview the all-new .com. It's not radically different. Just radically better.

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ooooooooops sorry did not read the email correctly sorry turk ! though you ment something easle ! TURK <goturk1@...> wrote: Sorry i did not respond immediately, i have been very busy with work. I agree with Bill and Stacie. As the moderator of this group, I would appreciate if you refrain from political and religious discussions. Thank you!... TURKLIghtingpaw <lightingpaw@...> wrote: here here i agree with bill this group is a groups for support and to listen to those familyas and or pataints that have defibrilaot pacemakers or any letaed heart issues and health this is not the right place to send infomation like the ran law thing

this group is a important part of peoples lifes we are here to listen to each other and to worryes conceres and just be a shoulder howere this groups is limited to medical related issuses in which the subject talked on it should be keep to the issues guidline inless other related in for of medicaly or support ! so yes bill i agree whole haertedly with you i think whoever needs support is welcome but just to spam on her jon did not work this hard for the group to me used like that ! stacie,22 shocking life for shocking people !billmahan <billandmarthamahan@...> wrote: INFO: Iran: Jews, Christians Must Wear Badges My maternal parents emigrated to the US from Hungary a little more than a hundred years ago, leaving behind their families, mostly in

BudaPest. Hitler's holocaust took the lives of somewhere between nine and thirteen members of their (my) families, Jewish on her side, Catholic on his. I take the Holocaust and genocide and government-sponsored oppression very seriously. But this is definitely--absolutely--positively--not the forum on which to discus or even bring up the subject. We are all here for a once semi-unique medical device we had implanted in our chests to keep us alive. Our mutual concerns and reason for being on this forum are medical and the support we give one another in that regard. No matter how important in this world some other issue might be, this forum is not where the subject belongs. The only political questions and issues appropriate for the are those

that directly affect us medically because of our defibrillators or the accompanying medical conditions, treatment or other activities. Please respect the purpose and integrity of this forum and not post political material, no matter how important it might be to you or anyone else, even if it is just informational only. Mr. Duffy did not create and maintain the for any individual to use it as a vehicle for their own political views unrelated to implanted defibrillators and how those of us who have them are coping. I also noted right away that you chose not to sign your posting or otherwise identify yourself beyond the anonymity of your e-mail address. Thank you. Bill

Mahan Sneak preview the all-new .com. It's not radically different. Just radically better.

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